Imperial College London
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ProfessorDannyAltmann

Faculty of Medicine, Department of Immunology and Inflammation

Professor of Immunology
 
 
 
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Contact

 

+44 (0)20 3313 8212d.altmann

 
 
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Location

 

5S5CHammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Altmann:2019:10.1111/imm.13062,
author = {Altmann, DM},
doi = {10.1111/imm.13062},
journal = {Immunology},
pages = {1--2},
title = {Knowns and unknowns of tissue-resident memory T cells},
url = {http://dx.doi.org/10.1111/imm.13062},
volume = {157},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Advances in transcriptomics and other approaches are shedding considerable light on tissueresident immune cells as distinct from recirculating cells. The advances encompass antigenpresenting cell subsets, Tregs and importantly, tissueresident memory cells (TRM). What are the transcriptional programmes and functional properties that distinguish the requirements for an effective tissue resident cell in brain relative to lung, skin, adipose tissue or the genital tract? Another important conundrum has been the extent to which TRM cells are specialized either as a ‘sense and alarm’ population or as a local, primed, effector cell population in themselves. These are questions that challenge immunologists to stop thinking in terms of a generic, model, immune response and focus instead on events in the tissue in question.
AU  - Altmann,DM
DO  - 10.1111/imm.13062
EP  - 2
PY  - 2019///
SN  - 0019-2805
SP  - 1
TI  - Knowns and unknowns of tissue-resident memory T cells
T2  - Immunology
UR  - http://dx.doi.org/10.1111/imm.13062
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000465088700001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/69960
VL  - 157
ER  -
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