Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Imperial College Junior Research Fellow



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Emmanuel Kaye BuildingRoyal Brompton Campus






BibTex format

author = {Roda, C and Mahmoud, O and Peralta, GP and Fuertes, E and Granell, R and Serra, I and Henderson, J and Jarvis, D and Garcia-Aymerich, J},
doi = {ije/dyz128},
journal = {International Journal of Epidemiology},
pages = {131--141},
title = {Physical-activity trajectories during childhood and lung function at 15 years: findings from the ALSPAC cohort},
url = {},
volume = {49},
year = {2020}

RIS format (EndNote, RefMan)

AB - BACKGROUND: Although physical activity has many known health benefits, its association with lung function in childhood/adolescence remains unclear. We examined the association of physical-activity trajectories between 11 and 15 years with lung function at 15 years in 2266 adolescents. METHODS: A population-based cohort of 14 305 singleton births alive at 1 year was recruited in the UK population-based Avon Longitudinal Study of Parents and Children cohort. Physical activity (counts/minute and moderate-to-vigorous physical activity) was assessed for 7 days using an accelerometer at 11, 13 and 15 years. We identified sex-specific physical-activity trajectories applying K-means for longitudinal data in children with at least two accelerometer measurements (n = 3584). We then estimated the sex-specific associations of these trajectories with post-bronchodilation lung-function parameters using multivariable linear-regression models (n = 2266, 45% boys). RESULTS: Fewer than 7% of participants met the WHO physical-activity recommendations (i.e. daily average of at least 60 minutes of moderate-to-vigorous physical activity). Boys were substantially more active than girls. In both sexes, we identified three distinct physical-activity trajectories ('low': 39.8% boys, 45.8% girls; 'moderate': 42.9% boys, 41.4% girls; and 'high' physical activity: 17.3% boys, 12.8% girls). Girls in the moderate and high physical-activity trajectories had 0.11 L [95% confidence interval (CI): 0.04-0.19] and 0.15 L (95% CI: 0.03-0.26) higher forced vital capacity than their less-active peers. No association was observed in boys. CONCLUSIONS: Higher childhood physical activity relates to higher lung-function levels in adolescent girls. A better understanding of the mechanisms underlying this association should be pursued.
AU - Roda,C
AU - Mahmoud,O
AU - Peralta,GP
AU - Fuertes,E
AU - Granell,R
AU - Serra,I
AU - Henderson,J
AU - Jarvis,D
AU - Garcia-Aymerich,J
DO - ije/dyz128
EP - 141
PY - 2020///
SN - 1464-3685
SP - 131
TI - Physical-activity trajectories during childhood and lung function at 15 years: findings from the ALSPAC cohort
T2 - International Journal of Epidemiology
UR -
UR -
UR -
UR -
VL - 49
ER -