Publications

BibTex format

@article{Nagel:2024:10.1002/ijc.34864,
author = {Nagel, G and Chen, J and Jaensch, A and Skodda, L and Rodopoulou, S and Strak, M and de, Hoogh K and Andersen, ZJ and Bellander, T and Brandt, J and Fecht, D and Forastiere, F and Gulliver, J and Hertel, O and Hoffmann, B and Hvidtfeldt, UA and Katsouyanni, K and Ketzel, M and Leander, K and Magnusson, PKE and Pershagen, G and Rizzuto, D and Samoli, E and Severi, G and Stafoggia, M and Tjønneland, A and Vermeulen, RCH and Wolf, K and Zitt, E and Brunekreef, B and Hoek, G and Raaschou-Nielsen, O and Weinmayr, G},
doi = {10.1002/ijc.34864},
journal = {International Journal of Cancer},
pages = {1900--1910},
title = {Long-term exposure to air pollution and incidence of gastric and the upper aerodigestive tract cancers in a pooled European cohort: the ELAPSE project},
url = {http://dx.doi.org/10.1002/ijc.34864},
volume = {154},
year = {2024}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Air pollution has been shown to significantly impact human health including cancer. Gastric and upper aerodigestive tract (UADT) cancers are common and increased risk has been associated with smoking and occupational exposures. However, the association with air pollution remains unclear. We pooled European subcohorts (N = 287,576 participants for gastric and N = 297,406 for UADT analyses) and investigated the association between residential exposure to fine particles (PM2.5 ), nitrogen dioxide (NO2 ), black carbon (BC) and ozone in the warm season (O3w ) with gastric and UADT cancer. We applied Cox proportional hazards models adjusting for potential confounders at the individual and area-level. During 5,305,133 and 5,434,843 person-years, 872 gastric and 1139 UADT incident cancer cases were observed, respectively. For gastric cancer, we found no association with PM2.5 , NO2 and BC while for UADT the hazard ratios (95% confidence interval) were 1.15 (95% CI: 1.00-1.33) per 5 μg/m3 increase in PM2.5 , 1.19 (1.08-1.30) per 10 μg/m3 increase in NO2 , 1.14 (1.04-1.26) per 0.5 × 10-5  m-1 increase in BC and 0.81 (0.72-0.92) per 10 μg/m3 increase in O3w . We found no association between long-term ambient air pollution exposure and incidence of gastric cancer, while for long-term exposure to PM2.5 , NO2 and BC increased incidence of UADT cancer was observed.
AU  - Nagel,G
AU  - Chen,J
AU  - Jaensch,A
AU  - Skodda,L
AU  - Rodopoulou,S
AU  - Strak,M
AU  - de,Hoogh K
AU  - Andersen,ZJ
AU  - Bellander,T
AU  - Brandt,J
AU  - Fecht,D
AU  - Forastiere,F
AU  - Gulliver,J
AU  - Hertel,O
AU  - Hoffmann,B
AU  - Hvidtfeldt,UA
AU  - Katsouyanni,K
AU  - Ketzel,M
AU  - Leander,K
AU  - Magnusson,PKE
AU  - Pershagen,G
AU  - Rizzuto,D
AU  - Samoli,E
AU  - Severi,G
AU  - Stafoggia,M
AU  - Tjønneland,A
AU  - Vermeulen,RCH
AU  - Wolf,K
AU  - Zitt,E
AU  - Brunekreef,B
AU  - Hoek,G
AU  - Raaschou-Nielsen,O
AU  - Weinmayr,G
DO  - 10.1002/ijc.34864
EP  - 1910
PY  - 2024///
SN  - 0020-7136
SP  - 1900
TI  - Long-term exposure to air pollution and incidence of gastric and the upper aerodigestive tract cancers in a pooled European cohort: the ELAPSE project
T2  - International Journal of Cancer
UR  - http://dx.doi.org/10.1002/ijc.34864
UR  - https://www.ncbi.nlm.nih.gov/pubmed/38339851
UR  - https://onlinelibrary.wiley.com/doi/10.1002/ijc.34864
UR  - http://hdl.handle.net/10044/1/109415
VL  - 154
ER  -

Download

DrDanielaFecht

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)