Imperial College London
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Prof Caroline Alexander

Faculty of Medicine, Department of Surgery & Cancer

Professor of Practice (Musculoskeletal Physiotherapy)
 
 
 
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Contact

 

caroline.alexander

 
 
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Location

 

Department of PhysiotherapyCharing Cross HospitalCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{To:2019:10.1016/j.jelekin.2019.07.011,
author = {To, M and Strutton, P and Alexander, C},
doi = {10.1016/j.jelekin.2019.07.011},
journal = {Journal of Electromyography and Kinesiology},
pages = {197--204},
title = {Central fatigue is greater than peripheral fatigue in people with Joint Hypermobility Syndrome},
url = {http://dx.doi.org/10.1016/j.jelekin.2019.07.011},
volume = {48},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Purpose: People with Joint Hypermobility Syndrome (JHS) suffer with fatigue. The purpose of this project was to investigate the contribution of central and peripheral fatigue.Methods: Electrical stimulation of the musculocutaneous nerve to biceps brachii, and transcranial magnetic stimulation over the motor cortex supplying biceps brachii were used. Peripheral and central fatigue were assessed during a control, fatiguing and recovery phase protocol. Results: JHS participants perceived greater fatigue during the protocol compared to a control group and did not recover. Central and peripheral fatigue did not occur in the control group. However, the JHS group showed central fatigue. MEP amplitude increased in the JHS group during the fatiguing protocol (p<0.01) before recovering. Superimposed twitch amplitude increased in the JHS group during the fatiguing protocol and stayed elevated during the recovery phase (p<0.04). Time to peak (TTP) amplitude of the torque generated by the TMS was longer in the JHS group (p<0.05). RMS during MVCs decreased during the fatiguing protocol reaching significance during the recovery phase (p<0.01).Conclusion: JHS participants suffered central but not peripheral fatigue. A modified strength programme to target this is discussed.
AU  - To,M
AU  - Strutton,P
AU  - Alexander,C
DO  - 10.1016/j.jelekin.2019.07.011
EP  - 204
PY  - 2019///
SN  - 1050-6411
SP  - 197
TI  - Central fatigue is greater than peripheral fatigue in people with Joint Hypermobility Syndrome
T2  - Journal of Electromyography and Kinesiology
UR  - http://dx.doi.org/10.1016/j.jelekin.2019.07.011
UR  - http://hdl.handle.net/10044/1/72317
VL  - 48
ER  -
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