Imperial College London

ProfessorCharlotteBevan

Faculty of MedicineDepartment of Surgery & Cancer

Professor of Cancer Biology
 
 
 
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Contact

 

charlotte.bevan Website

 
 
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Assistant

 

Mrs Suzy Ford +44 (0)20 7594 2135

 
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Location

 

139ICTEM buildingHammersmith Campus

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Summary

 

Summary

Qualifications and Employment History

  • BA in Natural Sciences (Part II Genetics), University of Cambridge, 1992.
  • Postdoctoral work at London Research Institute, Cancer Research UK, 1996-1999.
  • Joined Imperial College in 1999 as Lecturer and head of the Androgen Signalling Group in the Department of Oncology.
  • Current position: Professor of Cancer Biology, Non-Clinical Head of Prostate Cancer Research in Department of Surgery & Cancer.

Research Interests

  • Mechanisms of androgen receptor action. 
  • Androgen signalling in development and disease.
  • Nuclear receptor coactivators and corepressors.
  • Mechanisms of therapy resistance in hormone-dependent cancers.
  • Novel therapies for prostate cancer.
  • Discovery and validation of biomarkers for prostate cancer.
  • Role of microRNAs in androgen signalling.

 

Teaching Activities

Undergraduate Teaching

  • BSc in Biomedical Science: Lecturer and Course Lead for Cancer Biology year 2
  • Graduate Entry Medical Degree: Theme Lead for MCD (Molecules, Cells & Disease) year 1 
  • BSc in Biochemistry
  • Project supervisor for MBBS BSc projects

Postgraduate Taught Courses

  • MSc Molecular Medicine
  • MRes Cancer Biology
  • MSc Human Reproduction

Postgraduate Supervision

  • PhD project supervisor
  • Masters project supervisor for MRes Cancer Biology, MSc Human Reproduction, MRes Biomedical Sciences, MSc Molecualr Medicine
  • MSc Human Reproduction

 

Other College roles

Member of the 3Rs committee (College)

Member of the Postgraduate Education Committee for Surgery & Cancer

Member of the Academic Opportunities Committee for Surgery & Cancer

Member of the Student Withdrawals/Appeal panel (College)

 

Collaborators and External Committees

Please see "Research" tab above

Selected Publications

Journal Articles

Bevan CL, 2016, WOMEN IN CANCER PROFILE: A gender agenda?, Endocr Relat Cancer, Vol:23, Pages:P5-P8

Fletcher CE, Godfrey JD, Shibakawa A, et al., 2017, A novel role for GSK3 beta as a modulator of Drosha microprocessor activity and MicroRNA biogenesis, Nucleic Acids Research, Vol:45, ISSN:0305-1048, Pages:2809-2828

Leach DA, Powell SM, Bevan CL, 2016, New roles for nuclear receptors in prostate cancer, Endocrine-related Cancer, Vol:23, ISSN:1351-0088, Pages:T85-T108

Metcalf GAD, Shibakawa A, Patel H, et al., 2016, Amplification-Free Detection of Circulating microRNA Biomarkers from Body Fluids Based on Fluorogenic Oligonucleotide-Templated Reaction between Engineered Peptide Nucleic Acid Probes: Application to Prostate Cancer Diagnosis, Analytical Chemistry, Vol:88, ISSN:0003-2700, Pages:8091-8098

Brooke GN, Powell SM, Lavery DN, et al., 2014, Engineered repressors are potent inhibitors of androgen receptor activity, Oncotarget, Vol:5, ISSN:1949-2553, Pages:959-969

Dart DA, Waxman J, Aboagye EO, et al., 2013, Visualising Androgen Receptor Activity in Male and Female Mice, PLOS One, Vol:8, ISSN:1932-6203

Sita-Lumsden A, Dart DA, Waxman J, et al., 2013, Circulating microRNAs as potential new biomarkers for prostate cancer, British Journal of Cancer, Vol:108, ISSN:0007-0920, Pages:1925-1930

Fletcher CE, Dart DA, Sita-Lumsden A, et al., 2012, Androgen-regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer, Human Molecular Genetics, Vol:21, ISSN:0964-6906, Pages:3112-3127

Brooke GN, Culley RL, Dart DA, et al., 2011, FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth, Cancer Research, Vol:71, ISSN:0008-5472, Pages:914-924

Gamble SC, Chotai D, Odontiadis M, et al., 2007, Prohibitin, a protein downregulated by androgens, represses androgen receptor activity, Oncogene, Vol:26, ISSN:0950-9232, Pages:1757-1768

Brooke GN, Parker MG, Bevan CL, 2008, Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression, Oncogene, Vol:27, ISSN:0950-9232, Pages:2941-2950

More Publications