Imperial College London
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Dr Andrew D. Scott

Faculty of Medicine, National Heart & Lung Institute

Honorary Senior Research Fellow
 
 
 
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Contact

 

+44 (0)20 7352 8121 ext 2937a.scott07

 
 
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Location

 

Cardiovascular MR UnitRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Huo:2024:10.1002/mrm.30012,
author = {Huo, Z and Wen, K and Luo, Y and Neji, R and Kunze, KP and Ferreira, PF and Pennell, DJ and Scott, AD and Nielles-Vallespin, S},
doi = {10.1002/mrm.30012},
journal = {Magnetic Resonance in Medicine},
pages = {2403--2416},
title = {Referenceless Nyquist ghost correction outperforms standard navigator-based method and improves efficiency of in vivo diffusion tensor cardiovascular magnetic resonance},
url = {http://dx.doi.org/10.1002/mrm.30012},
volume = {91},
year = {2024}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - PURPOSE: The study aims to assess the potential of referenceless methods of EPI ghost correction to accelerate the acquisition of in vivo diffusion tensor cardiovascular magnetic resonance (DT-CMR) data using both computational simulations and data from in vivo experiments. METHODS: Three referenceless EPI ghost correction methods were evaluated on mid-ventricular short axis DT-CMR spin echo and STEAM datasets from 20 healthy subjects at 3T. The reduced field of view excitation technique was used to automatically quantify the Nyquist ghosts, and DT-CMR images were fit to a linear ghost model for correction. RESULTS: Numerical simulation showed the singular value decomposition (SVD) method is the least sensitive to noise, followed by Ghost/Object method and entropy-based method. In vivo experiments showed significant ghost reduction for all correction methods, with referenceless methods outperforming navigator methods for both spin echo and STEAM sequences at b = 32, 150, 450, and 600     smm - 2   $$ {\mathrm{smm}}^{-2} $$  . It is worth noting that as the strength of the diffusion encoding increases, the performance gap between the referenceless method and the navigator-based method diminishes. CONCLUSION: Referenceless ghost correction effectively reduces Nyquist ghost in DT-CMR data, showing promise for enhancing the accuracy and efficiency of measurements in clinical practice without the need for any additional reference scans.
AU  - Huo,Z
AU  - Wen,K
AU  - Luo,Y
AU  - Neji,R
AU  - Kunze,KP
AU  - Ferreira,PF
AU  - Pennell,DJ
AU  - Scott,AD
AU  - Nielles-Vallespin,S
DO  - 10.1002/mrm.30012
EP  - 2416
PY  - 2024///
SN  - 0740-3194
SP  - 2403
TI  - Referenceless Nyquist ghost correction outperforms standard navigator-based method and improves efficiency of in vivo diffusion tensor cardiovascular magnetic resonance
T2  - Magnetic Resonance in Medicine
UR  - http://dx.doi.org/10.1002/mrm.30012
UR  - https://www.ncbi.nlm.nih.gov/pubmed/38263908
UR  - https://onlinelibrary.wiley.com/doi/10.1002/mrm.30012
UR  - http://hdl.handle.net/10044/1/109177
VL  - 91
ER  -
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