Imperial College London

Professor Dan Elson

Faculty of MedicineDepartment of Surgery & Cancer

Professor of Surgical Imaging
 
 
 
//

Contact

 

+44 (0)20 7594 1700daniel.elson Website

 
 
//

Location

 

415 Bessemer BuildingBessemer BuildingSouth Kensington Campus

//

Summary

 

Publications

Publication Type
Year
to

377 results found

Elson DS, 2014, CLEO: Applications and Technology, Laser Europe: Clinical and Scientific PDT and Biophotonics

Conference paper

Singh M, Harris-Birtill D, Gallina M, Zhou Y, Cass T, Hanna G, Elson DSet al., 2014, Application of Gold Nanorods for Photothermal Effect in Upper Gastrointestinal Cancer Tissue., International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Publisher: ASGBI

Conference paper

Clancy N, Arya S, Corbett R, Singh M, Stoyanov D, Crane J, Duncan N, Ebner M, Caro C, Hanna G, Elson DSet al., 2014, Optical Measurement of Anastomotic Oxygenation Dynamics, Biomedical Optics Topical Meeting, Publisher: Optical Society of America

Conference paper

Li S, Cheng Y, Song L, Eckersley RJ, Elson DS, Tang M-Xet al., 2014, Tracking shear waves in turbid medium by light: theory, simulation, and experiment, OPTICS LETTERS, Vol: 39, Pages: 1597-1600, ISSN: 0146-9592

Journal article

Yankelevich DR, Ma D, Liu J, Sun Y, Sun Y, Bec J, Elson DS, Marcu Let al., 2014, Design and evaluation of a device for fast multispectral time-resolved fluorescence spectroscopy and imaging, REVIEW OF SCIENTIFIC INSTRUMENTS, Vol: 85, ISSN: 0034-6748

Journal article

Qi J, Clancy N, Singh M, Elson DSet al., 2014, Endoscopic 3x3 and 4x4 Mueller Matrix polarimetric tissue imaging system, BIOS - Advanced Biomedical and Clinical Diagnostic Systems XII

Conference paper

Li S, Cheng Y, Eckersley RJ, Elson DS, Tang MXet al., 2014, Simulation and optimization of shear wave detection by laser speckle contrast analysis for cm-depth elasticity imaging, BIOS - Optical Elastography and Tissue Biomechanics, Publisher: SPIE

Conference paper

French PMW, 2014, Fluorescence Lifetime Imaging for Biomedicine, 2014 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO), ISSN: 2160-9020

Journal article

Elson DS, Marcu L, French PMW, 2014, Overview of fluorescence lifetime imaging and metrology, ISBN: 9781439861677

© 2015 by Taylor & Francis Group, LLC. This chapter aims to present an overview of fluorescence lifetime imaging (FLIM) and metrology in the context of their biomedical applications, introducing the main approaches that are discussed in detail in subsequent chapters of this book. Before discussing fluorescence lifetime measurements, however, it is important to understand the phenomenon of fluorescence, of which a brief discussion is provided here, and the reader is directed to the classic textbook by Lakowicz (1999) for further details.

Book

Su L, Fonseca MB, Arya S, Kudo H, Goldin R, Hanna GB, Elson DSet al., 2014, Laser-induced tissue fluorescence in radiofrequency tissue-fusion characterization, JOURNAL OF BIOMEDICAL OPTICS, Vol: 19, ISSN: 1083-3668

Journal article

Clancy NT, Saso S, Stoyanov D, Sauvage V, Corless DJ, Boyd M, Noakes DE, Thum M-Y, Ghaem-Maghami S, Smith JR, Elson DSet al., 2014, Multispectral Imaging of Organ Viability during Uterine Transplantation Surgery, Conference on Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XII, Publisher: SPIE-INT SOC OPTICAL ENGINEERING, ISSN: 0277-786X

