Imperial College London


Faculty of MedicineDepartment of Infectious Disease

Honorary Research Associate







Flowers buildingSouth Kensington Campus





I am interested in the interplay between bacteria and their host. I investigate how non-growing, persister, Salmonella can survive inside macrophages for extended periods time. Moreover, I am studying how these bacteria can withstand both immune pressure and antibiotic treatment during infection. This research is carried out in the in the lab of Dr. Sophie Helaine.

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Selected Publications

Journal Articles

Stapels DAC, Hill PWS, Westermann AJ, et al., 2018, Salmonella persisters undermine host immune defenses during antibiotic treatment, Science, Vol:362, ISSN:0036-8075, Pages:1156-1160

Saliba A-E, Li L, Westermann AJ, et al., 2016, Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella, Nature Microbiology, Vol:2, ISSN:2058-5276

Stapels DAC, Kuipers A, von Köckritz-Blickwede M, et al., 2016, Staphylococcus aureus protects its immune-evasion proteins against degradation by neutrophil serine proteases., Cell Microbiol, Vol:18, Pages:536-545

Stapels DAC, Ramyar KX, Bischoff M, et al., 2014, Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors., Proc Natl Acad Sci U S A, Vol:111, Pages:13187-13192

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