Imperial College London
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Professor Christl Donnelly CBE FMedSci FRS

Faculty of Medicine, School of Public Health

Visiting Professor
 
 
 
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Contact

 

c.donnelly Website

 
 
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Location

 

School of Public HealthWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Van:2015:10.1038/sdata.2015.19,
author = {Van, Kerkhove MD and Bento, AI and Mills, HL and Ferguson, NM and Donnelly, CA},
doi = {10.1038/sdata.2015.19},
journal = {Scientific Data},
pages = {150019--150019},
title = {A review of epidemiological parameters from Ebola outbreaks to inform early public health decision-making.},
url = {http://dx.doi.org/10.1038/sdata.2015.19},
volume = {2},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The unprecedented scale of the Ebola outbreak in West Africa has, as of 29 April 2015, resulted in more than 10,884 deaths among 26,277 cases. Prior to the ongoing outbreak, Ebola virus disease (EVD) caused relatively small outbreaks (maximum outbreak size 425 in Gulu, Uganda) in isolated populations in central Africa. Here, we have compiled a comprehensive database of estimates of epidemiological parameters based on data from past outbreaks, including the incubation period distribution, case fatality rate, basic reproduction number (R 0 ), effective reproduction number (R t ) and delay distributions. We have compared these to parameter estimates from the ongoing outbreak in West Africa. The ongoing outbreak, because of its size, provides a unique opportunity to better understand transmission patterns of EVD. We have not performed a meta-analysis of the data, but rather summarize the estimates by virus from comprehensive investigations of EVD and Marburg outbreaks over the past 40 years. These estimates can be used to parameterize transmission models to improve understanding of initial spread of EVD outbreaks and to inform surveillance and control guidelines.
AU  - Van,Kerkhove MD
AU  - Bento,AI
AU  - Mills,HL
AU  - Ferguson,NM
AU  - Donnelly,CA
DO  - 10.1038/sdata.2015.19
EP  - 150019
PY  - 2015///
SN  - 2052-4463
SP  - 150019
TI  - A review of epidemiological parameters from Ebola outbreaks to inform early public health decision-making.
T2  - Scientific Data
UR  - http://dx.doi.org/10.1038/sdata.2015.19
UR  - http://hdl.handle.net/10044/1/23575
VL  - 2
ER  -
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