Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Professor of Cardiology



+44 (0)20 7351 8810d.pennell




CMR UnitRoyal BromptonRoyal Brompton Campus






BibTex format

author = {Khalique, Z and Pennell, D},
doi = {10.1136/postgradmedj-2019-136429},
journal = {Postgraduate Medical Journal},
pages = {433--438},
title = {Diffusion tensor cardiovascular magnetic resonance.},
url = {},
volume = {95},
year = {2019}

RIS format (EndNote, RefMan)

AB - Cardiac structure and function are complex and inter-related. Current in vivo techniques assess the heart on a macroscopic scale, but a novel technique called diffusion tensor cardiovascular magnetic resonance (DT-CMR) can now assess the cardiac microstructure non-invasively. It provides information on the helical arrangement of cardiomyocytes that drives torsion and offers dynamic assessment of the sheetlets (aggregated cardiomyocytes) that rotate through the cardiac cycle to facilitate wall thickening. Through diffusion biomarkers, the expansion and organisation of the underlying myocardium can be described. DT-CMR has already identified novel microstructural abnormalities in cardiomyopathy, and ischaemic and congenital heart disease. This new knowledge supports the potential of DT-CMR to improve diagnostics and prognostication in various cardiac diseases.
AU - Khalique,Z
AU - Pennell,D
DO - 10.1136/postgradmedj-2019-136429
EP - 438
PY - 2019///
SN - 0032-5473
SP - 433
TI - Diffusion tensor cardiovascular magnetic resonance.
T2 - Postgraduate Medical Journal
UR -
UR -
UR -
UR -
VL - 95
ER -