Imperial College London
Alternate

ProfessorCristinaLo Celso

Faculty of Natural Sciences, Department of Life Sciences

Co-Director Centre for Haematology & Prof Stem Cell Biology
 
 
 
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Contact

 

c.lo-celso

 
 
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Location

 

548Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{Khorshed:2016:10.5772/64089,
author = {Khorshed, RA and Lo, Celso C},
booktitle = {Microscopy and Analysis},
doi = {10.5772/64089},
editor = {Stanciu},
publisher = {InTech},
title = {Automated identification and measurement of Hematopoietic Stem Cells in 3D Intravital Microscopy Data},
url = {http://dx.doi.org/10.5772/64089},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - CHAP
AB  - Image analysis and quantification of Haematopoietic stem cells (HSCs) position within their surrounding microenvironment in the bone marrow is a fast growing area of research, as it holds the key to understanding the dynamics of HSC-niche interactions and their multiple implications in normal tissue development and in response to various stress events. However, this area of research is very challenging due to the complex cellular structure of such images. Therefore, automated image analysis tools are required to simplify the biological interpretation of 3D HSC microenvironment images. In this chapter, we describe how 3D intravital microscopy data can be visualised and analysed using a computational method that allows the automated quantification of HSC position relative to surrounding niche components.
AU  - Khorshed,RA
AU  - Lo,Celso C
DO  - 10.5772/64089
PB  - InTech
PY  - 2016///
SN  - 978-953-51-2578-5
TI  - Automated identification and measurement of Hematopoietic Stem Cells in 3D Intravital Microscopy Data
T1  - Microscopy and Analysis
UR  - http://dx.doi.org/10.5772/64089
UR  - http://hdl.handle.net/10044/1/33180
ER  -
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