ProfessorDavidBrooks

Binda KH, Lillethorup TP, Real CC, Baerentzen SL, Nielsen MN, Orlowski D, Brooks DJ, Chacur M, Landau AMet al., 2021, Exercise protects synaptic density in a rat model of Parkinson's disease, EXPERIMENTAL NEUROLOGY, Vol: 342, ISSN: 0014-4886

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• Citations: 13

Jeffrey N, Gatti M, Chang C, Whiteway L, Demirbozan U, Kovacs A, Pollina G, Bacon D, Hamaus N, Kacprzak T, Lahav O, Lanusse F, Mawdsley B, Nadathur S, Starck JL, Vielzeuf P, Zeurcher D, Alarcon A, Amon A, Bechtol K, Bernstein GM, Campos A, Rosell AC, Kind MC, Cawthon R, Chen R, Choi A, Cordero J, Davis C, DeRose J, Doux C, Drlica-Wagner A, Eckert K, Elsner F, Elvin-Poole J, Everett S, Ferte A, Giannini G, Gruen D, Gruendl RA, Harrison I, Hartley WG, Herner K, Huff EM, Huterer D, Kuropatkin N, Jarvis M, Leget PF, MacCrann N, McCullough J, Muir J, Myles J, Navarro-Alsina A, Pandey S, Prat J, Raveri M, Rollins RP, Ross AJ, Rykoff ES, Sanchez C, Secco LF, Sevilla-Noarbe I, Sheldon E, Shin T, Troxel MA, Tutusaus I, Varga TN, Yanny B, Yin B, Zhang Y, Zuntz J, Abbott TMC, Aguena M, Allam S, Andrade-Oliveira F, Becker MR, Bertin E, Bhargava S, Brooks D, Burke DL, Carretero J, Castander FJ, Conselice C, Costanzi M, Crocce M, da Costa LN, Pereira MES, De Vicente J, Desai S, Diehl HT, Dietrich JP, Doel P, Ferrero I, Flaugher B, Fosalba P, Garcia-Bellido J, Gaztanaga E, Gerdes DW, Giannantonio T, Gschwend J, Gutierrez G, Hinton SR, Hollowood DL, Hoyle B, Jain B, James DJ, Lima M, Maia MAG, March M, Marshall JL, Melchior P, Menanteau F, Miquel R, Mohr JJ, Morgan R, Ogando RLC, Palmese A, Paz-Chinchon F, Plazas AA, Rodriguez-Monroy M, Roodman A, Sanchez E, Scarpine V, Serrano S, Smith M, Soares-Santos M, Suchyta E, Tarle G, Thomas D, To C, Weller Jet al., 2021, Dark Energy Survey Year 3 results: Curved-sky weak lensing mass map reconstruction, MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Vol: 505, Pages: 4626-4645, ISSN: 0035-8711

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• Citations: 4

Jost ST, Visser-Vandewalle V, Rizos A, Loehrer PA, Silverdale M, Evans J, Samuel M, Petry-Schmelzer JN, Sauerbier A, Gronostay A, Barbe MT, Fink GR, Ashkan K, Antonini A, Martinez-Martin P, Chaudhuri KR, Timmermann L, Dafsari HSet al., 2021, Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease, NPJ PARKINSONS DISEASE, Vol: 7

