Publications
300 results found
Avila Rencoret FB, Elson D, Mylonas G, A Robotic Hyperspectral Scanning Framework for Endoscopy, CRAS - Workshop on Computer/Robot Assisted Surgery
Gastrointestinal (GI) endoscopy is the gold-standard procedure for detection and treatment of dysplastic lesions and early stage GI cancers. Despite its proven effectiveness, its sensitivity remains suboptimal due to the subjective nature of the examination, which is substantially reliant on human-operator skills. For bowel cancer, colonoscopy can miss up to 22% of dysplastic lesions, with even higher miss rates for small (<5 mm diameter) and flat lesions. We propose a robotic hyperspectral (HS) scanning framework that aims to improve the sensitivity of GI endoscopy by automated scanning and real-time classification of wide tissue areas based on their HS features. A “hot-spot” map is generated to highlight dysplastic or cancerous lesions for further scrutiny or concurrent resection. The device works as an add-on accessory to any conventional endoscope, and to our knowledge, is the first of its kind. This paper focuses on characterising its optical resolution on rigid and deformable colon phantoms. We report for the first time 2D and 3D wide-area reconstruction of endoscopic HS data with sub-millimetre optical resolution. The current setup, compatible with the anatomical dimensions of the colon, could allow the identification of flat and small pre-cancerous lesions that are currently missed. The proposed framework will lay the foundations towards the next generation of augmented reality endoscopy while increasing its sensitivity and specificity.
Avila-Rencoret F, Oude Vrielink T, Elson DS, et al., EndoSDR: Concurrent Endoscopic Screening, Diagnosis, and Removal of GI cancers (prize winner), Business Engineering and Surgical Technologies Innovation Symposium (BEST)
Elson DS, Surgical Imaging, Biophotonics and Endoscopy (keynote), International Conference on Biomedical Engineering and Biophysics
Elson DS, Application of Targeted Fluorescent Gold Nanorods for Image Guided Cancer Thermal Therapy (invited), OSA Topical Meetings, Biomedical Optics
Elson DS, Surgical endoscopy, vision and bio-photonics, Royal Society International Scientific Seminar: Imaging in Graphics, Vision and Beyond
Elson DS, He C, Qi J, A real time complete Stokes polarimetric imager based on a linear polarizerarray camera for tissue polarimetric imaging, Biomedical Optics Express, ISSN: 2156-7085
Elson DS, Song L, Wang X, et al., Laser speckle contrast analysis for measuring tissue perfusion (invited), Optoelectronic Global Conference 2015
Elson D S, Poher V, Hares J, et al., Fluorescence lifetime imaging (FLIM) in the time and frequency domains using a low cost LED, Photonex, Publisher: Institute of Physics
Harris-Birtill D, Singh M, Zhou YU, et al., Gold Nanorod Reshaping using a Continuous Wave Laser, Bio-Nano-Photonics Symposium
Jones G, Clancy NT, Arridge S, et al., Inference of Tissue Haemoglobin Concentration From Stereo RGB, 7th International Conference on Medical Imaging and Augmented Reality
Lin J, Clancy NT, Elson DS, An endoscopic structured light system using multispectral detection, International Conference on Information Processing and Computer Assisted Interventions
Lin J, Clancy NT, Sun X, et al., Hybrid Tissue Surface Hyperspectral imaging and Shape Recovery, Hyperspectral Imaging & Applications Conference
Lin J, Clancy NT, Sun X, et al., Probe-based Rapid Hybrid Hyperspectral and Tissue Surface Imaging Aided by Fully Convolutional Networks, Medical Image Computing and Computer Assisted Intervention (MICCAI)
Nabavi E, Singh M, Zhou Y, et al., Preliminary studies of targeted NIR photothermal therapy of human oesophageal adenocarcinoma in mice using multifunctional GNRs, British Medical Laser Association Conference
Qi J, Elson DS, A high definition Mueller polarimetric endoscope for tissue characterisation, BIOS - Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
Qi J, Elson DS, Polarimetric rigid endoscopes for tissue imaging, 2nd Workshop of the European Industrial Doctorate
Qi J, Singh M, Pigula A, et al., Rigid endoscopic polarimetric wide-field imaging (invited), SPIE BiOS Molecular-Guided Surgery
Saso S, Clancy N, Jones B, et al., Assessing uterine graft viability using multispectral imaging during uterine transplantation, 25th World Congress on Ultrasound in Obstetrics and Gynecology
Saso S, Clancy N, Tziraki M, et al., Use of endoscopic laser speckle contrast analysis to assess uterine perfusion and blood flow in a uterine transplantation model, 25th World Congress on Ultrasound in Obstetrics and Gynecology
Singh M, Harris-Birtill D, Gallina M, et al., Application of Gold Nanorods for Photothermal Effect in Upper Gastrointestinal Cancer Tissue, International Surgical Congress of the Association of Surgeons of Great Britain and Ireland
Singh M, Nabavi E, Zhou Y, et al., Application of Gold Nanoparticles for Photothermal Therapy of Upper Gastrointestinal Adenocarcinoma, Bio-Nano-Photonics Symposium
Singh M, Nabavi E, Zhou Y, et al., Application of Gold Nanorods in Cancer Theranostics (plenary presentation winner), Society for Surgery of the Alimentary Tract Annual Meeting, 31st Annual SSAT Residents and Fellows Research Conference
Tatla T, Sparks H, Charn T, et al., Development of endoscopic fluorescence lifetime imaging microscopy (FLIM) for head and neck squamous cell cancer (HNSCC) screening: sub-site ex vivo data analysis, Head and Neck Optical Diagnostic Society Annual Meeting
Wirkert S, Kenngott H, Mayer B, et al., Robust near real-time estimation of physiological parameters from megapixel multispectral images with inverse Monte Carlo and random forest regression, Information Processing in Comupter Aided Intervention
Clancy NT, Elson DS, Teare J, 2017, Hyperspectral imaging of colonic polyps in vivo (Conference Presentation), Conference on Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV, Publisher: SPIE-INT SOC OPTICAL ENGINEERING, ISSN: 0277-786X
Dong Y, Qi J, He H, et al., 2017, Quantitatively characterizing the microstructural features of breast ductal carcinoma tissues in different progression stages by Mueller matrix microscope, BIOMEDICAL OPTICS EXPRESS, Vol: 8, Pages: 3643-3655, ISSN: 2156-7085
Janatka M, Ramdoo KS, Tatla T, et al., 2017, Examining in vivo Tympanic Membrane Mobility Using Smart Phone Video-Otoscopy and Phase-based Eulerian Video Magnification, Conference on Medical Imaging - Computer-Aided Diagnosis, Publisher: SPIE-INT SOC OPTICAL ENGINEERING, ISSN: 0277-786X
Jones G, Clancy NT, Helo Y, et al., 2017, Bayesian Estimation of Intrinsic Tissue Oxygenation and Perfusion From RGB Images, IEEE TRANSACTIONS ON MEDICAL IMAGING, Vol: 36, Pages: 1491-1501, ISSN: 0278-0062
Qi J, Elson DS, 2017, Mueller polarimetric imaging for surgical and diagnostic applications: a review, JOURNAL OF BIOPHOTONICS, Vol: 10, Pages: 950-982, ISSN: 1864-063X
Shah PL, Kemp SV, Newton RC, et al., 2017, Clinical Correlation between Real-Time Endocytoscopy, Confocal Endomicroscopy, and Histopathology in the Central Airways, RESPIRATION, Vol: 93, Pages: 51-57, ISSN: 0025-7931
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.