I am interested in the interplay between bacteria and their host. I investigate how non-growing, persister, Salmonella can survive inside macrophages for extended periods time. Moreover, I am studying how these bacteria can withstand both immune pressure and antibiotic treatment during infection. This research is carried out in the in the lab of Dr. Sophie Helaine.
et al., 2018, Salmonella persisters undermine host immune defenses during antibiotic treatment, Science, Vol:362, ISSN:0036-8075, Pages:1156-1160
et al., 2016, Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella, Nature Microbiology, Vol:2, ISSN:2058-5276
et al., 2016, Staphylococcus aureus protects its immune-evasion proteins against degradation by neutrophil serine proteases., Cell Microbiol, Vol:18, Pages:536-545
et al., 2014, Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors., Proc Natl Acad Sci U S A, Vol:111, Pages:13187-13192