Imperial College London


Faculty of MedicineDepartment of Medicine

Non-Clinical Lecturer







Commonwealth BuildingHammersmith Campus





Dr Edward Chambers is a Non-Clinical Lecturer in the Nutrition and Dietetics Research Group. His applied in vivo human research aims to advance understanding of nutritional intervention in health and disease.

His main area of interest is investigating the interplay between dietary fibre and the composition and functional activities of the gut microbiome in the regulation of metabolic homeostasis in humans. At Imperial College London, his principal responsibility has been the conduct and management of BBSRC and NIHR BRC funded projects which have investigated the beneficial role of the gut-derived short chain fatty acid (SCFA) propionate to metabolic health. Published studies have developed in vivo proof-of-concept for propionate as a novel therapeutic to improve body weight management and reduce hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD).



Chambers ES, Byrne CS, Rugyendo A, et al., 2018, The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease., Diabetes Obes Metab

Chambers ES, Byrne CS, Aspey K, et al., 2018, Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans, Diabetes Obesity & Metabolism, Vol:20, ISSN:1462-8902, Pages:1034-1039

Garcia-Perez I, Posma JM, Gibson R, et al., 2017, Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial, Lancet Diabetes & Endocrinology, Vol:5, ISSN:2213-8587, Pages:184-195

Pingitore A, Chambers ES, Hill T, et al., 2017, The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro, Diabetes Obesity & Metabolism, Vol:19, ISSN:1462-8902, Pages:257-265


Garcia Perez I, Posma JM, Gibson R, et al., 2017, MODERNIZING DIETARY ASSESSMENT, KARGER, Pages:286-287, ISSN:0250-6807

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