Diego leads the Biomolecular Control Group at Imperial College, focused on the analysis and design of biochemical circuits in living cells. He holds a Young Investigator Grant from the Human Frontier Science Program and previously held a Marie Curie Fellowship and an Imperial College Research Fellowship in Biomathematics.
In 2016 Diego was appointed as Global Future Council Fellow by the World Economic Forum to serve in the Council on Future of Biotechnologies. In 2017 he was selected as one of the 100 Young Global Changers by the Think 20 Summit, mandated by the G20 presidency.
Diego also serves in the Scientific Advisory Board for the WEF Center for the Fourth Industrial Revolution in San Francisco, and most recently he was appointed to the EPSRC Early Career Forum in Mathematical Sciences.
More information in his research website.
et al., 2017, Fundamental Design Principles for Transcription-Factor-Based Metabolite Biosensors., Acs Synth Biol
Weisse AY, Mannan AA, Oyarzun DA, 2016, Signaling Tug-of-War Delivers the Whole Message, Cell Systems, Vol:3, ISSN:2405-4712, Pages:414-416
Oyarzun DA, Chaves M, 2015, Design of a bistable switch to control cellular uptake, Journal of the Royal Society Interface, Vol:12, ISSN:1742-5689
et al., 2016, Shaping pulses to control bistable systems: Analysis, computation and counterexamples, Automatica, Vol:63, ISSN:0005-1098, Pages:254-264
et al., 2015, Mechanistic links between cellular trade-offs, gene expression, and growth, Proceedings of the National Academy of Sciences of the United States of America, Vol:112, ISSN:0027-8424, Pages:E1038-E1047
Waldherr S, Oyarzun DA, Bockmayr A, 2015, Dynamic optimization of metabolic networks coupled with gene expression, Journal of Theoretical Biology, Vol:365, ISSN:0022-5193, Pages:469-485
et al., 2014, The EGFR demonstrates linear signal transmission, Integrative Biology, Vol:6, ISSN:1757-9694, Pages:736-742
Oyarzun DA, Lugagne J-B, Stan G-BV, 2015, Noise Propagation in Synthetic Gene Circuits for Metabolic Control, Acs Synthetic Biology, Vol:4, ISSN:2161-5063, Pages:116-125
et al., 2009, Sequential Activation of Metabolic Pathways: a Dynamic Optimization Approach, Bulletin of Mathematical Biology, Vol:71, ISSN:0092-8240, Pages:1851-1872
Oyarzun DA, Stan G-BV, 2013, Synthetic gene circuits for metabolic control: design trade-offs and constraints, Journal of the Royal Society Interface, Vol:10, ISSN:1742-5689
Oyarzun DA, Chaves M, Hoff-Hoffmeyer-Zlotnik M, 2012, Multistability and oscillations in genetic control of metabolism, Journal of Theoretical Biology, Vol:295, ISSN:0022-5193, Pages:139-153