Imperial College London
Alternate

ProfessorBryonyFranklin

Faculty of Medicine, Department of Surgery & Cancer

Visiting Professor
 
 
 
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Contact

 

b.deanfranklin

 
 
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Location

 

Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Charani:2021:10.1016/j.lanepe.2021.100161,
author = {Charani, E and McKee, M and Ahmad, R and Balasegaram, M and Bonaconsa, C and Merrett, GB and Busse, R and Carter, V and Castro-Sanchez, E and Franklin, BD and Georgiou, P and Hill-Cawthorne, K and Hope, W and Imanaka, Y and Kambugu, A and Leather, AJM and Mbamalu, O and McLeod, M and Mendelson, M and Mpundu, M and Rawson, TM and Ricciardi, W and Rodriguez-Manzano, J and Singh, S and Tsioutis, C and Uchea, C and Zhu, N and Holmes, AH},
doi = {10.1016/j.lanepe.2021.100161},
journal = {The Lancet Regional Health - Europe},
pages = {1--10},
title = {Optimising antimicrobial use in humans-review of current evidence and an interdisciplinary consensus on key priorities for research},
url = {http://dx.doi.org/10.1016/j.lanepe.2021.100161},
volume = {7},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Addressing the silent pandemic of antimicrobial resistance (AMR) is a focus of the 2021 G7 meeting. A major driver of AMR and poor clinical outcomes is suboptimal antimicrobial use. Current research in AMR is inequitably focused on new drug development. To achieve antimicrobial security we need to balance AMR research efforts between development of new agents and strategies to preserve the efficacy and maximise effectiveness of existing agents.Combining a review of current evidence and multistage engagement with diverse international stakeholders (including those in healthcare, public health, research, patient advocacy and policy) we identified research priorities for optimising antimicrobial use in humans across four broad themes: policy and strategic planning; medicines management and prescribing systems; technology to optimise prescribing; and context, culture and behaviours. Sustainable progress depends on: developing economic and contextually appropriate interventions; facilitating better use of data and prescribing systems across healthcare settings; supporting appropriate and scalable technological innovation. Implementing this strategy for AMR research on the optimisation of antimicrobial use in humans could contribute to equitable global health security.
AU  - Charani,E
AU  - McKee,M
AU  - Ahmad,R
AU  - Balasegaram,M
AU  - Bonaconsa,C
AU  - Merrett,GB
AU  - Busse,R
AU  - Carter,V
AU  - Castro-Sanchez,E
AU  - Franklin,BD
AU  - Georgiou,P
AU  - Hill-Cawthorne,K
AU  - Hope,W
AU  - Imanaka,Y
AU  - Kambugu,A
AU  - Leather,AJM
AU  - Mbamalu,O
AU  - McLeod,M
AU  - Mendelson,M
AU  - Mpundu,M
AU  - Rawson,TM
AU  - Ricciardi,W
AU  - Rodriguez-Manzano,J
AU  - Singh,S
AU  - Tsioutis,C
AU  - Uchea,C
AU  - Zhu,N
AU  - Holmes,AH
DO  - 10.1016/j.lanepe.2021.100161
EP  - 10
PY  - 2021///
SN  - 2666-7762
SP  - 1
TI  - Optimising antimicrobial use in humans-review of current evidence and an interdisciplinary consensus on key priorities for research
T2  - The Lancet Regional Health - Europe
UR  - http://dx.doi.org/10.1016/j.lanepe.2021.100161
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000684625800009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.sciencedirect.com/science/article/pii/S2666776221001381?via%3Dihub
UR  - http://hdl.handle.net/10044/1/93001
VL  - 7
ER  -
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