Professor Anne Lingford-Hughes is Head, Centre for Psychiatry and Professor of Addiction Biology at Imperial College London. She is also a Consultant Psychiatrist with a particular interest in pharmacological treatments of alcohol problems and other substance addictions at Central North West London NHS Foundation Trust. Her research has focused on using neuroimaging and neuropharmacological challenges to characterize the neurobiology of addiction. In particular she has used positron emission tomography (PET) and MR to characterize the dopamine (DRD2, DRD3), opioid (mu), GABA-benzodiazepine (a5 subtype), GABA-B, NK1 receptor systems in a range of substance addictions including alcoholism, cocaine and opiate dependence as well disordered gambling. More recently she has been exploring neuroinflammatory processes and amyloid deposition in alcoholism. The aim of her research programme is to better understand neurobiology underpinning these disorders to improve treatment.
If you are interested in finding out more about our studies into alcoholism and participating if you are abstinent and well, please email email@example.com for more information.
Professor Anne Lingford-Hughes leads the MRC Addiction Research Clinical Training Programme (MARC) with Prof Colin Drummond, IOPPN, KCL and Prof Matt Hickman, University of Bristol. For events and opportunities associated with MARC see https://www.imperial.ac.uk/medicine/study/mrc-addiction-research-clinical-training/. Please contact us if you are a clinician interested in exploring the possibility of conducting a PhD in the area of addiction to develop your career in this vital clinical area.
Prof Lingford-Hughes is past Hon. General Secretary of the British Association for Psychopharmacology. She co-developed and wrote their guidelines about the pharmacological management of substance misuse and addiction and comorbidity with psychiatric disorders. She has also contributed to NICE guidance regarding pharmacotherapy of opiate detoxification and alcohol misuse and dependence.
She is currently Chair of the Academic Faculty of RCPsych.
She graduated in medicine from Oxford University, completed her PhD at Cambridge University, and trained in psychiatry at The Bethlem and Maudsley Hospitals and Institute of Psychiatry.
et al., 2017, Decreased hippocampal translocator protein (18kDa) expression in alcohol dependence: a [C-11] PBR28 PET study, Translational Psychiatry, Vol:7, ISSN:2158-3188
et al., 2017, Neural substrates of cue reactivity and craving in gambling disorder, Translational Psychiatry, Vol:7, ISSN:2158-3188
Lingford-Hughes A, 2017, Introduction to Horizons Review series on neuroimaging, Addiction, Vol:112, ISSN:0965-2140, Pages:205-206
et al., 2017, The ICCAM platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part B: fMRI description, Journal of Psychopharmacology, Vol:31, ISSN:0269-8811, Pages:3-16
et al., 2017, Naltrexone ameliorates functional network abnormalities in alcohol-dependent individuals., Addict Biol