Imperial College London

ProfessorEricAlton

Faculty of MedicineNational Heart & Lung Institute

Chair in Gene Therapy
 
 
 
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Contact

 

+44 (0)20 7594 7937e.alton

 
 
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Location

 

Emmanuel Kaye BuildingRoyal Brompton Campus

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Summary

 

Summary

Eric Alton is Professor of Gene Therapy and Respiratory Medicine, National Heart & Lung Institute, Imperial College London and Honorary Consultant Physician, Royal Brompton Hospital

Professor Alton was educated at Jesus College, Cambridge and Westminster Medical School and subsequently undertook six years of general medical training.  Over the last fifteen years, he has been involved in developing gene therapy for cystic fibrosis and angiogenesis, including three clinical trials.

Professor Alton coordinates the UK CF Gene Therapy Consortium which brings together the three centres in the UK (Edinburgh and Oxford Universities and Imperial College), including approximately 80 clinicians and scientists focused on this problem.

 

Publications

Journals

Pabary R, Singh C, Morales S, et al., 2016, Antipseudomonal Bacteriophage Reduces Infective Burden and Inflammatory Response in Murine Lung, Antimicrobial Agents and Chemotherapy, Vol:60, ISSN:0066-4804, Pages:744-751

Ahmad F, Irving S, Alton E, et al., 2015, Multiple breath washouts in children can be shortened without compromising quality, European Respiratory Journal, Vol:46, ISSN:0903-1936, Pages:1814-1816

Alton E, Armstrong D, Bayfield K, et al., 2015, A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF REPEATED NEBULISATION OF NON-VIRAL CFTR GENE THERAPY IN PATIENTS WITH CYSTIC FIBROSIS, Pediatric Pulmonology, Vol:50, ISSN:8755-6863, Pages:262-262

Alton EWFW, Armstrong DK, Ashby D, et al., 2015, Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial, Lancet Respiratory Medicine, Vol:3, ISSN:2213-2600, Pages:684-691

Alton EWFW, Boyd AC, Porteous DJ, et al., 2015, A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trail, American Journal of Respiratory and Critical Care Medicine, Vol:192, ISSN:1073-449X, Pages:1389-1392

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