Conference paper

Marcu L, French PMW, Elson DS, 2014, Preface, ISBN: 9781439861677

© 2015 by Taylor & Francis Group, LLC. Wide-field time-gated fluorescence lifetime imaging (FLIM) essentially entails illuminating a sample with an ultrashort pulse of excitation radiation and sampling the resulting time varying fluorescence “image” following excitation by acquiring a series of gated fluorescence intensity images recorded at different relative delays with respect to the excitation pulse. This is represented schematically in Figure 8.1. In the simplest case, a map of the mean fluorescence decay times across the field of view is obtained. If the sampling of the fluorescence decay profiles is appropriately detailed, then the entire fluorescence decay profile for each image pixel can be acquired, and the resulting data set can be fitted to complex temporal decay models. For example, a double exponential decay model is frequently used to analyze data from Förster resonant energy transfer (FRET) experiments. The acquisition of time-gated fluorescence intensity images requires a 2-D detector, normally a charge-coupled device (CCD) camera, and some kind of fast “shutter” able to sample fluorescence decay profiles on subnanosecond timescales. Such a “shutter” function cannot be provided by mechanical means or yet by electronic circuitry and is typically provided by optical image intensifiers whose gain can be modulated by varying the applied voltage.

Book

Singh M, Harris-Birtill D, Gallina M, Hanna G, Elson DSet al., Application of Gold Nanorods for Photothermal Effect in Upper Gastrointestinal Cancer Tissue, International Surgical Congress of the Association of Surgeons of Great Britain and Ireland

Conference paper

Harris-Birtill D, Singh M, Zhou Y, Elena-Gallina M, Cass T, Elson Det al., 2014, Gold Nanorod Reshaping using a Continuous Wave Laser

Gold nanorods for photothermal therapy are shown, using spectroscopy and electron microscopy, to reshape after irradiation with a 6W/cm2 continuous wave laser, affecting their absorption coefficient and thus their clinical efficacy. © 2014 OSA.

Conference paper

Harris-Birtill D, Singh M, Zhou Y, Elena-Gallina M, Cass T, Elson Det al., 2014, Gold nanorod reshaping using a continuous wave laser

Gold nanorods for photothermal therapy are shown, using spectroscopy and electron microscopy, to reshape after irradiation with a 6W/cm2 continuous wave laser, affecting their absorption coefficient and thus their clinical efficacy. © 2014 OSA.

Conference paper

Jones G, Clancy N, Arridge S, Elson D, Stoyanov Det al., 2014, Deblurring multispectral laparoscopic images, Pages: 216-225, ISSN: 0302-9743

Multispectral imaging is an optical modality that can provide real-time in vivo information about tissue characteristics and function through signal sensitivity to chromophores in the tissue. In this paper, we present a deblurring strategy that enables imaging of dynamic tissues at wavelengths where the required acquisition time can cause significant motion blur and obscure the image. We use deconvolution for spatially varying kernels to process multispectral information obtained by using a novel laparoscopic imaging device. The trinocular design of the system allows visible light images provide information about the tissue morphology and motion that we use to construct a per pixel deformation map. We demonstrate that with the proposed method the multispectral image stack can be synthesised into a meaningful signal even in the presence of significant tissue motion. Experiments on synthetic data validate the numerical properties of the method and experiments with ex vivo tissue demonstrate the practical potential of the technique. © 2014 Springer International Publishing Switzerland.

Conference paper

Qi J, Singh M, Clancy N, Elson Det al., 2014, Mueller polarimetric endoscopy

Mueller polarimetric imaging is a promising technique which is able to provide additional polarisation contrast for surgical imaging. In this work, an improved 3×3 Mueller matrix and a 4×4 Mueller matrix endoscopic system were constructed and images of rat abdomen were obtained and decomposed to quantify depolarisation, diattenuation and linear retardance. © 2014 OSA.

