Research Interests: Nanopore electrodes, biosensors, single molecule detection.
Development of nanopore platforms for single molecule biosensing applications
Nanopore-based sensors systems have proven to be exceptionally powerful in detection and characterization of nucleic acids, proteins and nucleic acid-protein complexes. The most widely employed configuration of this technique comprises a nanometer-sized pore opened between two reservoirs containing an electrolyte. The translocation of molecules across the nanopore under the influence of an applied potential results in a measurable electrical signal whose magnitude and duration can reveal information about the nature and properties of the molecule traversing the nanopore. Our research aims to design and develop nanopore platforms for single molecule biosensing applications.