Imperial College London

Professor Dan Elson

Faculty of MedicineDepartment of Surgery & Cancer

Professor of Surgical Imaging



+44 (0)20 7594 1700daniel.elson Website




415 Bessemer BuildingBessemer BuildingSouth Kensington Campus






BibTex format

author = {Li, Q and Lin, J and Clancy, NT and Elson, DS},
doi = {10.1007/s11548-019-01940-2},
journal = {International Journal of Computer Assisted Radiology and Surgery},
pages = {987--995},
title = {Estimation of tissue oxygen saturation from RGB images and sparse hyperspectral signals based on conditional generative adversarial network},
url = {},
volume = {14},
year = {2019}

RIS format (EndNote, RefMan)

AB - Purpose: Intra-operative measurement of tissue oxygen saturation (StO 2 ) is important in detection of ischaemia, monitoring perfusion and identifying disease. Hyperspectral imaging (HSI) measures the optical reflectance spectrum of the tissue and uses this information to quantify its composition, including StO 2 . However, real-time monitoring is difficult due to capture rate and data processing time. Methods: An endoscopic system based on a multi-fibre probe was previously developed to sparsely capture HSI data (sHSI). These were combined with RGB images, via a deep neural network, to generate high-resolution hypercubes and calculate StO 2 . To improve accuracy and processing speed, we propose a dual-input conditional generative adversarial network, Dual2StO2, to directly estimate StO 2 by fusing features from both RGB and sHSI. Results: Validation experiments were carried out on in vivo porcine bowel data, where the ground truth StO 2 was generated from the HSI camera. Performance was also compared to our previous super-spectral-resolution network, SSRNet in terms of mean StO 2 prediction accuracy and structural similarity metrics. Dual2StO2 was also tested using simulated probe data with varying fibre number. Conclusions: StO 2 estimation by Dual2StO2 is visually closer to ground truth in general structure and achieves higher prediction accuracy and faster processing speed than SSRNet. Simulations showed that results improved when a greater number of fibres are used in the probe. Future work will include refinement of the network architecture, hardware optimization based on simulation results, and evaluation of the technique in clinical applications beyond StO 2 estimation.
AU - Li,Q
AU - Lin,J
AU - Clancy,NT
AU - Elson,DS
DO - 10.1007/s11548-019-01940-2
EP - 995
PY - 2019///
SN - 1861-6410
SP - 987
TI - Estimation of tissue oxygen saturation from RGB images and sparse hyperspectral signals based on conditional generative adversarial network
T2 - International Journal of Computer Assisted Radiology and Surgery
UR -
UR -
VL - 14
ER -