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• Citations: 14

Sevilla-Noarbe I, Bechtol K, Kind MC, Rosell AC, Becker MR, Drlica-Wagner A, Gruendl RA, Rykoff ES, Sheldon E, Yanny B, Alarcon A, Allam S, Amon A, Benoit-Levy A, Bernstein GM, Bertin E, Burke DL, Carretero J, Choi A, Diehl HT, Everett S, Flaugher B, Gaztanaga E, Gschwend J, Harrison I, Hartley WG, Hoyle B, Jarvis M, Johnson MD, Kessler R, Kron R, Kuropatkin N, Leistedt B, Li TS, Menanteau F, Morganson E, Ogando RLC, Palmese A, Paz-Chinchon F, Pieres A, Pond C, Rodriguez-Monroy M, Smith JA, Stringer KM, Troxel MA, Tucker DL, de Vicente J, Wester W, Zhang Y, Abbott TMC, Aguena M, Annis J, Avila S, Bhargava S, Bridle SL, Brooks D, Brout D, Castander FJ, Cawthon R, Chang C, Conselice C, Costanzi M, Crocce M, da Costa LN, Pereira MES, Davis TM, Desai S, Dietrich JP, Doel P, Eckert K, Evrard AE, Ferrero I, Fosalba P, Garcia-Bellido J, Gerdes DW, Giannantonio T, Gruen D, Gutierrez G, Hinton SR, Hollowood DL, Honscheid K, Huff EM, Huterer D, James DJ, Jeltema T, Kuehn K, Lahav O, Lidman C, Lima M, Lin H, Maia MAG, Marshall JL, Martini P, Melchior P, Miquel R, Mohr JJ, Morgan R, Neilsen E, Plazas AA, Romer AK, Roodman A, Sanchez E, Scarpine V, Schubnell M, Serrano S, Smith M, Suchyta E, Tarle G, Thomas D, To C, Varga TN, Wechsler RH, Weller J, Wilkinson RDet al., 2021, Dark Energy Survey Year 3 Results: Photometric Data Set for Cosmology, ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, Vol: 254, ISSN: 0067-0049

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• Citations: 65

Vibholm AK, Landau AM, Moller A, Jacobsen J, Vang K, Munk OL, Orlowski D, Sorensen JCH, Brooks DJet al., 2021, NMDA receptor ion channel activation detected in vivo with [<SUP>18</SUP>F]GE-179 PET after electrical stimulation of rat hippocampus, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Vol: 41, Pages: 1301-1312, ISSN: 0271-678X

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• Citations: 12

Gatti M, Sheldon E, Amon A, Becker M, Troxel M, Choi A, Doux C, MacCrann N, Navarro-Alsina A, Harrison I, Gruen D, Bernstein G, Jarvis M, Secco LF, Ferte A, Shin T, McCullough J, Rollins RP, Chen R, Chang C, Pandey S, Tutusaus I, Prat J, Elvin-Poole J, Sanchez C, Plazas AA, Roodman A, Zuntz J, Abbott TMC, Aguena M, Allam S, Annis J, Avila S, Bacon D, Bertin E, Bhargava S, Brooks D, Burke DL, Carnero Rosell A, Carrasco Kind M, Carretero J, Castander FJ, Conselice C, Costanzi M, Crocce M, da Costa LN, Davis TM, De Vicente J, Desai S, Diehl HT, Dietrich JP, Doel P, Drlica-Wagner A, Eckert K, Everett S, Ferrero I, Frieman J, Garcia-Bellido J, Gerdes DW, Giannantonio T, Gruendl RA, Gschwend J, Gutierrez G, Hartley WG, Hinton SR, Hollowood DL, Honscheid K, Hoyle B, Huff EM, Huterer D, Jain B, James DJ, Jeltema T, Krause E, Kron R, Kuropatkin N, Lima M, Maia MAG, Marshall JL, Miquel R, Morgan R, Myles J, Palmese A, Paz-Chinchon F, Rykoff ES, Samuroff S, Sanchez E, Scarpine V, Schubnell M, Serrano S, Sevilla-Noarbe I, Smith M, Soares-Santos M, Suchyta E, Swanson MEC, Tarle G, Thomas D, To C, Tucker DL, Varga TN, Wechsler RH, Weller J, Wester W, Wilkinson RDet al., 2021, Dark energy survey year 3 results: weak lensing shape catalogue, MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Vol: 504, Pages: 4312-4336, ISSN: 0035-8711

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• Citations: 1

Eskildsen SF, Iranzo A, Stokholm MG, Staer K, Ostergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Borghammer P, Santamaria J, Moller A, Gaig C, Brooks DJ, Tolosa E, Ostergaard L, Pavese Net al., 2021, Impaired cerebral microcirculation in isolated REM sleep behaviour disorder, BRAIN, Vol: 144, Pages: 1498-1508, ISSN: 0006-8950

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• Citations: 4

Kinnerup MB, Sommerauer M, Damholdt MF, Schaldemose JL, Ismail R, Terkelsen AJ, Staer K, Hansen A, Fedorova TD, Knudsen K, Skjaerbaek C, Borghammer P, Pavese N, Brooks DJ, Nahimi Aet al., 2021, Preserved noradrenergic function in Parkinson's disease patients with rest tremor, NEUROBIOLOGY OF DISEASE, Vol: 152, ISSN: 0969-9961

