Imperial College London

Professor David W. McComb

Faculty of EngineeringDepartment of Materials

Adjunct Professor



+44 (0)20 7594 6750d.mccomb Website




Royal School of MinesSouth Kensington Campus






BibTex format

author = {Mccomb, DW and Lengyel, J and Carter, CB},
doi = {10.1557/mrs.2019.283},
journal = {MRS Bulletin},
pages = {924--928},
title = {Cryogenic transmission electron microscopy for materials research},
url = {},
volume = {44},
year = {2019}

RIS format (EndNote, RefMan)

AB - © Materials Research Society 2019. Cryogenic transmission electron microscopy is simply transmission electron microscopy conducted on specimens that are cooled in the microscope. The target temperature of the specimen might range from just below ambient temperature to less than 4 K. In general, as the temperature decreases, cost increases, especially below -77°C when liquid He is required. We have two reasons for wanting to cool the specimen - improving stability of the material or observing a material whose properties change at lower temperatures. Both types of study have a long history. The cause of excitement in this field today is that we have a perfect storm of research activity - electron microscopes are almost stable with minimal drift (we can correct what drift there is), we can prepare specimens from the bulk or build them up, we have spherical-aberration-corrected lenses and monochromated beams, we have direct-electron-detector cameras, and computers are becoming powerful enough to handle all the data we produce.
AU - Mccomb,DW
AU - Lengyel,J
AU - Carter,CB
DO - 10.1557/mrs.2019.283
EP - 928
PY - 2019///
SN - 0883-7694
SP - 924
TI - Cryogenic transmission electron microscopy for materials research
T2 - MRS Bulletin
UR -
VL - 44
ER -