Imperial College London

Dr Dina Vlachou

Faculty of Natural SciencesDepartment of Life Sciences

Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 1267d.vlachou Website

 
 
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Location

 

612Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Summary

Dr Dina Vlachou is a molecular biologist with extensive experience in disease vector and parasite genetics and functional genomics. She was trained as a postdoctoral researcher on vector and parasite research in Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas (IMBB-FORTH, Crete, Greece) and the Leiden University Medical Centre (LUMC, Leiden, The Netherlands), respectively. She then joined the European Molecular Biology Laboratory (EMBL, Heidelberg, Germany) as a Marie Curie carrier development fellow to carry out research on functional genomics of mosquito/parasite interactions. She is currently Research Fellow at Imperial College London (ICL) and Adjunct Assistant Professor at the Cyprus Institute (CyI). Her research is mainly funded by the Wellcome Trust and the European Commission.


 

Selected Publications

Journal Articles

Ukegbu CV, Cho J-S, Christophides GK, et al., 2015, Transcriptional silencing and activation of paternal DNA during Plasmodium berghei zygotic development and transformation to oocyst, Cellular Microbiology, Vol:17, ISSN:1462-5814, Pages:1230-1240

Akinosoglou KA, Bushell ESC, Ukegbu CV, et al., 2015, Characterization of Plasmodium developmental transcriptomes in Anopheles gambiae midgut reveals novel regulators of malaria transmission, Cellular Microbiology, Vol:17, ISSN:1462-5814, Pages:254-268

Schlegelmilch T, Vlachou D, 2013, Cell biological analysis of mosquito midgut invasion: the defensive role of the actin-based ookinete hood, Pathogens and Global Health, Vol:107, ISSN:2047-7724, Pages:480-492

Mendes AM, Awono-Ambene PH, Nsango SE, et al., 2011, Infection Intensity-Dependent Responses of Anopheles gambiae to the African Malaria Parasite Plasmodium falciparum, Infection and Immunity, Vol:79, ISSN:0019-9567, Pages:4708-4715

Mendes AM, Schlegelmilch T, Cohuet A, et al., 2008, Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa, PLOS Pathogens, Vol:4, ISSN:1553-7366

Waterhouse RM, Kriventseva EV, Meister S, et al., 2007, Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes, Science, Vol:316, ISSN:0036-8075, Pages:1738-1743

Vlachou D, Schlegelmilch T, Runn E, et al., 2006, The developmental migration of Plasmodium in mosquitoes, Current Opinion in Genetics & Development, Vol:16, ISSN:0959-437X, Pages:384-391

Vlachou D, Kafatos FC, 2005, The complex interplay between mosquito positive and negative regulators of Plasmodium development, Current Opinion in Microbiology, Vol:8, ISSN:1369-5274, Pages:415-421

Vlachou D, Schlegelmilch T, Christophides GK, et al., 2005, Functional genomic analysis of midgut epithelial responses in Anopheles during Plasmodium invasion, Current Biology, Vol:15, ISSN:0960-9822, Pages:1185-1195

Vlachou D, Zimmermann T, Cantera R, et al., 2004, Real-time, in vivo analysis of malaria ookinete locomotion and mosquito midgut invasion, Cellular Microbiology, Vol:6, ISSN:1462-5814, Pages:671-685

Christophides GK, Vlachou D, Kafatos FC, 2004, Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae, Immunological Reviews, Vol:198, ISSN:0105-2896, Pages:127-148

Christophides GK, Zdobnov E, Barillas-Mury C, et al., 2002, Immunity-related genes and gene families in Anopheles gambiae, Science, Vol:298, ISSN:0036-8075, Pages:159-165

Vlachou D, Lycett G, Siden-Kiamos I, et al., 2001, Anopheles gambiae laminin interacts with the P25 surface protein of Plasmodium berghei ookinetes, Molecular and Biochemical Parasitology, Vol:112, ISSN:0166-6851, Pages:229-237

Siden-Kiamos I, Vlachou D, Margos G, et al., 2000, Distinct roles for Pbs21 and Pbs25 in the in vitro ookinete to oocyst transformation of Plasmodium berghei, Journal of Cell Science, Vol:113, ISSN:0021-9533, Pages:3419-3426

Vlachou D, Konsolaki M, Tolias PP, et al., 1997, The autosomal chorion locus of the medfly Ceratitis capitata .1. Conserved synteny, amplification and tissue specificity but sequence divergence and altered temporal regulation, Genetics, Vol:147, ISSN:0016-6731, Pages:1829-1842

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