Imperial College London

Dr Claire Shovlin

Faculty of MedicineNational Heart & Lung Institute

Professor of Practice (Clinical and Molecular Medicine)
 
 
 
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Contact

 

c.shovlin Website

 
 
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Location

 

534Block L Hammersmith HospitalHammersmith Campus

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Summary

 

Summary


 

Selected Publications

Journal Articles

Alsafi A, Jackson JE, Fatania G, et al., 2019, Patients with in-situ metallic coils and amplatzer vascular plugs used to treat pulmonary arteriovenous malformations since 1984 can safely undergo magnetic resonance imaging, British Journal of Radiology, ISSN:0007-1285

Boother EJ, Brownlow S, Tighe HC, et al., 2017, Cerebral abscess associated with odontogenic bacteremias, hypoxemia, and iron loading in immunocompetent patients with right-to-left shunting through pulmonary arteriovenous malformations., Clinical Infectious Diseases, Vol:65, ISSN:1537-6591, Pages:595-603

Shovlin CL, Gilson C, Busbridge M, et al., 2016, Can Iron Treatments Aggravate Epistaxis in Some Patients With Hereditary Hemorrhagic Telangiectasia?, Laryngoscope, Vol:126, ISSN:0023-852X, Pages:2468-2474

Patel T, Elphick A, Jackson JE, et al., 2016, Injections of Intravenous Contrast for Computerized Tomography Scans Precipitate Migraines in Hereditary Hemorrhagic Telangiectasia Subjects at Risk of Paradoxical Emboli: Implications for Right-to-Left Shunt Risks, Headache, Vol:56, ISSN:0017-8748, Pages:1659-1663

Shovlin CL, Awan I, Cahilog Z, et al., 2016, Reported cardiac phenotypes in hereditary hemorrhagic telangiectasia emphasize burdens from arrhythmias, anemia and its treatments, but suggest reduced rates of myocardial infarction, International Journal of Cardiology, Vol:215, ISSN:0167-5273, Pages:179-185

Shovlin CL, Patel T, Jackson JE, 2016, Embolisation of PAVMs reported to improve nosebleeds by a subgroup of patients with hereditary haemorrhagic telangiectasia., Erj Open Res, Vol:2, ISSN:2312-0541

Mollet IG, Patel D, Govani FS, et al., 2016, Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes, PLOS One, Vol:11, ISSN:1932-6203

Shovlin CL, 2015, Circulatory contributors to the phenotype in hereditary hemorrhagic telangiectasia, Frontiers in Genetics, Vol:06, ISSN:1664-8021

Shovlin CL, 2014, Pulmonary arteriovenous malformations., Am J Respir Crit Care Med, Vol:190, Pages:1217-1228

Santhirapala V, Chamali B, McKernan H, et al., 2014, Orthodeoxia and postural orthostatic tachycardia in patients with pulmonary arteriovenous malformations: a prospective 8-year series, Thorax, Vol:69, ISSN:0040-6376, Pages:1046-1047

Howard LSGE, Santhirapala V, Murphy K, et al., 2014, Cardiopulmonary Exercise Testing Demonstrates Maintenance of Exercise Capacity in Patients With Hypoxemia and Pulmonary Arteriovenous Malformations, Chest, Vol:146, ISSN:0012-3692, Pages:709-718

Elphick A, Shovlin CL, 2014, Relationships Between Epistaxis, Migraines, and Triggers in Hereditary Hemorrhagic Telangiectasia, Laryngoscope, Vol:124, ISSN:0023-852X, Pages:1521-1528

Shovlin CL, 2014, Iron deficiency, ischaemic strokes, and right-to-left shunts: From pulmonary arteriovenous malformations to patent foramen ovale?, Intractable Rare Dis Res, Vol:3, ISSN:2186-3644, Pages:60-64

Finnamore HE, Whelan K, Hickson M, et al., 2014, Top dietary iron sources in the UK, British Journal of General Practice, Vol:64, ISSN:0960-1643, Pages:172-173

Santhirapala V, Williams LC, Tighe HC, et al., 2014, Arterial Oxygen Content Is Precisely Maintained by Graded Erythrocytotic Responses in Settings of High/Normal Serum Iron Levels, and Predicts Exercise Capacity: An Observational Study of Hypoxaemic Patients with Pulmonary Arteriovenous Malformations, PLOS One, Vol:9, ISSN:1932-6203

Shovlin CL, Chamali B, Santhirapala V, et al., 2014, Ischaemic Strokes in Patients with Pulmonary Arteriovenous Malformations and Hereditary Hemorrhagic Telangiectasia: Associations with Iron Deficiency and Platelets, PLOS One, Vol:9, ISSN:1932-6203