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• Citations: 9

Brooks DJ, 2021, Future Imaging in Dementia, SEMINARS IN NUCLEAR MEDICINE, Vol: 51, Pages: 303-308, ISSN: 0001-2998

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• Citations: 3

Napier KJ, Gerdes DW, Lin HW, Hamilton SJ, Bernstein GM, Bernardinelli PH, Abbott TMC, Aguena M, Annis J, Avila S, Bacon D, Bertin E, Brooks D, Burke DL, Rosell AC, Kind MC, Carretero J, Costanzi M, Da Costa LN, De Vicente J, Diehl HT, Doel P, Everett S, Ferrero I, Fosalba P, García-Bellido J, Gruen D, Gruendl RA, Gutierrez G, Hollowood DL, Honscheid K, Hoyle B, James DJ, Kent S, Kuehn K, Kuropatkin N, Maia MAG, Menanteau F, Miquel R, Morgan R, Palmese A, Paz-Chinchón F, Plazas AA, Sanchez E, Scarpine V, Serrano S, Sevilla-Noarbe I, Smith M, Suchyta E, Swanson MEC, To C, Walker AR, Wilkinson RDet al., 2021, No evidence for orbital clustering in the extreme trans-Neptunian objects, Planetary Science Journal, Vol: 2

The apparent clustering in longitude of perihelion ϖ and ascending node Ω of extreme trans-Neptunian objects (ETNOs) has been attributed to the gravitational effects of an unseen 5–10 Earth-mass planet in the outer solar system. To investigate how selection bias may contribute to this clustering, we consider 14 ETNOs discovered by the Dark Energy Survey, the Outer Solar System Origins Survey, and the survey of Sheppard and Trujillo. Using each survey's published pointing history, depth, and TNO tracking selections, we calculate the joint probability that these objects are consistent with an underlying parent population with uniform distributions in ϖ and Ω. We find that the mean scaled longitude of perihelion and orbital poles of the detected ETNOs are consistent with a uniform population at a level between 17% and 94% and thus conclude that this sample provides no evidence for angular clustering.

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• Citations: 31

Thomsen MB, Jacobsen J, Lillethorup TP, Schacht AC, Simonsen M, Romero-Ramos M, Brooks DJ, Landau AMet al., 2021, In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Vol: 41, Pages: 819-830, ISSN: 0271-678X

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• Citations: 20

Brooks DJ, 2021, Imaging Familial and Sporadic Neurodegenerative Disorders Associated with Parkinsonism, NEUROTHERAPEUTICS, Vol: 18, Pages: 753-771, ISSN: 1933-7213

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• Citations: 3

Farmen K, Nissen SK, Stokholm MG, Iranzo A, Ostergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Borghammer P, Santamaria J, Moller A, Gaig C, Brooks DJ, Tolosa E, Pavese N, Romero-Ramos Met al., 2021, Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 118, ISSN: 0027-8424

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• Citations: 27

Hilton M, Sifón C, Naess S, Madhavacheril M, Oguri M, Rozo E, Rykoff E, Adhikari S, Aguena M, Aiola S, Allam S, Amodeo S, Amon A, Annis J, Ansarinejad B, Abbott TMC, Aros-Bunster C, Austermann JE, Avila S, Bacon D, Battaglia N, Beall JA, Becker DT, Bernstein GM, Bertin E, Bhandarkar T, Bhargava S, Bond JR, Brooks D, Burke DL, Calabrese E, Carrasco Kind M, Carretero J, Choi SK, Choi A, Conselice C, Da Costa LN, Costanzi M, Crichton D, Crowley KT, Dünner R, Denison EV, Devlin MJ, Dicker SR, Diehl HT, Dietrich JP, Doel P, Duff SM, Duivenvoorden AJ, Dunkley J, Everett S, Ferraro S, Ferté A, Flaugher B, Frieman J, Ferrero I, Gallardo PA, García-Bellido J, Gaztanaga E, Giles P, Golec JE, Gralla MB, Grandis S, Gruen D, Gerdes DW, Gruendl RA, Gschwend J, Gutierrez G, Han D, Hartley WG, Hasselfield M, Hill JC, Hilton GC, Hincks AD, Hinton SR, Ho SPP, Honscheid K, Hoyle B, Hubmayr J, Huffenberger KM, Hughes JP, Jaelani AT, Jain B, James DJ, Jeltema T, Kent S, Knowles K, Koopman BJ, Kuehn K, Lahav O, Lima M, Lin YT, Lokken M, Loubser SI, MacCrann N, Maia MAG, Marriage TA, Martin J, McMahon J, Melchior Pet al., 2021, The atacama cosmology telescope: A catalog of &gt;4000 Sunyaev–Zel’dovich galaxy clusters, Astrophysical Journal, Supplement Series, Vol: 253, ISSN: 0067-0049

