Publications
505 results found
Harris-Birtill D, Singh M, Zhou Y, et al., 2014, Gold Nanorod Reshaping using a Continuous Wave Laser, CLEO: Applications and Technology, Publisher: Optical Society of America
Qi J, Singh M, Clancy N, et al., 2014, Mueller polarimetric endoscopy, CLEO: Applications and Technology, Publisher: Optical Society of America
Elson DS, 2014, CLEO: Applications and Technology, Laser Europe: Clinical and Scientific PDT and Biophotonics
Jones G, Clancy N, Arridge S, et al., 2014, Deblurring multispectral laparoscopic images, IPCAI 2014, Publisher: Springer International Publishing, Pages: 216-225, ISSN: 0302-9743
Multispectral imaging is an optical modality that can provide real-time in vivo information about tissue characteristics and function through signal sensitivity to chromophores in the tissue. In this paper, we present a deblurring strategy that enables imaging of dynamic tissues at wavelengths where the required acquisition time can cause significant motion blur and obscure the image. We use deconvolution for spatially varying kernels to process multispectral information obtained by using a novel laparoscopic imaging device. The trinocular design of the system allows visible light images provide information about the tissue morphology and motion that we use to construct a per pixel deformation map. We demonstrate that with the proposed method the multispectral image stack can be synthesised into a meaningful signal even in the presence of significant tissue motion. Experiments on synthetic data validate the numerical properties of the method and experiments with ex vivo tissue demonstrate the practical potential of the technique.
Singh M, Harris-Birtill D, Gallina M, et al., 2014, Application of Gold Nanorods for Photothermal Effect in Upper Gastrointestinal Cancer Tissue., International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Publisher: ASGBI
Clancy N, Arya S, Corbett R, et al., 2014, Optical measurement of anastomotic oxygenation dynamics, Biomedical Optics Topical Meeting, Publisher: Optical Society of America
Li S, Cheng Y, Song L, et al., 2014, Tracking shear waves in turbid medium by light: theory, simulation, and experiment, OPTICS LETTERS, Vol: 39, Pages: 1597-1600, ISSN: 0146-9592
- Author Web Link
- Open Access Link
- Cite
- Citations: 8
Yankelevich DR, Ma D, Liu J, et al., 2014, Design and evaluation of a device for fast multispectral time-resolved fluorescence spectroscopy and imaging, REVIEW OF SCIENTIFIC INSTRUMENTS, Vol: 85, ISSN: 0034-6748
- Author Web Link
- Open Access Link
- Cite
- Citations: 70
Li S, Cheng Y, Eckersley RJ, et al., 2014, Simulation and optimization of shear wave detection by laser speckle contrast analysis for cm-depth elasticity imaging, BIOS - Optical Elastography and Tissue Biomechanics, Publisher: SPIE
Qi J, Clancy N, Singh M, et al., 2014, Endoscopic 3x3 and 4x4 Mueller Matrix polarimetric tissue imaging system, BIOS - Advanced Biomedical and Clinical Diagnostic Systems XII
Harris-Birtill D, Singh M, Zhou Y, et al., 2014, Gold nanorod reshaping using a continuous wave laser
Gold nanorods for photothermal therapy are shown, using spectroscopy and electron microscopy, to reshape after irradiation with a 6W/cm2 continuous wave laser, affecting their absorption coefficient and thus their clinical efficacy. © 2014 OSA.
Qi J, Singh M, Clancy N, et al., 2014, Mueller polarimetric endoscopy
Mueller polarimetric imaging is a promising technique which is able to provide additional polarisation contrast for surgical imaging. In this work, an improved 3×3 Mueller matrix and a 4×4 Mueller matrix endoscopic system were constructed and images of rat abdomen were obtained and decomposed to quantify depolarisation, diattenuation and linear retardance. © 2014 OSA.
Elson DS, Marcu L, French PMW, 2014, Overview of fluorescence lifetime imaging and metrology, ISBN: 9781439861677
This chapter aims to present an overview of fluorescence lifetime imaging (FLIM) and metrology in the context of their biomedical applications, introducing the main approaches that are discussed in detail in subsequent chapters of this book. Before discussing fluorescence lifetime measurements, however, it is important to understand the phenomenon of fluorescence, of which a brief discussion is provided here, and the reader is directed to the classic textbook by Lakowicz (1999) for further details.
Qi J, Singh M, Clancy N, et al., 2014, Mueller polarimetric endoscopy
Mueller polarimetric imaging is a promising technique which is able to provide additional polarisation contrast for surgical imaging. In this work, an improved 3×3 Mueller matrix and a 4×4 Mueller matrix endoscopic system were constructed and images of rat abdomen were obtained and decomposed to quantify depolarisation, diattenuation and linear retardance. © 2014 OSA.