Hosman AE, Devlin HL, Silva BM, et al., 2013, Specific cancer rates may differ in patients with hereditary haemorrhagic telangiectasia compared to controls, Orphanet Journal of Rare Diseases, Vol:8, ISSN:1750-1172

Finnamore H, Le Couteur J, Hickson M, et al., 2013, Hemorrhage-Adjusted Iron Requirements, Hematinics and Hepcidin Define Hereditary Hemorrhagic Telangiectasia as a Model of Hemorrhagic Iron Deficiency, PLOS One, Vol:8, ISSN:1932-6203

Silva BM, Hosman AE, Devlin HL, et al., 2013, Lifestyle and Dietary Influences on Nosebleed Severity in Hereditary Hemorrhagic Telangiectasia, Laryngoscope, Vol:123, ISSN:0023-852X, Pages:1092-1099

Govani FS, Giess A, Mollet IG, et al., 2013, Directional next-generation RNA sequencing and examination of premature termination codon mutations in endoglin/hereditary haemorrhagic telangiectasia., Mol Syndromol, Vol:4, ISSN:1661-8769, Pages:184-196

Devlin HL, Hosman AE, Shovlin CL, 2013, Antiplatelet and Anticoagulant Agents in Hereditary Hemorrhagic Telangiectasia, New England Journal of Medicine, Vol:368, ISSN:0028-4793, Pages:876-878

Mason CG, Shovlin CL, 2012, Flight-related complications are infrequent in patients with hereditary haemorrhagic telangiectasia/pulmonary arteriovenous malformations, despite low oxygen saturations and anaemia, Thorax, Vol:67, ISSN:0040-6376, Pages:80-81

Shovlin CL, 2010, Hereditary haemorrhagic telangiectasia Pathophysiology, diagnosis and treatment, Blood Reviews, Vol:24, ISSN:0268-960X, Pages:203-219

Govani FS, Shovlin CL, 2010, Fine mapping of the hereditary haemorrhagic telangiectasia (HHT)3 locus on chromosome 5 excludes VE-Cadherin-2, Sprouty4 and other interval genes., J Angiogenes Res, Vol:2

Shovlin CL, Angus G, Manning RA, et al., 2010, Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension., Plos One, Vol:5

Shovlin CL, 2009, Ischaemic stroke and thrombolysis- time to consider the HHT question, Ebmj

Govani FS, Shovlin CL, 2009, Hereditary haemorrhagic telangiectasia: a clinical and scientific review, European Journal of Human Genetics, Vol:17, ISSN:1476-5438, Pages:860-871

Shovlin CL, Gibbs JSR, Jackson JE, 2009, Management of pulmonary arteriovenous malformations in pulmonary hypertensive patients: a pressure to embolise?, Eur Respir Rev, Vol:18, Pages:4-6

Shovlin C, Bamford K, Wray D, 2008, Post-NICE 2008: antibiotic prophylaxis prior to dental procedures for patients with pulmonary arteriovenous malformations (PAVMs) and hereditary haemorrhagic telangiectasia, British Dental Journal, Vol:205, ISSN:0007-0610, Pages:531-533

Shovlin CL, Tighe HC, Davies RJ, et al., 2008, Embolisation of pulmonary arteriovenous malformations: no consistent effect on pulmonary artery pressure, European Respiratory Journal, Vol:32, ISSN:0903-1936, Pages:162-169

Shovlin CL, Sodhi V, McCarthy A, et al., 2008, Estimates of maternal risks of pregnancy for women with hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome): suggested approach for obstetric services, Bjog-an International Journal of Obstetrics and Gynaecology, Vol:115, ISSN:1471-0528, Pages:1108-1115

Shovlin CL, Jackson JE, Bamford KB, et al., 2007, Primary determinants of ischaemic stroke/brain abscess risks are independent of severity of pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia, Thorax, Vol:63, ISSN:0040-6376, Pages:259-266

Shovlin C, Sulainam N, Govani FS, et al., 2007, Elevated Factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism, Thrombosis and Haemostasis, Vol:98, ISSN:0340-6245, Pages:1031-1039

Cole SG, Begbie ME, Wallace GMF, et al., 2005, A new locus for hereditary haemorrhagic telangiectasia (HHT3) maps to chromosome 5, Journal of Medical Genetics, Vol:42, ISSN:0022-2593, Pages:577-582

Gupta P, Mordin C, Curtis J, et al., 2002, Pulmonary arteriovenous malformations: Effect of embolization on right-to-left shunt, hypoxemia, and exercise tolerance in 66 patients, American Journal of Roentgenology, Vol:179, ISSN:0361-803X, Pages:347-355

