Imperial College London

ProfessorAlisonHolmes

Faculty of MedicineDepartment of Infectious Disease

Professor of Infectious Diseases
 
 
 
//

Contact

 

+44 (0)20 3313 1283alison.holmes

 
 
//

Location

 

8N16Hammersmith HospitalHammersmith Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Borek:2021:10.1186/s43058-021-00209-7,
author = {Borek, AJ and Campbell, A and Dent, E and Moore, M and Butler, CC and Holmes, A and Walker, AS and McLeod, M and Tonkin-Crine, S and STEP-UP, study team},
doi = {10.1186/s43058-021-00209-7},
journal = {Implementation Science Communications},
title = {Development of an intervention to support the implementation of evidence-based strategies for optimising antibiotic prescribing in general practice.},
url = {http://dx.doi.org/10.1186/s43058-021-00209-7},
volume = {2},
year = {2021}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BACKGROUND: Trials show that antimicrobial stewardship (AMS) strategies, including communication skills training, point-of-care C-reactive protein testing (POC-CRPT) and delayed prescriptions, help optimise antibiotic prescribing and use in primary care. However, the use of these strategies in general practice is limited and inconsistent. We aimed to develop an intervention to enhance uptake and implementation of these strategies in primary care. METHODS: We drew on the Person-Based Approach to develop an implementation intervention in two stages. (1) Planning and design: We defined the problem in behavioural terms drawing on existing literature and conducting primary qualitative research (nine focus groups) in high-prescribing general practices. We identified 'guiding principles' with intervention objectives and key features and developed logic models representing intended mechanisms of action. (2) Developing the intervention: We created prototype intervention materials and discussed and refined these with input from 13 health professionals and 14 citizens in two sets of design workshops. We further refined the intervention materials following think-aloud interviews with 22 health professionals. RESULTS: Focus groups highlighted uncertainties about how strategies could be used. Health professionals in the workshops suggested having practice champions, brief summaries of each AMS strategy and evidence supporting the AMS strategies, and they and citizens gave examples of helpful communication strategies/phrases. Think-aloud interviews helped clarify and shorten the text and user journey of the intervention materials. The intervention comprised components to support practice-level implementation: antibiotic champions, practice meetings with slides provided, and an 'implementation support' website section, and components to support individual-level uptake: website sections on each AMS strategy (with evidence, instructions, links to electronic resources) and materi
AU - Borek,AJ
AU - Campbell,A
AU - Dent,E
AU - Moore,M
AU - Butler,CC
AU - Holmes,A
AU - Walker,AS
AU - McLeod,M
AU - Tonkin-Crine,S
AU - STEP-UP,study team
DO - 10.1186/s43058-021-00209-7
PY - 2021///
SN - 2662-2211
TI - Development of an intervention to support the implementation of evidence-based strategies for optimising antibiotic prescribing in general practice.
T2 - Implementation Science Communications
UR - http://dx.doi.org/10.1186/s43058-021-00209-7
UR - https://www.ncbi.nlm.nih.gov/pubmed/34526140
UR - http://hdl.handle.net/10044/1/100871
VL - 2
ER -