Imperial College London
Alternate

ProfessorCristinaLo Celso

Faculty of Natural Sciences, Department of Life Sciences

Co-Director Centre for Haematology & Prof Stem Cell Biology
 
 
 
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Contact

 

c.lo-celso

 
 
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Location

 

548Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

90 results found

Strydom N, Lo Celso C, Scott M, Rankin Set al., 2011, Using intravital microscopy to investigate the molecules that regulate the homing of senescent neutrophils to the bone marrow and their phagocytosis by bone marrow macrophages, Annual Congress of the British-Society-for-Immunology, Publisher: WILEY-BLACKWELL, Pages: 127-127, ISSN: 0019-2805

Conference paper

Silberstein L, Osawa M, Lin C, Kharchenko P, Lo Celso C, Aribeana C, Scadden DTet al., 2011, Real-Time RT-PCR Analysis of Individual Osteolineage Cells within the Hematopoietic Stem Cell Niche, 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, Publisher: AMER SOC HEMATOLOGY, Pages: 1028-1029, ISSN: 0006-4971

Conference paper

Lo Celso C, Scadden DT, 2011, The haematopoietic stem cell niche at a glance, JOURNAL OF CELL SCIENCE, Vol: 124, Pages: 3529-3535, ISSN: 0021-9533

Journal article

Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DAet al., 2011, Differential niche and Wnt requirements during acute myeloid leukemia progression, BLOOD, Vol: 118, Pages: 2849-2856, ISSN: 0006-4971

Journal article

Cornejo MG, Mabialah V, Sykes SM, Khandan T, Lo Celso C, Lopez CK, Rivera-Munoz P, Rameau P, Tothova Z, Aster JC, DePinho RA, Scadden DT, Gilliland DG, Mercher Tet al., 2011, Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification, BLOOD, Vol: 118, Pages: 1264-1273, ISSN: 0006-4971

Journal article

Rodriguez S, Wang L, Mumaw C, Srour EF, Lo Celso C, Nakayama K-I, Carlesso Net al., 2011, The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs, BLOOD, Vol: 117, Pages: 6509-6519, ISSN: 0006-4971

Journal article

Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Lo Celso C, Tsuyuzaki H, Sato T, Cote D, Sykes M, Strom TB, Scadden DT, Lin CPet al., 2011, <i>In vivo</i> imaging of T<sub>reg</sub> cells providing immune privilege to the haematopoietic stem-cell niche, NATURE, Vol: 474, Pages: 216-U256, ISSN: 0028-0836

Journal article

Sanchez-Aguilera A, Lee Y-J, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Dorrance A, Luo HR, Scadden DT, Williams DAet al., 2011, Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 108, Pages: 9607-9612, ISSN: 0027-8424

Journal article

Lo Celso C, Lin CP, Scadden DT, 2011, <i>In vivo</i> imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow, NATURE PROTOCOLS, Vol: 6, Pages: 1-14, ISSN: 1754-2189

Journal article

Sanchez-Aguilera A, Lee Y-J, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Adrienne D, Luo HR, Scadden DT, Williams DAet al., 2010, Vav1 Regulates Perivascular Homing, Bone Marrow Retention and Engraftment of Hematopoietic Stem Cells Via SDF1a Signaling, 52nd Annual Meeting of the American-Society-of-Hematology (ASH), Publisher: AMER SOC HEMATOLOGY, Pages: 179-179, ISSN: 0006-4971

Conference paper

Lane SW, Sykes SM, Ferraro F, Lin CP, Gilliland DG, Williams DA, Scadden DT, Lo Celso Cet al., 2010, LEUKEMIA STEM CELLS OCCUPY NICHES THAT ARE PHYSICALLY DISTINCT AND INDEPENDENT OF THE NORMAL CONSTRAINTS THAT APPLY TO HEMATOPOIETIC STEM CELLS, 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells, Publisher: ELSEVIER SCIENCE INC, Pages: S38-S38, ISSN: 0301-472X

Conference paper

Lane SW, Sykes SM, Al-Shahrour F, Shterental S, Paktinat M, Lo Celso C, Jesneck JL, Ebert BL, Williams DA, Gilliland DGet al., 2010, The <i>Apc<SUP>min</SUP></i> mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS, BLOOD, Vol: 115, Pages: 3489-3497, ISSN: 0006-4971

Journal article

Lo Celso C, 2010, Every cloud has a silver lining, BLOOD, Vol: 115, Pages: 438-439, ISSN: 0006-4971

Journal article

Ferraro F, Lo Celso C, Scadden D, 2010, ADULT STEM CELLS AND THEIR NICHES, CELL BIOLOGY OF STEM CELLS, Vol: 695, Pages: 155-168, ISSN: 0065-2598