Whittle AT, Davis M, Shovlin CL, et al., 2001, Alveolar macrophage activity and the pulmonary complications of haematopoietic stem cell transplantation, Thorax, Vol:56, ISSN:0040-6376, Pages:941-946

Wallace GMF, Shovlin CL, 2000, A hereditary haemorrhagic telangiectasia family with pulmonary involvement is unlinked to the known HHT genes, endoglin and ALK-1, Thorax, Vol:55, ISSN:0040-6376, Pages:685-690

Shovlin CL, 2000, Genetic aspects of cerebrovascular malformations, Interventional Neuroradiology, Vol:6, ISSN:1123-9344, Pages:107-111

Shovlin CL, Guttmacher AE, Buscarini E, et al., 2000, Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome), American Journal of Medical Genetics, Vol:91, ISSN:0148-7299, Pages:66-67

Shovlin CL, 1999, Supermodels and disease: insights from the HHT mice, Journal of Clinical Investigation, Vol:104, ISSN:0021-9738, Pages:1335-1336

Shovlin CL, Letarte M, 1999, Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations: issues in clinical management and review of pathogenic mechanisms, Thorax, Vol:54, ISSN:0040-6376, Pages:714-729

Shovlin CL, 1998, Glaxo/MRS Young Investigator Medal. Molecular studies on adenosine deaminase deficiency and hereditary haemorrhagic telangiectasia., Clinical Science, Vol:94, ISSN:0143-5221, Pages:207-218

Shovlin CL, Hughes JMB, Scott J, et al., 1997, Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia, American Journal of Human Genetics, Vol:61, ISSN:0002-9297, Pages:68-79

Shovlin CL, 1996, Streamlined procedures for screening a P1 library., Biotechniques, Vol:21, ISSN:0736-6205, Pages:388-390

Shovlin CL, Scott J, 1996, Inherited diseases of the vasculature, Annual Review of Physiology, Vol:58, ISSN:0066-4278, Pages:483-507

Shovlin CL, Winstock AR, Peters AM, et al., 1995, Medical complications of pregnancy in hereditary haemorrhagic telangiectasia, QJM-an International Journal of Medicine, Vol:88, ISSN:1460-2725, Pages:879-887

SHOVLIN CL, SIMMONDS HA, FAIRBANKS LD, et al., 1994, ADULT-ONSET IMMUNODEFICIENCY CAUSED BY INHERITED ADENOSINE-DEAMINASE DEFICIENCY, Journal of Immunology, Vol:153, ISSN:0022-1767, Pages:2331-2339

SHOVLIN CL, HUGHES JMB, TUDDENHAM EGD, et al., 1994, A GENE FOR HEREDITARY HEMORRHAGIC TELANGIECTASIA MAPS TO CHROMOSOME 9Q3, Nature Genetics, Vol:6, ISSN:1061-4036, Pages:205-209

Shovlin CL, Hughes JM, Simmonds HA, et al., 1993, Adult presentation of adenosine deaminase deficiency., The Lancet, Vol:341, ISSN:0140-6736

SHOVLIN CL, HUGHES JMB, SIMMONDS HA, et al., 1993, ADULT PRESENTATION OF ADENOSINE-DEAMINASE DEFICIENCY, The Lancet, Vol:341, ISSN:0140-6736, Pages:1471-1471

RAI GS, SHOVLIN C, WESNES KA, 1991, A DOUBLE-BLIND, PLACEBO CONTROLLED-STUDY OF GINKGO-BILOBA EXTRACT (TANAKAN) IN ELDERLY OUTPATIENTS WITH MILD TO MODERATE MEMORY IMPAIRMENT, Current Medical Research and Opinion, Vol:12, ISSN:0300-7995, Pages:350-355

Chapters

Shovlin CL, Ganesan V, 2014, Hereditary hemorrhagic telangiectasia, Up to Date in Clinical Medicine, Editor(s): Ternauer

Shovlin CL, Oh P, 2010, Hereditary hemorrhagic telangiectasia, Molecular Basis of Lung Disease, Editor(s): McCormack, Panos, Trapnell, Springer Science and Business Media, Pages:167-183

Shovlin CL, Jackson JE, 2010, Pulmonary arteriovenous malformations and other pulmonary vascular abnormalities., Murray and Nadel’s Textbook of Respiratory Medicine, Editor(s): Mason, Broaddus, Martin, King, Schraufnagel, Murray, Nadel, Saunders Elsevier, Pages:1261-1282

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