Imperial College London


Faculty of Natural SciencesDepartment of Chemistry




+44 (0)20 7594 5806d.klug




267ChemistrySouth Kensington Campus





David Klug joined the Department of Chemistry in October 1998, having from October 1995 held a joint position in the Departments of Biochemistry and Chemistry.  From October 1990 to September 1995 he was a Royal Society University Research Fellow jointly in Biochemistry and Chemistry.  He graduated in Physics at University College London in 1984, and obtained his Ph.D. at The Royal Institution in 1987.

David is co-founder and Chair of the Institute of Chemical Biology  ( ), which co-ordinates teaching and research activities in Chemical Biology. He also chairs the Single Cell Proteomics Project, a £5 million multidisciplinary collaboration of eight research teams developing and applying novel platform technologies to high throughput and single cell analysis ( and the Proxomics Project, platform technologies for the analysis of oxidative damage to proteins ( More information about David's research group can be found at .






Cilibrizzi A, Terenghi M, Fedorova M, et al., 2017, Small-molecule optical probes for cell imaging of protein sulfenylation and their application to monitor cisplatin induced protein oxidation, Sensors and Actuators B-chemical, Vol:248, ISSN:0925-4005, Pages:437-446

Magness AJ, Squires JA, Griffiths B, et al., 2017, Multiplexed single cell protein expression analysis in solid tumours using a miniaturised microfluidic assay, Convergent Science Physical Oncology, Vol:3, Pages:024003-024003

Lakatos E, Salehi-Reyhani A, Barclay M, et al., 2017, Protein degradation rate is the dominant mechanism accounting for the differences in protein abundance of basal p53 in a human breast and colorectal cancer cell line, Plos One, Vol:12, ISSN:1932-6203

Willison KR, Salehi-Reyhani A, Burgin E, et al., 2015, Absolute quantification of protein copy number in single cells using single molecule microarrays, European Biophysics Journal With Biophysics Letters, Vol:44, ISSN:0175-7571, Pages:S179-S179

Salehi-Reyhani A, Gesellchen F, Mampallil D, et al., 2015, Chemical-Free Lysis and Fractionation of Cells by Use of Surface Acoustic Waves for Sensitive Protein Assays, Analytical Chemistry, Vol:87, ISSN:0003-2700, Pages:2161-2169

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