Imperial College London

DrDannyO'Hare

Faculty of EngineeringDepartment of Bioengineering

Reader in Sensor Research
 
 
 
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Contact

 

+44 (0)20 7594 5173d.ohare

 
 
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Location

 

4.07Royal School of MinesSouth Kensington Campus

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Summary

 

Overview

 

Electrochemical sensors and biosensors for biomedical applications; lab-on-a-chip; signal processing; biofuel cells.  Target analytes include: nitric oxide, dissolved oxygen, serotonin, dopamine, pH, tissue perfusion. For more information on the work of the Biosensor Group, please click here.

Current Projects

 

Cells on chips How do cells respond in the first few minutes after stimulation with a growth factor, drug or antigen? Are there characteristic signalling and metabolic responses? We have developed biocompatible arrays of microelectrode sensors to examine the effects of angiogenin and VEG-F on aortic endothelial cells and used similar approaches to look at bacterial antigens and macrophages

The sensor array

 

dil chip

 

flow focusTPE

Microfabrication and microfluidics Sometimes it is advantageous to do bioanalysis off-line on a sample either from cells or living tissues.  Such samples are typically tiny and new approaches to analytical methods are required. We've developed chromatographic techniques on a chip and combines this with droplet flow microfluidics to act as a tiny fraction collector.droplets

Collaborators

Prof Jingoo Park, Microbiochip Center, Hanyang University, Korea

Dr Peter Cragg, School of Pharmacy, University of Brighton

Dr Rob Lammertink, Institute for Polymer Science, University of Twente, Netherlands

Prof R. Mark Wightman, Department of Chemistry, University of North Carolina, Chapel Hill

Prof Howard Stone, Department of Chemical Engineering, Harvard University

Prof Greg Swain, Department of Chemistry, State University of Michigan, East Lansing

Research Staff

Bitziou,DE

Zhao,DH

Harvey,DS

Dobson,DC

Patel,DB

Arora,DA

Research Student Supervision

Leow,PL

Kikuchi,Y

Seelanan,P

Trouillon,R