Journal article

Lo Celso C, Wu JW, Lin CP, 2009, <i>In vivo</i> imaging of hematopoietic stem cells and their microenvironment, JOURNAL OF BIOPHOTONICS, Vol: 2, Pages: 619-631, ISSN: 1864-063X

Journal article

Adams GB, Alley IR, Chung U-I, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DTet al., 2009, Haematopoietic stem cells depend on Gα<sub>s</sub>-mediated signalling to engraft bone marrow, NATURE, Vol: 459, Pages: 103-U111, ISSN: 0028-0836

Journal article

Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Cote D, Rowe DW, Lin CP, Scadden DTet al., 2009, Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche, NATURE, Vol: 457, Pages: 92-U96, ISSN: 0028-0836

Journal article

Szotek PP, Chang HL, Brennand K, Fujino A, Pieretti-Vanmarcke R, Lo Celso C, Dombkowski D, Preffer F, Cohen KS, Teixeira J, Donahoe PKet al., 2008, Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 105, Pages: 12469-12473, ISSN: 0027-8424

Journal article

Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, Lo Celso C, Reynolds G, Milne CD, Paige CJ, Karlsson S, Woo M, Scadden DTet al., 2008, Hematopoietic stem cell responsiveness to exogenous signals is limited by Caspase-3, CELL STEM CELL, Vol: 2, Pages: 584-594, ISSN: 1934-5909

Journal article

Lo Celso C, Berta MA, Braun KM, Frye M, Lyle S, Zouboulis CC, Watt FMet al., 2008, Characterization of bipotential epidermal progenitors derived from human sebaceous gland:: Contrasting roles of c-Myc and β-catenin, STEM CELLS, Vol: 26, Pages: 1241-1252, ISSN: 1066-5099

Journal article

Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, Scadden DTet al., 2008, Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo, CELL STEM CELL, Vol: 2, Pages: 274-283, ISSN: 1934-5909

Journal article

Lo Celso C, Klein RJ, Scadden DT, 2007, Analysis of the hematopoietic stem cell niche., Curr Protoc Stem Cell Biol, Vol: Chapter 2, Pages: Unit-2A.5

Hematopoietic stem cells (HSCs) continuously replenish all blood cell lineages not only to maintain the normal rapid turnover of differentiated cells but also to respond to injury and stress. Cell-extrinsic mechanisms are critical determinants of the fine balance between HSC self-renewal and differentiation. The bone marrow microenvironment has emerged as a new area of intense study to identify which of its many components constitute the HSC niche and regulate HSC fate. While HSCs have been isolated, characterized and used in clinical practice for many years thanks to the development of very specific assays and technology (i.e., bone marrow transplants and fluorescence activated cell sorting), study of the HSC niche has evolved by combining experimental designs developed in different fields. In this unit we describe a collection of protocols spanning a wide range of techniques that can help every researcher tackling questions regarding the nature of the HSC niche.

Journal article

Lo Celso C, Scadden DT, 2007, Stem cells remember their grade, CELL STEM CELL, Vol: 1, Pages: 132-134, ISSN: 1934-5909

Journal article

Lo Celso C, Scadden D, 2007, Isolation and transplantation of hematopoietic stem cells (HSCs)., J Vis Exp

Journal article

Estrach S, Ambler CA, Lo Celso C, Hozumi K, Watt FMet al., 2006, Jagged 1 is a β-catenin target gene required for ectopic hair follicle formation in adult epidermis, DEVELOPMENT, Vol: 133, Pages: 4427-4438, ISSN: 0950-1991

Journal article

Watt FM, Lo Celso C, Silva-Vargas V, 2006, Epidermal stem cells: an update, CURRENT OPINION IN GENETICS & DEVELOPMENT, Vol: 16, Pages: 518-524, ISSN: 0959-437X

Journal article

Morita K, Lo Celso C, Spencer-Dene B, Zouboulis CC, Watt FMet al., 2006, HAN11 binds mDia1 and controls GLI1 transcriptional activity, JOURNAL OF DERMATOLOGICAL SCIENCE, Vol: 44, Pages: 11-20, ISSN: 0923-1811

Journal article

Silva-Vargas V, Lo Celso C, Giangreco A, Ofstad T, Prowse DM, Braun KM, Watt FMet al., 2005, β-catenin and hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells, DEVELOPMENTAL CELL, Vol: 9, Pages: 121-131, ISSN: 1534-5807

Journal article

Lo Celso C, Prowse DM, Watt FM, 2004, Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours, DEVELOPMENT, Vol: 131, Pages: 1787-1799, ISSN: 0950-1991

Journal article

Medico E, Gentile A, Lo Celso C, Williams TA, Gambarotta G, Trusolino L, Comoglio PMet al., 2001, Osteopontin is an autocrine mediator of hepatocyte growth factor-induced invasive growth, CANCER RESEARCH, Vol: 61, Pages: 5861-5868, ISSN: 0008-5472

Journal article

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