We present a catalog of 4195 optically confirmed Sunyaev–Zel’dovich (SZ) selected galaxy clusters detected with signal-to-noise ratio >4 in 13,211 deg2 of sky surveyed by the Atacama Cosmology Telescope (ACT). Cluster candidates were selected by applying a multifrequency matched filter to 98 and 150 GHz maps constructed from ACT observations obtained from 2008 to 2018 and confirmed using deep, wide-area optical surveys. The clusters span the redshift range 0.04 < z < 1.91 (median z = 0.52). The catalog contains 222 z > 1 clusters, and a total of 868 systems are new discoveries. Assuming an SZ signal versus mass-scaling relation calibrated from X-ray observations, the sample has a 90% completeness mass limit of M500c > 3.8 × 1014 Me, evaluated at z = 0.5, for clusters detected at signal-to-noise ratio >5 in maps filtered at an angular scale of 2 4. The survey has a large overlap with deep optical weak-lensing surveys that are being used to calibrate the SZ signal mass-scaling relation, such as the Dark Energy Survey (4566 deg2), the Hyper Suprime-Cam Subaru Strategic Program (469 deg2), and the Kilo Degree Survey (825 deg2). We highlight some noteworthy objects in the sample, including potentially projected systems, clusters with strong lensing features, clusters with active central galaxies or star formation, and systems of multiple clusters that may be physically associated. The cluster catalog will be a useful resource for future cosmological analyses and studying the evolution of the intracluster medium and galaxies in massive clusters over the past 10 Gyr.

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• Citations: 47

Mullin S, Stokholm MG, Hughes D, Mehta A, Parbo P, Hinz R, Pavese N, Brooks DJ, Schapira AHet al., 2021, Brain Microglial Activation Increased in Glucocerebrosidase (<i>GBA</i>) Mutation Carriers without Parkinson's disease, MOVEMENT DISORDERS, Vol: 36, Pages: 774-779, ISSN: 0885-3185

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• Citations: 36

Femminella GD, Livingston NR, Raza S, van der Doef T, Frangou E, Love S, Busza G, Calsolaro V, Carver S, Holmes C, Ritchie CW, Lawrence RM, McFarlane B, Tadros G, Ridha BH, Bannister C, Walker Z, Archer H, Coulthard E, Underwood B, Prasanna A, Koranteng P, Karim S, Junaid K, McGuinness B, Passmore AP, Nilforooshan R, Macharouthu A, Donaldson A, Thacker S, Russell G, Malik N, Mate V, Knight L, Kshemendran S, Tan T, Holscher C, Harrison J, Brooks DJ, Ballard C, Edison Pet al., 2021, Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer's subjects?, Alzheimers Research & Therapy, Vol: 13, Pages: 1-11, ISSN: 1758-9193

