Publications
62 results found
Salek-Ardakani S, Cota E, Bignell E, 2012, Host-fungal interactions: key players of antifungal immunity., Expert Rev Anti Infect Ther, Vol: 10(2), Pages: 149-151
Bolanos-Garcia VM, Lischetti T, Matak-Vinkovic D, et al., 2011, Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site (vol 19, pg 1691, 2011), Structure, Vol: 19, Pages: 1895-1895, ISSN: 1878-4186
Bolanos-Garcia VM, Lischetti T, Matak-Vinkovic D, et al., 2011, Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site, STRUCTURE, Vol: 19, Pages: 1691-1700, ISSN: 0969-2126
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- Citations: 59
Sheppard C, Camara B, Shadrin A, et al., 2011, Reprint of: Inhibition of Escherichia coli RNAp by T7 Gp2 protein: Role of Negatively Charged Strip of Amino Acid Residues in Gp2, JOURNAL OF MOLECULAR BIOLOGY, Vol: 412, Pages: 832-841, ISSN: 0022-2836
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- Citations: 3
Salgado PS, Yan R, Taylor JD, et al., 2011, Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus <i>Candida albicans</i>, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 108, Pages: 15775-15779, ISSN: 0027-8424
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- Citations: 59
Taylor JD, Zhou Y, Salgado PS, et al., 2011, Atomic Resolution Insights into Curli Fiber Biogenesis, STRUCTURE, Vol: 19, Pages: 1307-1316, ISSN: 0969-2126
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- Citations: 68
Sheppard C, Camara B, Shadrin A, et al., 2011, Inhibition of <i>Escherichia coli</i> RNAp by T7 Gp2 Protein: Role of Negatively Charged Strip of Amino Acid Residues in Gp2, JOURNAL OF MOLECULAR BIOLOGY, Vol: 407, Pages: 623-632, ISSN: 0022-2836
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- Citations: 9
Salgado PS, Yan R, Rowan F, et al., 2011, Expression, crystallization and preliminary X-ray data analysis of NT-Als9-2, a fungal adhesin from <i>Candida albicans</i>, ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, Vol: 67, Pages: 467-470
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- Citations: 3
Cota E, 2011, Als adhesins - Structural basis for the broad specificity to host-cell ligands by Candida albicans, Host-fungal interactions: pathogenicity versus immunity, Pages: 149-151
Als (agglutinin-like sequence) glycoproteins have been associated with binding of host-cell surface proteins and small peptides of random sequence, the formation of biofilms and amyloid fibers. High-resolution structures of N-terminal Als domains show that ligand recognition relies on a motif capable of binding flexible C termini of peptides in extended conformation. These data establish NT-Als adhesins as a separate family of peptide-binding proteins and an unexpected adhesion system for primary, widespread protein–protein interactions at the Candida/host-cell interface. The new structural information also provides potential templates for the design of novel antifungals.
Salgado PS, Taylor JD, Cota E, et al., 2011, Extending the usability of the phasing power of diselenide bonds: SeCys SAD phasing of CsgC using a non-auxotrophic strain, ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, Vol: 67, Pages: 8-13, ISSN: 2059-7983
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- Citations: 15
Ramboarina S, Garnett JA, Zhou M, et al., 2010, Structural Insights into Serine-rich Fimbriae from Gram-positive Bacteria, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 285, Pages: 32446-32457, ISSN: 0021-9258
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- Citations: 42
Yan R, Simpson PJ, Matthews SJ, et al., 2010, Backbone <SUP>1</SUP>H, <SUP>15</SUP>N, <SUP>13</SUP>C and Ile, Leu, Val methyl chemical shift assignments for the 33.5 kDa N-terminal domain of Candida albicans ALS1, BIOMOLECULAR NMR ASSIGNMENTS, Vol: 4, Pages: 187-190, ISSN: 1874-2718
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- Citations: 8
Camara B, Liu M, Reynolds J, et al., 2010, T7 phage protein Gp2 inhibits the <i>Escherichia coli</i> RNA polymerase by antagonizing stable DNA strand separation near the transcription start site, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 107, Pages: 2247-2252, ISSN: 0027-8424
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- Citations: 53
Thomas JC, Green JL, Howson RI, et al., 2010, Interaction and dynamics of the <i>Plasmodium</i> <i>falciparum</i> MTIP-MyoA complex, a key component of the invasion motor in the malaria parasite, MOLECULAR BIOSYSTEMS, Vol: 6, Pages: 494-498, ISSN: 1742-206X
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- Citations: 25
