Imperial College London

MrDuncanSpalding

Faculty of MedicineDepartment of Surgery & Cancer

Clinical Senior Lecturer in Hepato-Biliary Surgery
 
 
 
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Contact

 

+44 (0)20 3313 3941d.spalding

 
 
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Location

 

Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Reccia:2017:10.1016/j.metabol.2017.04.011,
author = {Reccia, I and Kumar, J and Akladios, C and Virdis, F and Pai, M and Habib, N and Spalding, D},
doi = {10.1016/j.metabol.2017.04.011},
journal = {Metabolism: clinical and experimental},
pages = {94--108},
title = {Non-alcoholic fatty liver disease: a sign of systemic disease},
url = {http://dx.doi.org/10.1016/j.metabol.2017.04.011},
volume = {72},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Non-alcoholic fatty liver disease (NAFLD) is the most common form of liver disease and leading cause of cirrhosis in the United States and developed countries. NAFLD is closely associated with obesity, insulin resistance and metabolic syndrome, significantly contributing to the exacerbation of the latter. Although NAFLD represents the hepatic component of metabolic syndrome, it can also be found in patients prior to their presentation with other manifestations of the syndrome. The pathogenesis of NAFLD is complex and closely intertwined with insulin resistance and obesity. Several mechanisms are undoubtedly involved in its pathogenesis and progression. In this review, we bring together the current understanding of the pathogenesis that makes NAFLD a systemic disease.
AU - Reccia,I
AU - Kumar,J
AU - Akladios,C
AU - Virdis,F
AU - Pai,M
AU - Habib,N
AU - Spalding,D
DO - 10.1016/j.metabol.2017.04.011
EP - 108
PY - 2017///
SN - 0026-0495
SP - 94
TI - Non-alcoholic fatty liver disease: a sign of systemic disease
T2 - Metabolism: clinical and experimental
UR - http://dx.doi.org/10.1016/j.metabol.2017.04.011
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000404316600011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - http://hdl.handle.net/10044/1/50652
VL - 72
ER -