BackgroundType 2 diabetes is a risk factor for Alzheimer’s disease (AD), and AD brain shows impaired insulin signalling. The role of peripheral insulin resistance on AD aetiopathogenesis in non-diabetic patients is still debated. Here we evaluated the influence of insulin resistance on brain glucose metabolism, grey matter volume and white matter lesions (WMLs) in non-diabetic AD subjects.MethodsIn total, 130 non-diabetic AD subjects underwent MRI and [18F]FDG PET scans with arterial cannula insertion for radioactivity measurement. T1 Volumetric and FLAIR sequences were acquired on a 3-T MRI scanner. These subjects also had measurement of glucose and insulin levels after a 4-h fast on the same day of the scan. Insulin resistance was calculated by the updated homeostatic model assessment (HOMA2). For [18F]FDG analysis, cerebral glucose metabolic rate (rCMRGlc) parametric images were generated using spectral analysis with arterial plasma input function.ResultsIn this non-diabetic AD population, HOMA2 was negatively associated with hippocampal rCMRGlc, along with total grey matter volumes. No significant correlation was observed between HOMA2, hippocampal volume and WMLs.ConclusionsIn non-diabetic AD, peripheral insulin resistance is independently associated with reduced hippocampal glucose metabolism and with lower grey matter volume, suggesting that peripheral insulin resistance might influence AD pathology by its action on cerebral glucose metabolism and on neurodegeneration.

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Tanoglidis D, Drlica-Wagner A, Wei K, Li TS, Sánchez J, Zhang Y, Peter AHG, Feldmeier-Krause A, Prat J, Casey K, Palmese A, Sánchez C, DeRose J, Conselice C, Gagnon L, Abbott TMC, Aguena M, Allam S, Avila S, Bechtol K, Bertin E, Bhargava S, Brooks D, Burke DL, Carnero Rosell A, Carrasco Kind M, Carretero J, Chang C, Costanzi M, Da Costa LN, De Vicente J, Desai S, Diehl HT, Doel P, Eifler TF, Everett S, Evrard AE, Flaugher B, Frieman J, García-Bellido J, Gerdes DW, Gruendl RA, Gschwend J, Gutierrez G, Hartley WG, Hollowood DL, Huterer D, James DJ, Krause E, Kuehn K, Kuropatkin N, Maia MAG, March M, Marshall JL, Menanteau F, Miquel R, Ogando RLC, Paz-Chinchón F, Romer AK, Roodman A, Sanchez E, Scarpine V, Serrano S, Sevilla-Noarbe I, Smith M, Suchyta E, Tarle G, Thomas D, Tucker DL, Walker ARet al., 2021, Shadows in the dark: Low-surface-brightness galaxies discovered in the dark energy survey, Astrophysical Journal, Supplement Series, Vol: 252, ISSN: 0067-0049

We present a catalog of 23,790 extended low-surface-brightness galaxies (LSBGs) identified in ~5000 deg2 from the first three years of imaging data from the Dark Energy Survey (DES). Based on a single-component Sérsic model fit, we define extended LSBGs as galaxies with g-band effective radii Reff (g) > 2."5 and mean surface brightness μmeff (g )> 24.2 mag arcsec-2. We find that the distribution of LSBGs is strongly bimodal in (g-r) versus (g-i) color space. We divide our sample into red (g-i≥0.60) and blue (g-i<0.60) galaxies and study the properties of the two populations. Redder LSBGs are more clustered than their blue counterparts and are correlated with the distribution of nearby (z<0.10) bright galaxies. Red LSBGs constitute ~33% of our LSBG sample, and ~30% of these are located within 1° of low-redshift galaxy groups and clusters (compared to ~8% of the blue LSBGs). For nine of the most prominent galaxy groups and clusters, we calculate the physical properties of associated LSBGs assuming a redshift derived from the host system. In these systems, we identify 41 objects that can be classified as ultradiffuse galaxies, defined as LSBGs with projected physical effective radii Reff > 1.5 kpc and central surface brightness μ0 (g )> 24.0 mag arcsec-2. The wide-area sample of LSBGs in DES can be used to test the role of environment on models of LSBG formation and evolution.