Xu Y, Liu M, Simpson PJ, et al., 2009, Automated Assignment in Selectively Methyl-Labeled Proteins, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 131, Pages: 9480-+, ISSN: 0002-7863
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- Citations: 27
Salgado PS, Yan R, Hoyer L, et al., 2009, Structural Studies of Candida Albicans Pathogenicity Factors: ALS Adhesins Family, Publisher: INT UNION CRYSTALLOGRAPHY, Pages: S22-S23, ISSN: 2053-2733
Korotkova N, Yang Y, Le Trong I, et al., 2008, Binding of Dr adhesins of <i>Escherichia coli</i> to carcinoembryonic antigen triggers receptor dissociation, MOLECULAR MICROBIOLOGY, Vol: 67, Pages: 420-434, ISSN: 0950-382X
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- Citations: 53
Isaacson RL, Simpson PJ, Liu M, et al., 2007, A new labeling method for methyl transverse relaxation-optimized spectroscopy NMR spectra of alanine residues, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 129, Pages: 15428-+, ISSN: 0002-7863
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- Citations: 89
Cota E, Jones C, Simpson P, et al., 2006, The solution structure of the invasive tip complex from Afa/Dr fibrils, MOLECULAR MICROBIOLOGY, Vol: 62, Pages: 356-366, ISSN: 0950-382X
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- Citations: 40
Korotkova N, Cota E, Lebedin Y, et al., 2006, A subfamily of Dr adhesins of <i>Escherichia coli</i> bind independently to decay-accelerating factor and the N-domain of carcinoembryonic antigen, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 281, Pages: 29120-29130
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- Citations: 41
Saouros S, Edwards-Jones B, Reiss M, et al., 2005, A novel galectin-like domain from <i>Toxoplasma gondii</i> micronemal protein 1 assists the folding, assembly, and transport of a cell adhesion complex, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 280, Pages: 38583-38591
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- Citations: 59
Saouros S, Chen HA, Simpson P, et al., 2005, Letter to the Editor:: Complete resonance assignments of the C-terminal domain from MIC1:: A micronemal protein from <i>Toxoplasma gondii</i>, JOURNAL OF BIOMOLECULAR NMR, Vol: 31, Pages: 177-178, ISSN: 0925-2738
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- Citations: 7
Pettigrew D, Anderson KL, Billington J, et al., 2004, High resolution studies of the Afa/Dr adhesin DraE and its interaction with chloramphenicol, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 279, Pages: 46851-46857, ISSN: 0021-9258
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- Citations: 50
Anderson KL, Billington J, Pettigrew D, et al., 2004, An atomic resolution model for assembly, architecture, and function of the Dr adhesins, MOLECULAR CELL, Vol: 15, Pages: 647-657, ISSN: 1097-2765
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- Citations: 97
Cota E, Chen HA, Anderson KL, et al., 2004, Letter to the Editor:: Complete resonance assignments of the 'donor-strand complemented' AfaD:: The afimbrial invasin from Diffusely Adherent <i>E-coli</i>, JOURNAL OF BIOMOLECULAR NMR, Vol: 29, Pages: 411-412, ISSN: 0925-2738
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- Citations: 9
Anderson KL, Cota E, Simpson P, et al., 2004, Letter to the Editor:: Complete resonance assignments of a 'donor-strand complemented' AfaE:: The afimbrial adhesin from Diffusely Adherent <i>E-coli</i>, JOURNAL OF BIOMOLECULAR NMR, Vol: 29, Pages: 409-410, ISSN: 0925-2738
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- Citations: 10
Pettigrew D, Roversi P, Bhella D, et al., 2004, Structural studies of CD55 interactions with pathogen-derived ligands, MOLECULAR IMMUNOLOGY, Vol: 41, Pages: 293-293, ISSN: 0161-5890
Cota E, Steward A, Fowler SB, et al., 2001, The folding nucleus of a fibronectin type III domain is composed of core residues of the immunoglobulin-like fold, JOURNAL OF MOLECULAR BIOLOGY, Vol: 305, Pages: 1185-1194, ISSN: 0022-2836
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- Citations: 91
Cota E, Hamill SJ, Fowler SB, et al., 2000, Two proteins with the same structure respond very differently to mutation: The role of plasticity in protein stability, JOURNAL OF MOLECULAR BIOLOGY, Vol: 302, Pages: 713-725, ISSN: 0022-2836
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- Citations: 66
Hamill SJ, Cota E, Chothia C, et al., 2000, Conservation of folding and stability within a protein family: The tyrosine corner as an evolutionary cul-de-sac, JOURNAL OF MOLECULAR BIOLOGY, Vol: 295, Pages: 641-649, ISSN: 0022-2836
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- Citations: 92
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