Imperial College London

Dr. Anna C. Need

Faculty of MedicineDepartment of Brain Sciences

Honorary Lecturer
 
 
 
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Contact

 

+44 (0)20 3313 8436a.need Website

 
 
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Location

 

7N2aCommonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Need:2022,
author = {Need, AC and Goldstein, DB},
journal = {Dialogues in Clinical Neuroscience},
title = {Neuropsychiatric Genomics in Precision Medicine: Diagnostics, Gene discovery, and Translation},
year = {2022}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Only a few years after its development, next generation sequencing is rapidly becoming an essential part of clinical care for patients with serious neurological conditions, especially in the diagnosis of early onset and severe presentations. Beyond this diagnostic role, there has been an explosion in definitive gene discovery in a range of neuropsychiatric diseases. This is providing new pointers to underlying disease biology, and beginning to outline a new framework for genetic stratification of neuropsychiatric disease, with clear relevance to both individual treatment optimization and clinical trial design. Here we outline these developments and chart the expected impact on the treatment of neurological, neurodevelopmental and psychiatric disease.
AU - Need,AC
AU - Goldstein,DB
PY - 2022///
SN - 1958-5969
TI - Neuropsychiatric Genomics in Precision Medicine: Diagnostics, Gene discovery, and Translation
T2 - Dialogues in Clinical Neuroscience
ER -