Imperial College London

DrChrisWilson

Faculty of Natural SciencesDepartment of Life Sciences

Honorary Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 2370chris.wilson Website

 
 
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Location

 

N3.11MunroSilwood Park

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Summary

 

Publications

Citation

BibTex format

@unpublished{Nowell:2020:10.1101/2020.09.15.297952,
author = {Nowell, RW and Wilson, CG and Almeida, P and Schiffer, PH and Fontaneto, D and Becks, L and Rodriguez, F and Arkhipova, IR and Barraclough, TG},
doi = {10.1101/2020.09.15.297952},
title = {Evolutionary dynamics of transposable elements in bdelloid rotifers},
url = {http://dx.doi.org/10.1101/2020.09.15.297952},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - UNPB
AB - <jats:title>Abstract</jats:title><jats:p>Transposable elements (TEs) are selfish genomic parasites whose ability to spread autonomously is facilitated by sexual reproduction in their hosts. If hosts become obligately asexual, TE frequencies and dynamics are predicted to change dramatically, but the long-term outcome is unclear. Here, we test current theory using whole-genome sequence data from eight species of bdelloid rotifers, a class of invertebrates where males are thus far unknown. Contrary to expectations, we find a diverse range of active TEs in bdelloid genomes, at an overall frequency within the range seen in sexual species. We find no evidence that TEs are spread by cryptic recombination or restrained by unusual DNA repair mechanisms, but we report that bdelloids share a large and unusual expansion of genes involved in RNAi-mediated TE suppression. This suggests that enhanced cellular defence mechanisms might mitigate the deleterious effects of active TEs and compensate for the consequences of long-term asexuality.</jats:p>
AU - Nowell,RW
AU - Wilson,CG
AU - Almeida,P
AU - Schiffer,PH
AU - Fontaneto,D
AU - Becks,L
AU - Rodriguez,F
AU - Arkhipova,IR
AU - Barraclough,TG
DO - 10.1101/2020.09.15.297952
PY - 2020///
TI - Evolutionary dynamics of transposable elements in bdelloid rotifers
UR - http://dx.doi.org/10.1101/2020.09.15.297952
ER -