Imperial College London

DrClaireMorgan

Faculty of MedicineDepartment of Medicine

Research Associate in Computational Genomics
 
 
 
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Contact

 

+44 (0)20 7594 2739claire.morgan Website

 
 
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Location

 

ICTEM buildingHammersmith Campus

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Summary

 

Summary

My research interests are in combing evolutionary theory and genomics to investigate genetic mechanisms underlying disease.

I earned my B.Sc. in Genetics and Cell Biology at Dublin City University, Ireland. Following a year working as a research technician at the University of Pennsylvania (UPENN), USA, I competed for and was awarded an IRCSET scholarship to pursue my PhD.

My doctoral work investigated the molecular adaptations in genes associated with aging and disease in placental mammals. I used heterogeneous models to identify the earliest diverging placental mammal as the ancestor to Afrotherians (e.g. Elephants and Manatees) and Xenartha (e.g. Armadillos and Sloths).

With a primary degree in genetics and PhD training in evolution, I moved to Imperial college to become expert in Next Generation Sequencing (NGS) analysis. Here as a postdoctoral researcher I combine evolutionary theory and genomics to pinpoint mutations in humans that give rise to disease such as diabetes and heart disease.

Publications

Journals

Moran R, Morgan C, O'Connell M, 2015, A Guide to Phylogenetic Reconstruction Using Heterogeneous Models—A Case Study from the Root of the Placental Mammal Tree, Computation, Vol:3, ISSN:2079-3197, Pages:177-196

Webb AE, Gerek ZN, Morgan CC, et al., 2015, Adaptive Evolution as a Predictor of Species-Specific Innate Immune Response., Mol Biol Evol, Vol:32, Pages:1717-1729

Liu S, Lorenzen ED, Fumagalli M, et al., 2014, Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears., Cell, Vol:157, Pages:785-794

Morgan CC, Creevey CJ, O'Connell MJ, 2014, Mitochondrial data are not suitable for resolving placental mammal phylogeny, Mammalian Genome, Vol:25, ISSN:0938-8990, Pages:636-647

Morgan CC, Foster PG, Webb AE, et al., 2013, Heterogeneous models place the root of the placental mammal phylogeny., Mol Biol Evol, Vol:30, Pages:2145-2156

More Publications