Imperial College London


Faculty of Natural SciencesDepartment of Life Sciences

Reader in Cell Cycle Control



+44 (0)20 7594 5302d.mann




605Sir Ernst Chain BuildingSouth Kensington Campus






Dr Mann's lab is interested in cancer biology, particularly that relating to cell proliferation and signal transduction. Many cancers exhibit aberrant signal transduction and the enzymes involved can make excellent targets for therapeutic intervention.  We aim to identify such targets, characterise their functions and establish techniques for regulating their activities.  For more details, click the Research tab above.


Enquiries are always welcome from individuals interested in pursuing research within our group.



Vilar R, Ruehl CL, Lim AHM, et al., 2019, An octahedral cobalt(III) complex with axial NH3 ligands that templates and selectively stabilises G-quadruplex DNA, Chemistry - a European Journal, ISSN:0947-6539

Craven G, Affron D, Raymond P, et al., 2019, Vinyl sulfonamide synthesis for irreversible tethering via a novel α-selenoether protection strategy, Medchemcomm, Vol:10, ISSN:2040-2503, Pages:158-163

Craven G, Affron D, Allen C, et al., 2018, High-throughput kinetic analysis for target-directed covalent ligand discovery, Angewandte Chemie, Vol:57, ISSN:1521-3757, Pages:5257-5261

Craven GB, Affron DP, Allen CE, et al., 2018, High-Throughput Kinetic Analysis for Target-Directed Covalent Ligand Discovery, Angewandte Chemie, Vol:130, ISSN:0044-8249, Pages:5355-5359


Mann D, Armstrong A, Craven G, et al., 2018, (WO2018033753) ASSAY, PCT/GB2017/052456

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