Imperial College London
Alternate

Professor Daniel Elson

Faculty of Medicine, Department of Surgery & Cancer

Professor of Surgical Imaging
 
 
 
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Contact

 

+44 (0)20 7594 1700daniel.elson Website CV

 
 
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Location

 

415 Bessemer BuildingBessemer BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Qi:2016:10.1038/srep25953,
author = {Qi, J and Elson, D},
doi = {10.1038/srep25953},
journal = {Scientific Reports},
title = {A high definition Mueller polarimetric endoscope for tissue characterisation},
url = {http://dx.doi.org/10.1038/srep25953},
volume = {6},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The contrast mechanism of medical endoscopy is mainly based on metrics of optical intensity and wavelength. As another fundamental property of light, polarization can not only reveal tissue scattering and absorption information from a different perspective, but can also provide insight into directional tissue birefringence properties to monitor pathological changes in collagen and elastin. Here we demonstrate a low cost wide field high definition Mueller polarimetric endoscope with minimal alterations to a rigid endoscope. We show that this novel endoscopic imaging modality is able to provide a number of image contrast mechanisms besides traditional unpolarized radiation intensity, including linear depolarization, circular depolarization, cross-polarization, directional birefringence and dichroism. This enhances tissue features of interest and additionally reveals tissue micro-structure and composition, which is of central importance for tissue diagnosis and image guidance for surgery. The potential applications of the Mueller polarimetric endoscope include wide field early epithelial cancer diagnosis, surgical margin detection and energy-based tissue fusion monitoring and could further benefit a wide range of endoscopic investigations through intra-operative guidance.
AU  - Qi,J
AU  - Elson,D
DO  - 10.1038/srep25953
PY  - 2016///
SN  - 2045-2322
TI  - A high definition Mueller polarimetric endoscope for tissue characterisation
T2  - Scientific Reports
UR  - http://dx.doi.org/10.1038/srep25953
UR  - https://www.nature.com/articles/srep25953
UR  - http://hdl.handle.net/10044/1/32754
VL  - 6
ER  -
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