Publications
400 results found
Ma D, Huang H, Zhao H, 2012, Remote Pulmonary Inflammation Following Renal Graft Engraftment In Rats, Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Publisher: MOSBY-ELSEVIER, Pages: AB162-AB162, ISSN: 0091-6749
Shu Y, Zhou Z, Wan Y, et al., 2012, Nociceptive stimuli enhance anesthetic-induced neuroapoptosis in the rat developing brain, NEUROBIOLOGY OF DISEASE, Vol: 45, Pages: 743-750, ISSN: 0969-9961
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- Citations: 82
Saczewski J, Hudson A, Laird S, et al., 2012, N-(Imidazolidin-2-ylidene)-1-arylmethanamine Oxides: Synthesis, Structure and Pharmacological Evaluation, ARCHIV DER PHARMAZIE, Vol: 345, Pages: 33-42, ISSN: 0365-6233
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- Citations: 4
Benzonana LL, Watts H, Ma D, 2012, Effects of Isoflurane on cytoskeletal re-arrangement of renal cell carcinoma cells, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Vol: 30, Pages: S28-S28, ISSN: 1107-3756
Ologunde R, Ma D, 2011, Do inhalational anesthetics cause cognitive dysfunction?, Acta Anaesthesiol Taiwan, Vol: 49, Pages: 149-153
Increasing evidence indicates that inhalational anesthetics may cause or increase the risk of developing postoperative cognitive dysfunction (POCD), especially in the elderly population. POCD may exist as a transient or long-term complication of surgery and anesthesia and is associated with reduced quality of life. There remains great discrepancy between clinical studies investigating the prevalence of POCD and inhalational anesthetics as many fail to show an association. However, numerous animal studies have suggested that inhalational anesthetics may alter cognitive function via amyloid β accumulation, modified neurotransmission, synaptic changes and dysregulated calcium homeostasis. Other factors such as neuroinflammation and pro-inflammatory cytokines may also play a role. This paper reviews the role of inhalational anesthetics in the etiology and underlying mechanisms that result in POCD.
Vizcaychipi MP, Lloyd DG, Wan Y, et al., 2011, Xenon Pretreatment May Prevent Early Memory Decline after Isoflurane Anesthesia and Surgery in Mice, PLOS ONE, Vol: 6, ISSN: 1932-6203
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- Citations: 34
Huang H, Benzonana L, Ma D, 2011, Isoflurane induced prostate cancer chemotherapy resistance <i>in vitro</i>, Conference of the Anaesthetic-Research-Society, Publisher: OXFORD UNIV PRESS, Pages: 833P-833P, ISSN: 0007-0912
Gu J, Chen J, Xia P, et al., 2011, Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice, ACTA ANAESTHESIOLOGICA SCANDINAVICA, Vol: 55, Pages: 1272-1278, ISSN: 0001-5172
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- Citations: 127
Lan F, Wang TL, Ma D, 2011, Transcutaneous electrical acupoint stimulation for pain relief and decreasing opioid-related side-effects after total hip arthroplasty in elderly patients, Conference of the Anaesthetic-Research-Society, Publisher: OXFORD UNIV PRESS, Pages: 830P-830P, ISSN: 0007-0912
Fidalgo AR, Cibelli M, White JPM, et al., 2011, PERIPHERAL ORTHOPAEDIC SURGERY DOWN-REGULATES HIPPOCAMPAL BRAIN-DERIVED NEUROTROPHIC FACTOR AND IMPAIRS REMOTE MEMORY IN MOUSE, NEUROSCIENCE, Vol: 190, Pages: 194-199, ISSN: 0306-4522
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- Citations: 25
Sanders RD, Pandharipande PP, Davidson AJ, et al., 2011, Anticipating and managing postoperative delirium and cognitive decline in adults, BMJ-BRITISH MEDICAL JOURNAL, Vol: 343, ISSN: 1756-1833
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- Citations: 91
Fidalgo AR, Cibelli M, White JPM, et al., 2011, Systemic inflammation enhances surgery-induced cognitive dysfunction in mice, NEUROSCIENCE LETTERS, Vol: 498, Pages: 63-66, ISSN: 0304-3940
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- Citations: 101
Cattano D, Valleggi S, Cavazzana AO, et al., 2011, Xenon exposure in the neonatal rat brain: effects on genes that regulate apoptosis, MINERVA ANESTESIOLOGICA, Vol: 77, Pages: 571-578, ISSN: 0375-9393
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- Citations: 19
Benzonana LL, Perry NJ, Watts HR, et al., 2011, Isoflurane increases the metastatic potential of renal cell carcinoma cells via the hypoxia inducible factor pathway- an <i>in vitro</i> study, CANCER RESEARCH, Vol: 71, ISSN: 0008-5472
Yang T, Zhuang L, Terrando N, et al., 2011, A clinically relevant model of perinatal global ischemic brain damage in rats, BRAIN RESEARCH, Vol: 1383, Pages: 317-323, ISSN: 0006-8993
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- Citations: 10
Vizcaychipi MP, Xu L, Barreto GE, et al., 2011, Heat Shock Protein 72 Overexpression Prevents Early Postoperative Memory Decline after Orthopedic Surgery under General Anesthesia in Mice, ANESTHESIOLOGY, Vol: 114, Pages: 891-900, ISSN: 0003-3022
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- Citations: 36
Benzonana LL, Perry NJS, Ma D, 2011, Potential role of the PI3K pathway on renal cell carcinoma progression <i>in vitro</i>, Annual Meeting of the Anaesthetic-Research-Society, Publisher: OXFORD UNIV PRESS, Pages: 428P-428P, ISSN: 0007-0912
