Dorian Haskard is Head of the Division of Myocardial and Vascular Biology within NHLI. He was an undergraduate at Oxford University before moving to The Middlesex Hospital Medical School and subsequently into a range of clinical and research posts in London and the US. In 1987 he was awarded a Wellcome Trust Senior Clinical Fellowship at UMDS, Guy's Hospital. Following this he was appointed to Senior Clinical Lectureship at the Royal Postgraduate Medical School, Hammersmith Hospital, being promoted to Reader and then to Professor in 1995.
Professor Haskard has previously held the following leadership positions at Imperial College: British Heart Foundation Sir John McMichael Chair of Cardiovascular Medicine (1995-2016); Head of the Vascular Sciences Section within the National Heart and Lung Institute (2014-2017); and Head of Division of Immunology and Inflammation in the Department of Medicine (2010-2017).
Professor Haskard has given numerous prestigious national and international lectures and is member of a number of learned societies and funding charities. Notably he was Chairman of the Arthritis Research Campaign Fellowship Committee (2000-2005) and Chairman of the British Atherosclerosis Society (2008-2010). He is President of the International Society for Behçet’s Disease (President 2016-2010), and serves on the National Anti-Doping Panel (NADP).
He has directly supervised 7 post-docs; 45 completed PhD students and many MSc, MRes and BSc students have performed projects within his personal research group at Imperial College.
The goal of Professor Haskard's research has been to achieve a greater understanding of the pathophysiology of inflammatory responses affecting the vascular system, with a view eventually to achieving more specific clinical diagnostic tests and therapies. Current work focuses on two main areas in relation to the biology of vascular inflammation and atherosclerosis: (i) mechanisms of macrophage and endothelial cell gene expression, with an emphasis on post-transcriptional RNA regulation, and (ii) the role of antibodies and complement.
Pandey SS, Haskard DO, Khamis RY, 2017, Developing a Strategy for Interventional Molecular Imaging of Oxidized Low-Density Lipoprotein in Atherosclerosis, Molecular Imaging, Vol:16, ISSN:1536-0121
et al., 2017, Zebrafish Model for Functional Screening of Flow-Responsive Genes, Arteriosclerosis Thrombosis and Vascular Biology, Vol:37, ISSN:1079-5642, Pages:130-+
et al., 2017, Hematoma Resolution In Vivo is Mediated by AMP-Activated Kinase (AMPK) and Activating Transcription Factor 1 (ATF1) Via Coregulation of Tissue Homeostatic Genes, 2nd Joint Meeting of the European-Society-for-Microcirculation (ESM) and European-Vascular-Biology-Organisation (EVBO), KARGER, Pages:29-29, ISSN:1018-1172
et al., 2017, AMP-Activated Protein Kinase-Mediated Chromatin Remodelling Redirects Activating Transcription Factor 1 From Cyclic-AMP Response Genes to Heme-Response Genes, 2nd Joint Meeting of the European-Society-for-Microcirculation (ESM) and European-Vascular-Biology-Organisation (EVBO), KARGER, Pages:29-29, ISSN:1018-1172
et al., 2017, Oral Metformin Profoundly Suppresses Atherosclerotic Lesion Development In Vivo Independently of Glucose Lowering in a Mild Hyperlipidemic Model Via AMPK, 2nd Joint Meeting of the European-Society-for-Microcirculation (ESM) and European-Vascular-Biology-Organisation (EVBO), KARGER, Pages:8-9, ISSN:1018-1172