Summary
Charlotte is a Principal Teaching Fellow, specialising in Organic and Medicinal Chemistry. She is involved in the full range of undergraduate teaching activities within the Department, including lecturing and course design. She is also an active member of the pastoral team and projects to improve student experience, such as transition to university.
Charlotte holds additional roles including being a course coordinator for the Chemistry with Medicinal Chemistry degree programme and a Year Tutor for 1st Year Undergraduates and has been the Departmental Disabilities Officer since 2020.
Within education, her interests are particularly related how assessment and feedback can be designed most effectively to support student learning and skills development.
Biographical Details
Before becoming a Teaching Fellow in 2018, Charlotte had been a member of Imperial College since 2016 as a Postdoctoral Research Associate in the group of Professor Ed Tate, working on a Cancer Research UK funded medicinal chemistry project. She has been closely associated with the MRes in Drug Discovery and Development Programme, helping supervise students conducting a wide variety of medicinal chemistry research projects.
Charlotte graduated from the University of Oxford in 2011 with a first-class MChem, completing her final year project with Professor Andrew D. Hamilton on peptide mimetics. Having become fascinated by the challenges and possibilities in applying chemistry to solve biological problems, she moved to the University of Cambridge for her PhD and was a member of the PhD Training Programme in Chemical Biology and Medicinal Chemistry. She completed her PhD under the supervision of Professor Steven V. Ley and Dr James D. Brenton, developing chemical probes of bromodomain to study their therapeutic relevance in ovarian cancer.
Beyond chemistry, Charlotte is a keen musician and singer, and is a currently a member of The Bach Choir.
Selected Publications
Journal Articles
Lim C, Ha KP, Clarke R, et al., 2019, Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus, Bioorganic & Medicinal Chemistry, Vol:27, ISSN:0968-0896, Pages:1-7
Lovell S, Sutherell CL, Tate EW, 2019, Chemical Probes for Proteins and Networks, Mass Spectrometry-based Chemical Proteomics, Pages:127-158
Sutherell CL, Ley SV, 2017, On the Synthesis and Reactivity of 2,3-Dihydropyrrolo[1,2-<i>a</i>]quinazolin-5(1<i>H</i>)-ones, Synthesis-Stuttgart, Vol:49, ISSN:0039-7881, Pages:135-144
Sutherell CL, Tallant C, Monteiro OP, et al., 2016, Identification and Development of 2,3-Dihydropyrrolo[1,2-<i>a</i>]quinazolin-5(1<i>H</i>)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex, Journal of Medicinal Chemistry, Vol:59, ISSN:0022-2623, Pages:5095-5101
Sutherell CL, Thompson S, Scott RTW, et al., 2012, Aryl-linked imidazolidin-2-ones as non-peptidic β-strand mimetics, Chemical Communications, Vol:48, ISSN:1359-7345, Pages:9834-9836