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• Citations: 25

Jarvis M, Bernstein GM, Amon A, Davis C, Leget PF, Bechtol K, Harrison I, Gatti M, Roodman A, Chang C, Chen R, Choi A, Desai S, Drlica-Wagner A, Gruen D, Gruendl RA, Hernandez A, MacCrann N, Meyers J, Navarro-Alsina A, Pandey S, Plazas AA, Secco LF, Sheldon E, Troxel MA, Vorperian S, Wei K, Zuntz J, Abbott TMC, Aguena M, Allam S, Avila S, Bhargava S, Bridle SL, Brooks D, Carnero Rosell A, Kind MC, Carretero J, Costanzi M, da Costa LN, De Vicente J, Diehl HT, Doel P, Everett S, Flaugher B, Fosalba P, Frieman J, Garcia-Bellido J, Gaztanaga E, Gerdes DW, Gutierrez G, Hinton SR, Hollowood DL, Honscheid K, James DJ, Kent S, Kuehn K, Kuropatkin N, Lahav O, Maia MAG, March M, Marshall JL, Melchior P, Menanteau F, Miquel R, Ogando RLC, Paz-Chinchon F, Rykoff ES, Sanchez E, Scarpine V, Schubnell M, Serrano S, Sevilla-Noarbe I, Smith M, Suchyta E, Swanson MEC, Tarle G, Varga TN, Walker AR, Wester W, Wilkinson RDet al., 2021, Dark Energy Survey year 3 results: point spread function modelling, MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Vol: 501, Pages: 1282-1299, ISSN: 0035-8711

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• Citations: 24

Thomsen MB, Ferreira SA, Schacht AC, Jacobsen J, Simonsen M, Betzer C, Jensen PH, Brooks DJ, Landau AM, Romero-Ramos Met al., 2021, PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats, NEUROBIOLOGY OF DISEASE, Vol: 149, ISSN: 0969-9961

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• Citations: 27

Xu Z, Anderson KN, Saffari SE, Lawson RA, Chaudhuri KR, Brooks D, Pavese Net al., 2021, Progression of sleep disturbances in Parkinson's disease: a 5-year longitudinal study, JOURNAL OF NEUROLOGY, Vol: 268, Pages: 312-320, ISSN: 0340-5354

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• Citations: 25

Knudsen K, Fedorova TD, Horsager J, Andersen KB, Skjaerbaek C, Berg D, Schaeffer E, Brooks DJ, Pavese N, Van den Berge N, Borghammer Pet al., 2021, Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson's Disease Subtypes, JOURNAL OF PARKINSONS DISEASE, Vol: 11, Pages: 1677-1687, ISSN: 1877-7171

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• Citations: 22

Edison P, Calsolaro V, Hinz R, Femminella GD, Pasqualetti G, Buckley CJ, Gentleman S, Brooks DJet al., 2020, Microglial activation evaluated using flutriciclamide (11F-GE180) in subjects with cognitive impairment: Neuroimaging /Optimal neuroimaging measures for ..., Alzheimer's and Dementia, ISSN: 1552-5260

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Leng F, Hinz R, Dani M, Hampshire A, Gentleman S, Brooks D, Edison Pet al., 2020, Tau formation is associated with microglial activation in more widespread cortical areas than amyloid deposition: Multimodal neuroimaging comparison, Alzheimer's and Dementia, ISSN: 1552-5260

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Edison P, Femminella GD, van der Doef T, Carver S, Holmes C, Ritchie CW, Lawrence RM, McFarlane B, Tadros G, Ridha BH, Bannister C, Walker Z, Archer H, Coulthard E, Underwood B, Prasanna A, Koranteng P, Karim S, Junaid K, McGuinness B, Passmore AP, Nilforooshan R, Macharouthu A, Donaldson A, Thacker S, Russell G, Malik N, Mate V, Knight L, Kshemendran S, Harrison JE, Ballard C, Brooks DJet al., 2020, Behavioural symptoms in Alzheimer's disease are associated with white matter lesions (WML) volume and are independent of atrophy and hypometabolism: Neuroimaging /Optimal..., Alzheimer's and Dementia, ISSN: 1552-5260

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Edison P, Leng F, Hinz R, Dani M, Hampshire A, Gentleman S, Brooks DJet al., 2020, Influence of microglial activation on structural and functional connectivity in mild cognitive impairment subjects: Development of new models and analysis methods/neuroinflammation, Alzheimer's and Dementia, ISSN: 1552-5260

