Catherine Mansfield is a postdoctoral research associate in the Myocardial Function section of the National Heart and Lung Institute. She currently works as part of the BHF Centre for Regenerative Medicine in the laboratories of Dr Alex Lyon, Dr Cesare Terracciano and Professor Sian Harding. Her current research focusses on assessing the electrophysiological impact of stem cell delivery and engraftment to the failing heart.
Catherine graduated from the University of Sheffield in 2007 with a BSc in Physiology and Pharmacology. She then moved to Imperial College to study for an MRes in Integrative Mammalian Biology where she completed a research project supervised by Professor Sian Harding and Dr Alex Lyon developing an in vivo model of Takotsubo cardiomyopathy - an acute form of heart failure induced by sudden emotional or physical stress.
In 2012 she completed her PhD in the laboratory of Professor Mike Ferenczi at the National Heart and Lung Institute. Her thesis focussed on the mechanics and energetics of cardiac muscle contraction and the mechanism of the Frank-Starling Law of the heart.
She joined the Myocardial Genetics group of Professor Ralph Knöll as a postdoctoral research associate in 2012 where her research focused on investigating the mechanisms of mechanosensation and mechanotransduction in cardiac muscle.
et al., 2021, Ventricular fibrillation mechanism and global fibrillatory organisation are determined by gap junction coupling and fibrosis pattern, Cardiovascular Research, Vol:117, ISSN:0008-6363, Pages:1078-1090
et al., 2020, Prolonged ursodeoxycholic acid administration reduces acute ischaemia-induced arrhythmias in adult rat hearts, Scientific Reports, Vol:10, ISSN:2045-2322, Pages:1-13
et al., 2020, Mediastinal lymphadenopathy, class-switched auto-antibodies and myocardial immune-complexes during heart failure in rodents and humans, Frontiers in Cell and Developmental Biology, Vol:8, ISSN:2296-634X, Pages:1-12
et al., 2020, Short-term angiotensin II treatment regulates cardiac nanomechanics via microtubule modifications., Nanoscale, Vol:12, ISSN:2040-3364, Pages:16315-16329
et al., 2020, Humoral factors in serum of rats with chronic heart failure induce cardiomyocyte hypertrophy and reduce viability., Clinical Medicine (london, England), Vol:20, ISSN:1470-2118, Pages:s107-s107