Harris-Birtill D, Singh M, Zhou Y, et al., 2014, Gold nanorod reshaping using a continuous wave laser
Gold nanorods for photothermal therapy are shown, using spectroscopy and electron microscopy, to reshape after irradiation with a 6W/cm2 continuous wave laser, affecting their absorption coefficient and thus their clinical efficacy. © 2014 OSA.
Harris-Birtill D, Singh M, Zhou Y, et al., 2014, Gold Nanorod Reshaping using a Continuous Wave Laser
Gold nanorods for photothermal therapy are shown, using spectroscopy and electron microscopy, to reshape after irradiation with a 6W/cm2 continuous wave laser, affecting their absorption coefficient and thus their clinical efficacy. © 2014 OSA.
Singh M, Harris-Birtill D, Gallina M, et al., 2014, Application of Gold Nanorods for Photothermal Effect in Upper Gastrointestinal Cancer Tissue, International Surgical Congress of the Association of Surgeons of Great Britain and Ireland
Marcu L, French PMW, Elson DS, 2014, Preface, ISBN: 9781439861677
Wide-field time-gated fluorescence lifetime imaging (FLIM) essentially entails illuminating a sample with an ultrashort pulse of excitation radiation and sampling the resulting time varying fluorescence “image” following excitation by acquiring a series of gated fluorescence intensity images recorded at different relative delays with respect to the excitation pulse. This is represented schematically in Figure 8.1. In the simplest case, a map of the mean fluorescence decay times across the field of view is obtained. If the sampling of the fluorescence decay profiles is appropriately detailed, then the entire fluorescence decay profile for each image pixel can be acquired, and the resulting data set can be fitted to complex temporal decay models. For example, a double exponential decay model is frequently used to analyze data from Förster resonant energy transfer (FRET) experiments. The acquisition of time-gated fluorescence intensity images requires a 2-D detector, normally a charge-coupled device (CCD) camera, and some kind of fast “shutter” able to sample fluorescence decay profiles on subnanosecond timescales. Such a “shutter” function cannot be provided by mechanical means or yet by electronic circuitry and is typically provided by optical image intensifiers whose gain can be modulated by varying the applied voltage.
Su L, Fonseca MB, Arya S, et al., 2014, Laser-induced tissue fluorescence in radiofrequency tissue-fusion characterization, JOURNAL OF BIOMEDICAL OPTICS, Vol: 19, ISSN: 1083-3668
- Author Web Link
- Open Access Link
- Cite
- Citations: 12
Clancy NT, Saso S, Stoyanov D, et al., 2014, Multispectral Imaging of Organ Viability during Uterine Transplantation Surgery, Conference on Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XII, Publisher: SPIE-INT SOC OPTICAL ENGINEERING, ISSN: 0277-786X
- Author Web Link
- Open Access Link
- Cite
- Citations: 8
Avila-Rencoret F, Mylonas G, Elson DS, 2014, A Novel Endoscopic Scanning-Probe Device for Rapid Screening of Gastrointestinal Dysplasia, Publisher: The Bioengineering Society
French PMW, 2014, Fluorescence Lifetime Imaging for Biomedicine, 2014 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO), ISSN: 2160-9020
- Author Web Link
- Cite
- Citations: 1
Cheng Y, Li S, Eckersley RJ, et al., 2013, Viscosity measurement based on shear-wave laser speckle contrast analysis, JOURNAL OF BIOMEDICAL OPTICS, Vol: 18, ISSN: 1083-3668
- Author Web Link
- Open Access Link
- Cite
- Citations: 7
Maier-Hein L, Mountney P, Bartoli A, et al., 2013, Optical techniques for 3D surface reconstruction in computer-assisted laparoscopic surgery, MEDICAL IMAGE ANALYSIS, Vol: 17, Pages: 974-996, ISSN: 1361-8415
- Author Web Link
- Open Access Link
- Cite
- Citations: 178
Tziraki M, Song L, Clancy NT, et al., 2013, Endoscopic Laser Speckle Contrast Analysis (ELASCA) for measuring blood flow during uterine transplant surgery, Optics in Clinical Practice II, Publisher: Institute of Physics
Qi J, Ye M, Singh M, et al., 2013, Narrow band 3 x 3 Mueller polarimetric endoscopy, BIOMEDICAL OPTICS EXPRESS, Vol: 4, Pages: 2433-2449, ISSN: 2156-7085
- Author Web Link
- Open Access Link
- Cite
- Citations: 61
Cheng Y, Li S, Eckersley RJ, et al., 2013, Shear wave viscoelasticity measurement by laser speckle contrast detection, International Tissue Elasticity Conference
Gallina ME, Zhou Y, Johnson CJ, et al., 2013, Synthesis and Bioconjugation of Multifunctional Gold Nanorods for Specific Targeting and Photothermal Therapy of Cancer Cells, Bio-Nano-Photonics 2013
Harris-Birtill D, Gallina ME, Zhou Y, et al., 2013, Automatic image analysis of nanorod dimensions, Bio-Nano-Photonics 2013
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.