Imperial College London

ProfessorDavidBrooks

Faculty of MedicineDepartment of Brain Sciences

Visiting Professor
 
 
 
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Contact

 

david.brooks

 
 
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Assistant

 

Ms Hyacinth Henry +44 (0)20 3313 3172

 
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Location

 

U106Block B Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Edison:2018:10.3233/JAD-179929,
author = {Edison, P and Brooks, D},
doi = {10.3233/JAD-179929},
journal = {Journal of Alzheimers Disease},
pages = {S339--S351},
title = {Role of neuroinflammation in Alzheimer’s trajectory and in vivo quantification using PET},
url = {http://dx.doi.org/10.3233/JAD-179929},
volume = {64},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Recent evidence suggests that neuroinflammation and immunity play a significant role in Alzheimer’s disease and other neurodegenerative diseases. It has also been observed that, independent of the presence of aggregated proteins, neuroinflammation could be present in different neurodegenerative diseases. It has also been suggested that neuroinflammation could occur well ahead of amyloid deposition in AD. Recent genetic studies and other preclinical studies specifically point to a role of neuroinflammation and, in this review, we evaluate the evidence of neuroinflammation in the Alzheimer’s disease trajectory and the different imaging modalities by which we could monitor neuroinflammation in vivo in humans.
AU - Edison,P
AU - Brooks,D
DO - 10.3233/JAD-179929
EP - 351
PY - 2018///
SN - 1387-2877
SP - 339
TI - Role of neuroinflammation in Alzheimer’s trajectory and in vivo quantification using PET
T2 - Journal of Alzheimers Disease
UR - http://dx.doi.org/10.3233/JAD-179929
UR - http://hdl.handle.net/10044/1/60954
VL - 64
ER -