Imperial College London
Alternate

Professor Toby Prevost

Faculty of Medicine, School of Public Health

Visiting Professor
 
 
 
//

Contact

 

a.prevost

 
 
//

Location

 

57Stadium HouseWhite City Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Farquhar:2016:10.1186/s13063-016-1304-6,
author = {Farquhar, MC and Prevost, AT and McCrone, P and Brafman-Price, B and Bentley, A and Higginson, IJ and Todd, CJ and Booth, S},
doi = {10.1186/s13063-016-1304-6},
journal = {Trials},
title = {The clinical and cost effectiveness of a Breathlessness Intervention Service for patients with advanced non-malignant disease and their informal carers: mixed findings of a mixed method randomised controlled trial},
url = {http://dx.doi.org/10.1186/s13063-016-1304-6},
volume = {17},
year = {2016}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundBreathlessness is the most common and intrusive symptom of advanced non-malignant respiratory and cardiac conditions. The Breathlessness Intervention Service (BIS) is a multi-disciplinary complex intervention, theoretically underpinned by a palliative care approach, utilising evidence-based non-pharmacological and pharmacological interventions to support patients with advanced disease in managing their breathlessness. Having published the effectiveness and cost effectiveness of BIS for patients with advanced cancer and their carers, we sought to establish its effectiveness, and cost effectiveness, in advanced non-malignant conditions.MethodsThis was a single-centre Phase III fast-track single-blind mixed method RCT of BIS versus standard care for breathless patients with non-malignant conditions and their carers. Randomisation was to one of two groups (randomly permuted blocks). Eighty-seven patients referred to BIS were randomised (intervention arm n = 44; control arm n = 43 received BIS after four-week wait); 79 (91 %) completed to key outcome measurement. The primary outcome measure was 0–10 numeric rating scale for patient distress due to breathlessness at four weeks. Secondary outcome measures were Chronic Respiratory Questionnaire, Hospital Anxiety and Depression Scale, Client Service Receipt Inventory, EQ-5D and topic-guided interviews.ResultsQualitative analyses showed the positive impact of BIS on patients with non-malignant conditions and their carers; quantitative analyses showed a non-significant greater reduction in the primary outcome (‘distress due to breathlessness’), when compared to standard care, of –0.24 (95 % CI: –1.30, 0.82). BIS resulted in extra mean costs of £799, reducing to £100 when outliers were excluded; neither difference was statistically significant. The quantitative findings contrasted with those previously reported for patients with cancer and their car
AU  - Farquhar,MC
AU  - Prevost,AT
AU  - McCrone,P
AU  - Brafman-Price,B
AU  - Bentley,A
AU  - Higginson,IJ
AU  - Todd,CJ
AU  - Booth,S
DO  - 10.1186/s13063-016-1304-6
PY  - 2016///
SN  - 1745-6215
TI  - The clinical and cost effectiveness of a Breathlessness Intervention Service for patients with advanced non-malignant disease and their informal carers: mixed findings of a mixed method randomised controlled trial
T2  - Trials
UR  - http://dx.doi.org/10.1186/s13063-016-1304-6
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000373488700002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/43901
VL  - 17
ER  -
Download