Imperial College London
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ProfessorAlisonMcGregor

Faculty of Medicine, Department of Surgery & Cancer

Professor of Musculoskeletal Biodynamics
 
 
 
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Contact

 

+44 (0)20 7594 2972a.mcgregor

 
 
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Location

 

Room 202ASir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Duffell:2017:10.1016/j.gaitpost.2017.06.015,
author = {Duffell, LD and Jordan, SJ and Cobb, JP and McGregor, AH},
doi = {10.1016/j.gaitpost.2017.06.015},
journal = {Gait and Posture},
pages = {246--251},
title = {Gait adaptations with aging in healthy participants and people with knee joint osteoarthritis},
url = {http://dx.doi.org/10.1016/j.gaitpost.2017.06.015},
volume = {57},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The relationship between age and gait characteristics in people with and without medial compartment osteoarthritis (OA) remains unclear. We aimed to characterize this relationship and to relate biomechanical and structural parameters in a subset of OA patients. Twenty five participants with diagnosed unilateral medial knee OA and 84 healthy participants, with no known knee pathology were recruited. 3D motion capture was used to analyse sagittal and coronal plane gait parameters while participants walked at a comfortable speed. Participants were categorized according to age (18–30, 31–59 and 60+ years), and those with and without OA were compared between and within age groups. In a subset of OA patients, clinically available Computed Tomography images were used to assess joint structure. Differences in coronal plane kinematics at the hip and knee were noted in participants with OA particularly those who were older compared with our healthy controls, as well as increased knee moments. Knee adduction moment correlated with structural parameters in the subset of OA patients. Increased knee moments and altered kinematics were observed in older participants presenting with OA only, which seem to be related to morphological changes in the joint due to OA, as opposed to being related to the initial cause of medial knee OA.
AU  - Duffell,LD
AU  - Jordan,SJ
AU  - Cobb,JP
AU  - McGregor,AH
DO  - 10.1016/j.gaitpost.2017.06.015
EP  - 251
PY  - 2017///
SN  - 0966-6362
SP  - 246
TI  - Gait adaptations with aging in healthy participants and people with knee joint osteoarthritis
T2  - Gait and Posture
UR  - http://dx.doi.org/10.1016/j.gaitpost.2017.06.015
UR  - http://hdl.handle.net/10044/1/52815
VL  - 57
ER  -
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