Imperial College London

DrClaireMorgan

Faculty of MedicineDepartment of Medicine

Research Associate in Computational Genomics
 
 
 
//

Contact

 

+44 (0)20 7594 2739claire.morgan Website

 
 
//

Location

 

ICTEM buildingHammersmith Campus

//

Summary

 

Summary

My research interests are in combing evolutionary theory and genomics to investigate genetic mechanisms underlying disease.

I earned my B.Sc. in Genetics and Cell Biology at Dublin City University, Ireland. Following a year working as a research technician at the University of Pennsylvania (UPENN), USA, I competed for and was awarded an IRCSET scholarship to pursue my PhD.

My doctoral work investigated the molecular adaptations in genes associated with aging and disease in placental mammals. I used heterogeneous models to identify the earliest diverging placental mammal as the ancestor to Afrotherians (e.g. Elephants and Manatees) and Xenartha (e.g. Armadillos and Sloths).

With a primary degree in genetics and PhD training in evolution, I moved to Imperial college to become expert in Next Generation Sequencing (NGS) analysis. Here as a postdoctoral researcher I combine evolutionary theory and genomics to pinpoint mutations in humans that give rise to disease such as diabetes and heart disease.

Publications

Journals

Moran R, Morgan C, O'Connell M, et al., 2015, A Guide to Phylogenetic Reconstruction Using Heterogeneous Models—A Case Study from the Root of the Placental Mammal Tree, Computation, Vol:3, ISSN:2079-3197, Pages:177-196

Webb AE, Gerek ZN, Morgan CC, et al., 2015, Adaptive Evolution as a Predictor of Species-Specific Innate Immune Response., Mol Biol Evol, Vol:32, ISSN:0737-4038, Pages:1717-1729

Liu S, Lorenzen ED, Fumagalli M, et al., 2014, Population Genomics Reveal Recent Speciation and Rapid Evolutionary Adaptation in Polar Bears, Cell, Vol:157, ISSN:0092-8674, Pages:785-794

Morgan CC, Creevey CJ, O'Connell MJ, et al., 2014, Mitochondrial data are not suitable for resolving placental mammal phylogeny, Mammalian Genome, Vol:25, ISSN:0938-8990, Pages:636-647

Morgan CC, Foster PG, Webb AE, et al., 2013, Heterogeneous models place the root of the placental mammal phylogeny., Mol Biol Evol, Vol:30, ISSN:0737-4038, Pages:2145-2156

More Publications