Imperial College London
Portrait Picture

Professor David MacIntyre

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Professor in Reproduction Systems Medicine
 
 
 
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Contact

 

+44 (0)20 7594 2195d.macintyre Website

 
 
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Location

 

Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{Holmes:2016:10.1016/B978-0-12-800344-2.00008-2,
author = {Holmes, E and MacIntyre, D and Modi, N and Marchesi, JR},
booktitle = {Metabolic Phenotyping in Personalized and Public Healthcare},
doi = {10.1016/B978-0-12-800344-2.00008-2},
pages = {213--264},
title = {Handing on health to the next generation: Early life exposures},
url = {http://dx.doi.org/10.1016/B978-0-12-800344-2.00008-2},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - CHAP
AB  - In this chapter, the role of metabolic phenotyping is described in relation to the improved understanding of the complex biochemical processes that occur in the fetus and in early life. The reasons for the importance of this type of medical supervision are discussed, and the factors that operate both in utero and in the first stages of a baby's life are given. The development of the metabolic phenotype as life begins and continues is explained, including the importance of symbiotic bacteria (the microbiome). The changing metabolic phenotyping in various conditions such as premature birth, maternal obesity, gestational diabetes, pre-eclampsia, and others is discussed in detail. Postnatal factors that influence ongoing health are then discussed in relation to metabolic processes. Finally, a strategy is proposed for monitoring infant and maternal health using metabolic phenotyping.
AU  - Holmes,E
AU  - MacIntyre,D
AU  - Modi,N
AU  - Marchesi,JR
DO  - 10.1016/B978-0-12-800344-2.00008-2
EP  - 264
PY  - 2016///
SN  - 9780128003442
SP  - 213
TI  - Handing on health to the next generation: Early life exposures
T1  - Metabolic Phenotyping in Personalized and Public Healthcare
UR  - http://dx.doi.org/10.1016/B978-0-12-800344-2.00008-2
ER  -
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