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- Citations: 4
Lloyd D, Vizcaychipi M, Pac-Soo C, et al., 2011, Xenon reduces apoptosis, γ- and β-secretase expression in an <i>in vitro</i> model of Alzheimer's disease, Annual Meeting of the Anaesthetic-Research-Society, Publisher: OXFORD UNIV PRESS, Pages: 436P-436P, ISSN: 0007-0912
Zhao H, Ma D, 2011, Xenon preconditioning protects renal graft against ischaemia-reperfusion injury in rats, Annual Meeting of the Anaesthetic-Research-Society, Publisher: OXFORD UNIV PRESS, Pages: 445P-446P, ISSN: 0007-0912
Zhou Z-W, Shu Y, Li M, et al., 2011, THE GLUTAMINERGIC, GABAergic, DOPAMINERGIC BUT NOT CHOLINERGIC NEURONS ARE SUSCEPTIBLE TO ANAESTHESIA-INDUCED CELL DEATH IN THE RAT DEVELOPING BRAIN, NEUROSCIENCE, Vol: 174, Pages: 64-70, ISSN: 0306-4522
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- Citations: 34
Wang Y, Cheng X, Xu J, et al., 2011, Anti-hyperalgesic effect of CaMKII inhibitor is associated with downregulation of phosphorylated CREB in rat spinal cord, JOURNAL OF ANESTHESIA, Vol: 25, Pages: 87-92, ISSN: 0913-8668
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- Citations: 23
White JPM, Calcott G, Jenes A, et al., 2011, Xenon reduces activation of transient receptor potential vanilloid type 1 (TRPV1) in rat dorsal root ganglion cells and in human TRPV1-expressing HEK293 cells, LIFE SCIENCES, Vol: 88, Pages: 141-149, ISSN: 0024-3205
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- Citations: 5
Gu J, Sun P, Zhao H, et al., 2011, Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice, CRITICAL CARE, Vol: 15, ISSN: 1466-609X
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- Citations: 204
Saczewski J, Hudson A, Scheinin M, et al., 2011, Synthesis and Biological Activities of 2-[(Heteroaryl)methyl]imidazolines, Bioorganic & Medicinal Chemistry, Pages: ---, ISSN: 0968-0896
Pac-Soo C, Lloyd DG, Vizcaychipi MP, et al., 2011, Statins: The Role in the Treatment and Prevention of Alzheimer's Neurodegeneration, JOURNAL OF ALZHEIMERS DISEASE, Vol: 27, Pages: 1-10, ISSN: 1387-2877
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- Citations: 37
Zhang L, Huang H, Cheng J, et al., 2011, Pre-treatment with isoflurane ameliorates renal ischemic–reperfusion injury in mice, Life Sciences, Vol: 88, Pages: 1102 - 1107-1102 - 1107, ISSN: 0024-3205
Xu Y, Ma DQ, He W, et al., 2010, Computer-aided diagnosis for the detection of the pulmonary nodules on digital chest radiography in lung cancer screening, Chinese Journal of Radiology, Vol: 44, Pages: 1157-1160, ISSN: 1005-1201
Objective: To evaluate the value of computer-aided detection (CAD) system for pulmonary nodule detection using digital chest radiography in lung cancer screening. Methods: One hundred consecutive digital chest radiographs from 6280 outpatients for lung cancer screening were independently reviewed by a thoracic radiologist and a computer-aided pulmonary nodule detection system. The radiographs were also reviewed by two experienced thoracic radiologists and the true nodules confirmed by two radiologists with reference to the CT images were marked and stored as a gold standard in the CAD system The sensitivity and false positive of the radiologist and the CAD system for the detection of nodules on digital chest radiographs were compared. Results: Ninety-five and 304 nodules were identified by radiologist and the CAD system, respectively. Of 134 nodules marked as true nodules by experienced radiologists, 82 (61.2%) and 105 (78.4%) nodules were identified by the radiologist and the CAD, respectively. The radiologist missed 35 true nodules which were only detected by CAD. The CAD system missed 10 true nodules which were only detected by radiologist. One hundred and twelve (83.6%) nodules were identified by radiologist with the CAD system One hundred and ninety-nine nodules identified by CAD were false-positive with a rate of 2.0 (199/100) per case. Conclusion: Combining review of digital radiographs by radiologist with CAD system can improve the detection of pulmonary nodules in lung cancer screening.
Wan Y, Xu J, Meng F, et al., 2010, Cognitive decline following major surgery is associated with gliosis, β-amyloid accumulation, and τ phosphorylation in old mice, CRITICAL CARE MEDICINE, Vol: 38, Pages: 2190-2198, ISSN: 0090-3493
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- Citations: 124
Zhuang L, Yang T, Vizcaychipi MP, et al., 2010, ARGON PROVIDES NEUROPROTECTION AGAINST ISCHEMIA/HYPOXIA INDUCED BRAIN DAMAGE IN RAT NEONATES, 23rd Annual Meeting of the European-Society-of-Intensive-Care-Medicine, Publisher: SPRINGER, Pages: S411-S411, ISSN: 0342-4642
Penn JW, Vizcaychipi MP, Zhuang L, et al., 2010, ATORVASTATIN ATTENUATES COGNITIVE IMPAIRMENT FOLLOWING NEPHRECTOMY IN MICE, 23rd Annual Meeting of the European-Society-of-Intensive-Care-Medicine, Publisher: SPRINGER, Pages: S383-S383, ISSN: 0342-4642
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- Citations: 1
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