Imperial College London

Professor Dale Wigley FRS

Faculty of MedicineDepartment of Medicine

Chair in Protein Crystallography
 
 
 
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Contact

 

+44 (0)20 7594 8417d.wigley

 
 
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Assistant

 

Mrs Kasia Pearce +44 (0)20 7594 2763

 
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Location

 

258Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

13 results found

Willhoft O, Ghoneim M, Lin C-L, Chua EYD, Wilkinson M, Chaban Y, Ayala R, McCormack EA, Ocloo L, Rueda DS, Wigley DBet al., 2018, Structure and dynamics of the yeast SWR1-nucleosome complex, SCIENCE, Vol: 362, Pages: 199-+, ISSN: 0036-8075

JOURNAL ARTICLE

Ayala R, Willhoft O, Aramayo RJ, Wilkinson M, McCormack EA, Ocloo L, Wigley DB, Zhang Xet al., 2018, Structure and regulation of the human INO80-nucleosome complex, NATURE, Vol: 556, Pages: 391-+, ISSN: 0028-0836

JOURNAL ARTICLE

Aramayo RJ, Willhoft O, Ayala R, Bythell-Douglas R, Wigley DB, Zhang Xet al., 2018, Cryo-EM structures of the human INO80 chromatin-remodeling complex, NATURE STRUCTURAL & MOLECULAR BIOLOGY, Vol: 25, Pages: 37-+, ISSN: 1545-9993

JOURNAL ARTICLE

Lin C-L, Chaban Y, Rees DM, McCormack EA, Ocloo L, Wigley DBet al., 2017, Functional characterization and architecture of recombinant yeast SWR1 histone exchange complex, Nucleic Acids Research, Vol: 45, Pages: 7249-7260, ISSN: 0305-1048

JOURNAL ARTICLE

Willhoft O, McCormack EA, Aramayo RJ, Bythell-Douglas R, Ocloo L, Zhang X, Wigley DBet al., 2017, Crosstalk within a functional INO80 complex dimer regulates nucleosome sliding, ELIFE, Vol: 6, ISSN: 2050-084X

JOURNAL ARTICLE

Sanders K, Lin C-L, Smith AJ, Cronin N, Fisher G, Eftychidis V, McGlynn P, Savery NJ, Wigley DB, Dillingham MSet al., 2017, The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase, Nucleic Acids Research, Vol: 45, Pages: 3875-3887, ISSN: 0305-1048

JOURNAL ARTICLE

Rees DM, Willhoft O, Lin C-L, Bythell-Douglas R, Wigley DBet al., 2017, Production and Assay of Recombinant Multisubunit Chromatin Remodeling Complexes, DNA REPAIR ENZYMES: STRUCTURE, BIOPHYSICS, AND MECHANISM, Vol: 592, Pages: 27-47, ISSN: 0076-6879

JOURNAL ARTICLE

Wilkinson M, Troman L, Wan Nur Ismah WAK, Chaban Y, Avison MB, Dillingham MS, Wigley DBet al., 2016, Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones, eLife, Vol: 5

JOURNAL ARTICLE

Willhoft O, Bythell-Douglas R, McCormack EA, Wigley DBet al., 2016, Synergy and antagonism in regulation of recombinant human INO80 chromatin remodeling complex, NUCLEIC ACIDS RESEARCH, Vol: 44, Pages: 8179-8188, ISSN: 0305-1048

JOURNAL ARTICLE

Wilkinson M, Chaban Y, Wigley DB, 2016, Mechanism for nuclease regulation in RecBCD, eLife, Vol: 5

JOURNAL ARTICLE

Krajewski WW, Fu X, Wilkinson M, Cronin NB, Dillingham MS, Wigley DBet al., 2014, Structural basis for translocation by AddAB helicase–nuclease and its arrest at χ sites, Nature, Vol: 508, Pages: 416-419, ISSN: 0028-0836

JOURNAL ARTICLE

Saravanan M, Wuerges J, Bose D, McCormack EA, Cook NJ, Zhang X, Wigley DBet al., 2012, Interactions between the nucleosome histone core and Arp8 in the INO80 chromatin remodeling complex, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 109, Pages: 20883-20888, ISSN: 0027-8424

JOURNAL ARTICLE

Zhang X, Wigley DB, 2008, The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA plus proteins, NATURE STRUCTURAL & MOLECULAR BIOLOGY, Vol: 15, Pages: 1223-1227, ISSN: 1545-9993

JOURNAL ARTICLE

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