Dr Duncan Casey is Industrial Liaison Fellow at the Bristol Centre for Functional Nanomaterials, where he leads interactions between the Centre for Doctoral Training and companies in the area, alongside his own portfolio of research in sensor instrumentation and soft-matter nanomaterials. He also has specific remit to develop BCFN research towards commercial implementation, and runs a number of spin-off and entrepreneurship courses for staff and students. At Imperial College, he is a visiting lecturer collaborating with Prof David Klug, Prof Oscar Ces and Dr Nick Brooks on a range of biophotonics, instrumentation and soft matter projects.
Duncan was formerly a post-doctoral researcher in the Proxomics group of the Institute of Chemical Biology, based in the Department of Chemistry. His research both then and now centres upon the development of instrumentation and chemical tools for the manipulation and analysis of single cells, with a wider focus on the processes involved in cancer and aging. The Proxomics project is a collaboration between Imperial College, Aston University and the University of Glasgow, funded by the EPSRC.
He was also a member of the Membrane Biophysics group, where he completed his Ph.D. in 2012 after investigating the interactions between drug molecules and cell membranes in the movement of such molecules through the body. His lipid and surface chemistry experience have led to involvement in projects ranging in scope from medical imaging to diet and nutrition.
Outside his academic interests, Duncan is a founder member of anywhereHPLC, an Imperial Innovations-backed spin-out venture developing hand-held analytical tools for industrial, environmental and medical applications. The technology features a number of unique, proprietary features that allow the power and flexibility of traditional lab-based tools to be compressed into a pocket-sized platform, allowing reliable, rapid and affordable analysis at the point of sampling.
Villangca M, Casey DR, Glückstad J, Optically-controlled platforms for transfection and single- and sub-cellular surgery, Biophysical Reviews, ISSN:1867-2469
et al., 2014, Amphiphilic drug interactions with model cellular membranes are influenced by lipid chain-melting temperature, Journal of the Royal Society Interface, Vol:11, ISSN:1742-5689
et al., 2014, The grab-and-drop protocol: a novel strategy for membrane protein isolation and reconstitution from single cells, Analyst, Vol:139, ISSN:0003-2654, Pages:3296-3304
et al., 2015, A Novel, all-optical tool for controllable and non-destructive poration of cells with single-micron resolution