Conference paper

Avila-Rencoret F, Mylonas G, Elson DS, 2014, A Novel Endoscopic Scanning-Probe Device for Rapid Screening of Gastrointestinal Dysplasia, Publisher: The Bioengineering Society

Conference paper

Maier-Hein L, Mountney P, Bartoli A, Elhawary H, Elson D, Groch A, Kolb A, Rodrigues M, Sorger J, Speidel S, Stoyanov Det al., 2013, Optical techniques for 3D surface reconstruction in computer-assisted laparoscopic surgery, MEDICAL IMAGE ANALYSIS, Vol: 17, Pages: 974-996, ISSN: 1361-8415

Journal article

Cheng Y, Li S, Eckersley RJ, Elson DS, Tang M-Xet al., 2013, Viscosity measurement based on shear-wave laser speckle contrast analysis, JOURNAL OF BIOMEDICAL OPTICS, Vol: 18, ISSN: 1083-3668

Journal article

Tziraki M, Song L, Clancy NT, Saso S, Corless DJ, Boyd M, Noakes DE, Ghaem-Maghami S, Smith RJ, Elson DSet al., 2013, Endoscopic Laser Speckle Contrast Analysis (ELASCA) for measuring blood flow during uterine transplant surgery, Optics in Clinical Practice II, Publisher: Institute of Physics

Conference paper

Qi J, Ye M, Singh M, Clancy NT, Elson DSet al., 2013, Narrow band 3 x 3 Mueller polarimetric endoscopy, BIOMEDICAL OPTICS EXPRESS, Vol: 4, Pages: 2433-2449, ISSN: 2156-7085

Journal article

Cheng Y, Li S, Eckersley RJ, Elson DS, Tang M-Xet al., 2013, Shear wave viscoelasticity measurement by laser speckle contrast detection, International Tissue Elasticity Conference

Conference paper

Gallina ME, Zhou Y, Johnson CJ, Harris-Birtill D, Cass T, Elson DSet al., 2013, Synthesis and Bioconjugation of Multifunctional Gold Nanorods for Specific Targeting and Photothermal Therapy of Cancer Cells, Bio-Nano-Photonics 2013

Conference paper

Harris-Birtill D, Gallina ME, Zhou Y, Singh M, Cass T, Elson DSet al., 2013, Automatic image analysis of nanorod dimensions, Bio-Nano-Photonics 2013

Conference paper

Singh M, Harris-Birtill D, Gallina ME, Zhou Y, Cass T, Hanna G, Elson DSet al., 2013, Application of Gold Nanorods for Photothermal Effect in Upper Gastrointestinal Cancer Tissue, 7th London Surgical Symposium & 66th Simpson Smith Lecture and Awards

Conference paper

Arya S, Hadjievangelou N, Lei S, Kudo H, Goldin RD, Darzi AW, Elson DS, Hanna GBet al., 2013, Radiofrequency-induced small bowel thermofusion: an ex vivo study of intestinal seal adequacy using mechanical and imaging modalities, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 27, Pages: 3485-3496, ISSN: 0930-2794

Journal article

Sun Y, Phipps JE, Meier J, Hatami N, Poirier B, Elson DS, Farwell DG, Marcu Let al., 2013, Endoscopic Fluorescence Lifetime Imaging for In Vivo Intraoperative Diagnosis of Oral Carcinoma, MICROSCOPY AND MICROANALYSIS, Vol: 19, Pages: 791-798, ISSN: 1431-9276

Journal article

Cheng Y, Li S, Elson DS, Tang MXet al., 2013, Observation of shear wave dispersion based on optical detection, International Ultrasonic Symposium, Publisher: IEEE

Conference paper

Clancy NT, Ebner M, Crane JS, Corbett R, Duncan N, Caro C, Elson DSet al., 2013, Multispectral Imaging using a Fast Filter Wheel System during Vascular Surgery, The Hamlyn Symposium on Medical Robotics, Pages: 69-70

Conference paper

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00302438&limit=30&person=true&page=6&respub-action=search.html