Imperial College London

Diego A. Oyarzún

Faculty of Natural SciencesDepartment of Mathematics

Research Fellow



d.oyarzun Website




6M48Huxley BuildingSouth Kensington Campus





Diego leads the Biomolecular Control Group at Imperial College, focused on the analysis and design of biochemical circuits in living cells. He holds a 2015 Young Investigator Grant from the Human Frontier Science Program and a 2013 Imperial College Research Fellowship in Biomathematics.

In 2016 he was appointed a Global Future Council Fellow by the World Economic Forum to serve in the Council on Future of Biotechnologies.

More information in his research website.

Selected Publications

Journal Articles

Weisse AY, Mannan AA, Oyarzun DA, 2016, Signaling Tug-of-War Delivers the Whole Message, Cell Systems, Vol:3, ISSN:2405-4712, Pages:414-416

Oyarzún DA, Chaves M, 2015, Design of a bistable switch to control cellular uptake, Journal of the Royal Society Interface, Vol:12, ISSN:1742-5689, Pages:20150618-20150618

Sootla A, Oyarzun D, Angeli D, et al., 2016, Shaping pulses to control bistable systems: Analysis, computation and counterexamples, Automatica, Vol:63, ISSN:0005-1098, Pages:254-264

Weiße AY, Oyarzún DA, Danos V, et al., 2015, Mechanistic links between cellular trade-offs, gene expression, and growth, Proceedings of the National Academy of Sciences of the United States of America, Vol:112, ISSN:0027-8424, Pages:E1038-E1047

Waldherr S, Oyarzún DA, Bockmayr A, 2015, Dynamic optimization of metabolic networks coupled with gene expression, Journal of Theoretical Biology, Vol:365, ISSN:0022-5193, Pages:469-485

Oyarzún DA, Bramhall JL, López-Caamal F, et al., 2014, The EGFR demonstrates linear signal transmission, Integrative Biology, Vol:6, ISSN:1757-9694, Pages:736-736

Oyarzun DA, Lugagne J-B, Stan G-BV, 2015, Noise Propagation in Synthetic Gene Circuits for Metabolic Control, Acs Synthetic Biology, Vol:4, ISSN:2161-5063, Pages:116-125

Oyarzun DA, Stan G-BV, 2013, Synthetic gene circuits for metabolic control: design trade-offs and constraints, Journal of the Royal Society Interface, Vol:10, ISSN:1742-5689

Oyarzún DA, Chaves M, Hoff-Hoffmeyer-Zlotnik M, 2012, Multistability and oscillations in genetic control of metabolism, Journal of Theoretical Biology, Vol:295, ISSN:0022-5193, Pages:139-153

Oyarzún DA, Ingalls BP, Middleton RH, et al., 2009, Sequential Activation of Metabolic Pathways: a Dynamic Optimization Approach, Bulletin of Mathematical Biology, Vol:71, ISSN:0092-8240, Pages:1851-1872

More Publications