Imperial College London

Academic Research Pharmacist

Faculty of MedicineDepartment of Medicine

Senior Lead Pharmacist







7N12Commonwealth BuildingHammersmith Campus





Esmita is the academic research pharmacist at the National Institute of Health Research Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance. The HPRU is a partnership between Imperial College London, Public Health England, Cambridge University Veterinary School, the Wellcome Trust Sanger Institute and Imperial College Health Partners North West London Academic Health Science Network. Esmita is currently undertaking her PhD at the centre. The title of her PhD is culture and team dynamics in the implementation of antimicrobial stewardship interventions. She is an investigator in a National Institute of Health Research Invention for Innovation award investigating the development and use of a point of care personalized clinical decision support tool for antimicrobial prescribing. In addition, Esmita is a visiting researcher at Haukeland University in Norway where she has been involved in the implementation of the national Norwegian antimicrobial stewardship programme.  

Throughout her time at Imperial the focus of Esmita's research has been behaviour change interventions in the field of antimicrobial stewardship and the role of mobile health technologies to influence decision making.


Esmita has a degree in Pharmacy from the University of London (MPharm). Following several years of clinical posts at Addenbrooke's Hospital in Cambridge Esmita obtained a MSc in Infectious Diseases from the London School of Hygiene and Tropical Medicine. Previous to joining Imperial as a researcher Esmita held several Clinical posts at the Royal Free Hospital, the North Middlesex Hospital and was the Scientific Secretariat to a Department of Health Scientific Expert Advisory Group.


  • Charani E, Gharbi M, Othman S, Hickson M, Al-fituri A, Frost G, Holmes A. Lack of weight recording in patients being administered narrow therapeutic index antibiotics – a prospective cross-sectional study. BMJ Open 2014. In press.
  • King D, Jabbar A, Charani E, et al. Redesigning the ‘choice architecture’ of hospital prescription charts: a mixed methods study incorporating in-situ simulation. BMJ Open 2014. In press. 
  • Cooke J, Stephens P, Ashiru-Oredope D, Charani E, Dryden M, Fry C, Hand K, Holmes A, Howard P, Johnson AP, Livermore DM, Mansell P, McNulty CA, Wellsteed S, Hopkins S, Sharland M. Longitudinal trends and cross-sectional analysis of English national hospital antibacterial use over 5 years (2008-13): working towards hospital prescribing quality measures.  J Antimicrob Chemother. 2014 Oct 10.
  • Charani E, Castro-Sanchez E, Moore LS, Holmes A. Do smartphone applications in healthcare require a governance and legal framework? It depends on the application! BMC Med 2014; 12:29. Doi: 10.1186/1741-7015-12-29.
  • Charani E, Holmes AH. Antimicrobial stewardship programmes: the need for wider engagement. BMJ Qual Saf 2013; 22(11): 885-7.
  • Castro-Sanchez E, Charani E, Drumright LN, Sevdalis N, Shah N, Holmes AH. Fragmentation of care threatens patient safety in peripheral vascular catheter management in acute care- a qualitative study. PLos One 2014; 9(1): e86167. doi: 10.1371/journal.pone.0086167. eCollection 2014.
  • Charani E, Castro-Sanchez E, Sevdalis N, Kyratsis Y, et al. Understanding the determinants of antimicrobial prescribing within acute care: the role of ‘prescribing etiquette’. Clin Infect Dis 2013;57(2):188-96.
  • Charani E, Castro-Sanchez E, Sevdalis N, Kyratsis Y, et al. Understanding the determinants of antimicrobial prescribing within acute care: the role of ‘prescribing etiquette’. In press at Clin Infect Dis.
  • Charani E, Kyratsis Y, Lawson W, Wickens H, Brannigan E, Moore L and Holmes A. An analysis of the development and implementation of a smartphone application for the delivery of antimicrobial prescribing policy: lessons learnt. J Antimicrob Chemother 2012 Dec 19 [epub ahead of print].
  • Davey P, Brown E, Charani E, Fenelon L, Gould I, Holmes A, Ramsay C et al. Interventions to improve antibiotic practices for hospital inpatients. Cochrane Review. Cochrane Database of Syst Rev 2012, in press.
  • Oshiru-Oredope D, Sharland M, Charani E, McNulty C, Cooke J. ARHAI: Improving the quality of antibiotic prescribing in the NHS by developing a new Antimicrobial Stewardship Programme  - Start Smart  - Then Focus. J Antimicrob Chemother 2012 Jul;67 Suppl 1:i51-63.
  • Edwards E, Charani E, Sevdalis E et al. Optimising infection prevention and control practice using behaviour change: a systematic review. Lancet Infect Dis 2012 Apr;12(4):318-29.
  • Charani E, Edwards E, Sevdalis N, Sibley E et al. Behaviour change strategies to influence antimicrobial prescribing: a systematic review. Clin Infect Dis 2011 53: 651-662.
  • Charani E, Cooke J, Holmes, A. Antibiotic stewardship programmes – what’s missing? J Antimicrob Chemother. 2010 Nov;65(11):2275-7.
  • Cooke J, Alexander K, Charani E, Hand K, Hills T, et al. Antimicrobial stewardship: an evidence-based, antimicrobial self-assessment toolkit (ASAT) for acute hospitals. J Antimicrob Chemother. 2010 Dec;65(12):2669-73.
  • Charani E, Cooke J. Promoting prudent use of antibiotics. The Pharmaceutical Journal. 2008; 281:564.




Birgand GJC, Troughton R, Moore L, et al., Blogging in infectious diseases and clinical microbiology: Assessment of the 'blogosphere' content, Infection Control and Hospital Epidemiology, ISSN:1559-6834


Charani E, Castro Sanchez E, Nathwany D, et al., What are the key elements of an antimicrobial stewardship programme on a global scale – results of a global survey, European Congress of Clinical Microbiology and Infectious Diseases

Charani E, De Barra E, Gharbi M, et al., Antibiotic prescribing in acute medical and surgical ward rounds – A prospective cohort study, European Congress of Clinical Microbiology and Infectious Diseases

Charani E, Tarrant C, Moorthy K, et al., Who is responsible for antimicrobial management of the post-operative surgical patient? – An ethnographic study, European Congress of Clinical Microbiology and Infectious Diseases

Charani E, Tarrant C, Sevdalis N, et al., Contrasts and contradictions in antibiotic decision making on medical and surgical ward rounds – A qualitative study, European Congress of Clinical Microbiology and Infectious Diseases

More Publications