Imperial College London


Faculty of Natural SciencesDepartment of Life Sciences

Professor of Structural Matrix Biology



+44 (0)20 7594 7701e.hohenester




406Sir Ernst Chain BuildingSouth Kensington Campus





Erhard Hohenester is an X-ray crystallographer and biochemist investigating the molecular mechanisms of extracellular matrix biosynthesis, assembly and signalling. He trained as a chemist in his native Austria and received his PhD in Biophysics from the University of Basel (Switzerland) in 1995. He joined Imperial College London in 1998 with a Wellcome Trust Senior Research Fellowship, which he held for 15 years. In 2009 he was promoted to Professor of Structural Matrix Biology. His current research is funded by a Wellcome Trust Senior Investigator Award.

Group members

If you want to join the lab, please search NAT00096

Dr Patricia Paracuellos (Postdoc)

Ms Sadaf-Ahmahni Hussain (Technician)

Mr Doug Sammon (PhD Student)

Selected Publications

Journal Articles

Pulido D, Hussain S-A, Hohenester E, 2017, Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111, Structure, Vol:25, ISSN:0969-2126, Pages:530-535

Briggs DC, Yoshida-Moriguchi T, Zheng T, et al., 2016, Structural basis of laminin binding to the LARGE glycans on dystroglycan, Nature Chemical Biology, Vol:12, ISSN:1552-4450, Pages:810-+

Paracuellos P, Briggs DC, Carafoli F, et al., 2015, Insights into Collagen Uptake by C-type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4, Structure, Vol:23, ISSN:0969-2126, Pages:2133-2142

More Publications