Summary
I use a novel combination of experimental, mathematical and bioinformatic techniques to investigate cell-mediated immunity. My aim is to develop a predictive mathematical model of the human in vivo CD8+ T cell response in order to prevent and alleviate viral infection.
Members of the GrouP
Current
David Vickers
Recent
Nafisa-Katrin Seich al Basatena
Ulrich Kadolsky (u.kadolsky01@imperial.ac.uk)
Aidan Macnamara (aidan.macnamara@gmail.com)
Sukhdeep Singh (sukhdeepsingh.bio@googlemail.com)
Background
My initial training was in theoretical physics. I have a BSc in Physics (1st class hons. University College London), an MSc in Mathematics (distinction, Imperial College London) and a PhD in Theoretical Particle Physics (title: "Non Commutative Geometry", University of Durham). I then worked as a mathematical modeller for the UK government for 2 years before crossing disciplines to Mathematical Immunology. I held a Wellcome Trust Fellowship at Imperial College London and then a Leverhulme Trust Fellowship at the University of Oxford before returning to Imperial as a lecturer.
For research interests and selected publications please see my group webpage.
oPPORTUNITIES
Funded PhD positions available:
Please contact me if you wish to discuss these opportunities further.
software
Selected Publications
Journal Articles
Zhang Y, Yan AWC, Boelen L, et al. , 2023, KIR-HLA interactions extend human CD8+T cell lifespan in vivo, Journal of Clinical Investigation, Vol:133, ISSN:0021-9738