Imperial College London
Alternate

Professor Toby Prevost

Faculty of Medicine, School of Public Health

Visiting Professor
 
 
 
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Contact

 

a.prevost

 
 
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Location

 

57Stadium HouseWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Booth:2015:10.1038/jhh.2015.23,
author = {Booth, HP and Prevost, AT and Gulliford, MC},
doi = {10.1038/jhh.2015.23},
journal = {Journal of Human Hypertension},
pages = {40--45},
title = {Severity of obesity and management of hypertension, hypercholesterolaemia and smoking in primary care: population-based cohort study},
url = {http://dx.doi.org/10.1038/jhh.2015.23},
volume = {30},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Obesity and obesity-associated cardiovascular risk are increasing worldwide. This study aimed to determine how different levels of obesity are associated with the management of smoking, hypertension and hypercholesterolaemia in primary care. We conducted a cohort study of adults aged 30–100 years in England, sampled from the primary care electronic health records in the Clinical Practice Research Datalink. Prevalence, treatment and control were estimated for each risk factor by body mass index (BMI) category. Adjusted odds ratios (AOR) were estimated, allowing for age, gender, comorbidity and socioeconomic status, with normal weight as reference category. Data were analysed for 247 653 patients including 153 308 (62%) with BMI recorded, of whom 46 149 (30%) were obese. Participants were classified into simple (29 257), severe (11 059) and morbid obesity (5833) categories. Smoking declined with the increasing BMI category, but smoking cessation treatment increased. Age-standardised hypertension prevalence was twice as high in morbid obesity (men 78.6%; women 66.0%) compared with normal weight (men 37.3%; women 29.4%). Hypertension treatment was more frequent (AOR 1.75, 1.59–1.92) but hypertension control less frequent (AOR 0.63, 0.59–0.69) in morbid obesity, with similar findings for severe obesity. Hypercholesterolaemia was more frequent in morbid obesity (men 48.2%; women 36.3%) than normal weight (men 25.0%; women 20.0%). Lipid lowering therapy was more frequent in morbid obesity (AOR 1.83, 1.61–2.07) as was cholesterol control (AOR 1.19, 1.06–1.34). Increasing obesity category is associated with elevated risks from hypertension and hypercholesterolaemia. Inadequate hypertension control in obesity emerges as an important target for future interventions.
AU  - Booth,HP
AU  - Prevost,AT
AU  - Gulliford,MC
DO  - 10.1038/jhh.2015.23
EP  - 45
PY  - 2015///
SN  - 0950-9240
SP  - 40
TI  - Severity of obesity and management of hypertension, hypercholesterolaemia and smoking in primary care: population-based cohort study
T2  - Journal of Human Hypertension
UR  - http://dx.doi.org/10.1038/jhh.2015.23
UR  - http://hdl.handle.net/10044/1/56615
VL  - 30
ER  -
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