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Smith M, D'Andrea CB, Sullivan M, Möller A, Nichol RC, Thomas RC, Kim AG, Sako M, Castander FJ, Filippenko AV, Foley RJ, Galbany L, González-Gaitán S, Kasai E, Kirshner RP, Lidman C, Scolnic D, Brout D, Davis TM, Gupta RR, Hinton SR, Kessler R, Lasker J, Macaulay E, Wolf RC, Zhang B, Asorey J, Avelino A, Bassett BA, Calcino J, Carollo D, Casas R, Challis P, Childress M, Clocchiatti A, Crawford S, Frohmaier C, Glazebrook K, Goldstein DA, Graham ML, Hoormann JK, Kuehn K, Lewis GF, Mandel KS, Morganson E, Muthukrishna D, Nugent P, Pan YC, Pursiainen M, Sharp R, Sommer NE, Swann E, Thomas BP, Tucker BE, Uddin SA, Wiseman P, Zheng W, Abbott TMC, Annis J, Avila S, Bechtol K, Bernstein GM, Bertin E, Brooks D, Burke DL, Carnero Rosell A, Carrasco Kind M, Carretero J, Cunha CE, da Costa LN, Davis C, De Vicente J, Diehl HT, Eifler TF, Estrada J, Frieman J, García-Bellido J, Gaztanaga E, Gerdes DW, Gruen D, Gruendl RA, Gschwend J, Gutierrez G, Hartley WG, Hollowood DL, Honscheid K, Hoyle B, James DJ, Johnson MWG, Johnson MD, Kuropatkin N, Li TS, Lima M, Maia MAG, March M, Marshall JL, Martini P, Menanteau F, Miller CJ, Miquel Ret al., 2020, First cosmology results using supernovae ia from the dark energy survey: Survey overview, performance, and supernova spectroscopy, Astronomical Journal, Vol: 160, ISSN: 0004-6256

We present details on the observing strategy, data-processing techniques, and spectroscopic targeting algorithms for the first three years of operation for the Dark Energy Survey Supernova Program (DES-SN). This five-year program using the Dark Energy Camera mounted on the 4 m Blanco telescope in Chile was designed to discover and follow supernovae (SNe) Ia over a wide redshift range (0.05 < z < 1.2) to measure the equation-of-state parameter of dark energy. We describe the SN program in full: Strategy, observations, data reduction, spectroscopic follow-up observations, and classification. From three seasons of data, we have discovered 12,015 likely SNe, 308 of which have been spectroscopically confirmed, including 251 SNe Ia over a redshift range of 0.017 < z < 0.85. We determine the effective spectroscopic selection function for our sample and use it to investigate the redshiftdependent bias on the distance moduli of SNe Ia we have classified. The data presented here are used for the first cosmology analysis by DES-SN ("DES-SN3YR"), the results of which are given in Dark Energy Survey Collaboration et al. The 489 spectra that are used to define the DES-SN3YR sample are publicly available at https://des.ncsa.illinois.edu/releases/sn.

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Edison P, Raza S, Femminella GD, Blunt EG, Carver S, Livingston NR, Nowell J, Holmes C, Ritchie CW, Lawrence RM, McFarlane B, Tadros G, Ridha BH, Bannister C, Walker Z, Archer H, Coulthard E, Underwood B, Prasanna A, Koranteng P, Karim S, Junaid K, McGuinness B, Nilforooshan R, Macharouthu A, Donaldson A, Thacker S, Russell G, Malik N, Mate V, Knight L, Kshemendran S, Harrison JE, Brooks DJ, Passmore AP, Ballard Cet al., 2020, Relationship between spectral analysis, SUV and SUV Pons ratio as a measure of cerebral glucose metabolic rate in Alzheimer's Disease: Neuroimaging/multi-modal comparisons., Alzheimer's and Dementia, ISSN: 1552-5260

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Staer K, Iranzo A, Stokholm MG, Ostergaard K, Serradell M, Otto M, Svendsen KB, Garrido A, Vilas D, Santamaria J, Moller A, Gaig C, Brooks DJ, Borghammer P, Tolosa E, Pavese Net al., 2020, Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder, PARKINSONISM & RELATED DISORDERS, Vol: 81, Pages: 89-93, ISSN: 1353-8020

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• Citations: 10

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Thomsen MB, Schacht AC, Alstrup AKO, Jacobsen J, Lillethorup TP, Baerentzen SL, Noer O, Orlowski D, Elfving B, Muller HK, Brooks DJ, Landau AMet al., 2020, Preclinical PET Studies of [<SUP>11</SUP>C]UCB-J Binding in Minipig Brain, MOLECULAR IMAGING AND BIOLOGY, Vol: 22, Pages: 1290-1300, ISSN: 1536-1632

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