Imperial College London

Professor Dan Elson

Faculty of MedicineDepartment of Surgery & Cancer

Professor of Surgical Imaging
 
 
 
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Contact

 

+44 (0)20 7594 1700daniel.elson Website

 
 
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Location

 

415 Bessemer BuildingBessemer BuildingSouth Kensington Campus

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Summary

 

Overview

Information on research areas and activities can be found on my research website:

Current research.

Research overview

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Ultrasound mediated tomography and elastography

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On this page: 
  • Viscosity measurement based on shear-wave laser speckle contrast analysis
  • Shear wave elasticity imaging based on acoustic radiation force and optical detection
  • Tracking shear waves in turbid medium by light: theory, simulation and experiment 

Tracking shear waves in turbid medium by light: theory, simulation and experiment
 
 
Experimental set-up showing (a) shear wave near surface, (b) shear wave at depth. 
 Simulated and experimental shear wave propagation results.

Shear wave elasticity imaging based on acoustic radiation force and optical detection
  Experiment set-up. DAO: the distance between optical and acoustic axis, which can be adjusted by using the translation  stage (not shown in the figure), AMP: power amplifier, WG:  waveform generator and DG: delay generator. The ultrasound  absorbing material minimises the ultrasound reflection. The  size of the tank is 30 3 20 3 7.8 cm.
 Scanning scheme for the heterogeneous phantom. Position  O indicates the starting position for optical axis in two scanning  runs. A and B are two different acoustic axis positions.
 Optical contrast difference (DC) as a function of time and DAO in three homogenous phantoms of different stiffness. It  can be seen that for a given DAO, the optical signal always peaks earlier and is better defined for a stiffer phantom.

Viscosity measurement based on shear-wave laser speckle contrast analysis
 
Shear-wave laser speckle contrast analysis (SW-LASCA) experimental setup
 Schematic for detecting continuous shear waves with SWLASCA  method.
 Speckle contrast difference due to continuous shear wave generated  by an ultrasound mechanical index (MI) of 1.28. Standard  deviation is produced with three repeated measurements.

Collaborators

Dr Lei Su, Queen Mary University of London, Single fibre endoscopy, 2016

Professor Hui MA, Tsinghua University, China, Polarization-resolved imaging, 2016

Lipei Song, Institute of Modern Optics, Nankai University, Tianjin, 300071, China, Laser Speckle Contrast Imaging, 2013

Danail Stoyanov, University College London, 2008

Lena Maier-Hein, German Cancer Research Centre (DKFZ), 2011

Professor Laura Marcu, University of California, Davis, Time-resolved fluorescence spectroscopy, 2006

Research Staff

Nabavi,E

Tziraki,M

Singh,M

Harris-Birtill,D

Gallina,ME

Clancy,N

Research Student Supervision

Avila,F, Concurrent Robotic Red-Flagging Framework for GI endoscopy

Lin,J, A self-calibrated endoscopic structured light system using multispectral detection

Zhou,Y, The Applications of Gold Nanoparticles in Photothermal Therapy for Cancer Treatment

Li,R, Ultrasound modulated optical tomography in optical diffuse medium using acoustic radiation force

Tatla,T

Li,S

CHENG,Y, Detecting tissue optical and mechanical properties with an ultrasound - modulated optical imaging system

Qi,J, Development of Optical Polarisation Resolved Endoscopy

Song,L, Endoscopic Laser Speckle Contrast Analysis for Tissue Perfusion

Sauvage,V, Fluorescence and Diffuse Reflectance Spectroscopy and Endoscopy for Tissue Analysis

WOOD,TOBIAS, Dynamic Hyperspectral and Polarized Endoscopic Imaging

KOH,KEVIN, Multimodal Multispectral Optical Endoscopic Imaging with Endomicroscopy for Biomedical Applications